REBOOT trial (@RebootTrial) header
REBOOT trial (@RebootTrial) profile picture

REBOOT is a pragmatic trial testing the efficacy of chronic betablockers after MI & LVEF above 40%. Sponsor: CNIC. 8500 Pts to be recruited in Spain & Italy.

España
Joined November 2017
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⁉️Do b-blockers benefit post-MI patients in 2025?Saturday 11am, Hotline session 3. We close the loop of @RebootTrial Started in 2018, with an amazing team in 109 hospitals working without any compensation. This is breathtaking. THANK YOU! youtu.be/2nwQ44AN1dM?si=4uvr… @CNIC_CARDIO
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🎯 Do betablockers (BB) reduce MACE after MI with LVEF >40% and no heart failure?
20%Yes, BB improve outcome
51%NO, BB do not benefit
29%ONLY in mildly red LVEF
142 votes • Final results
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TEN HOT LINES ❤️‍🔥10 hot line sessions already released by @escardio #ESCcongress ❤️‍🔥They feature 42 major trials alongside 129 exciting additional studies ❤️‍🔥Spanish trials lead one of them, highlighitng ⬆️level of scientific research lnkd.in/d_mQCUJX @RosselloJavier #CardioX
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🏠 Home ❤️
El @CNIC_CARDIO es un centro de investigación de excelencia reconocida internacionalmente, dedicado a comprender las bases fundamentales de la salud y la enfermedad #cardiovascular, con programas que abarcan desde la #investigación básica hasta ensayos clínicos avanzados. Está acreditado como Centro de Excelencia Severo Ochoa por la @AgEInves. +ℹ️ aei.gob.es/ayudas-concedidas…
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Absolutely! @RebootTrial 8500 patients, BETAMI and DANBLOCK trials together 6000 pt. All post-MI with EF>40%. This year at #ESCcongress2025 in our hometown MADRID this clinical dilemma will be solved once and forever
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REBOOT is closing out! We are ensuring that all events are documented, reported, and adequately adjudicated! A big thanks to all local investigators, who are doing their best to minimise losses to follow up. Shortly, we will lock and analyse the dataset!! @CNIC_CARDIO
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REBOOT trial retweeted
From @DapaTAVI, we wish you all the best in 2025. We hope to announce the results of @DapaTAVI soon, at the ACC congress. Vamosss @secardiologia @CNIC_CARDIO @shci_sec @SECgeriatrica @clinica_sec @JovenesSec @S_Raposeiras @Borjaibanez1 @RosselloXavier @ignamatsant @mvaduganathan
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Best wishes on behalf of the REBOOT community!
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💊🫀betablockers after ACS with LVEF>40%. controversy after REDUCE-MI and ABYSS trials. We are the largest trial on the topic (8500 pt enrolment completed‼️ ). Plans to present data in @escardio ESC congress 2025 in Madrid!! 📽️ here 👉 youtu.be/2nwQ44AN1dM?si=opmp…
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📊 have you voted❓ read the #OpenAccess 📚paper describing the design of REBOOT-CNIC trial 👉 academic.oup.com/ehjcvp/arti…
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what do you anticipate the results will be? POLL👉
81%neutral (no diff at all)
17%bblk reduce hard outcomes
3%bblks induce harm
0%i dont really care
36 votes • Final results
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what do you anticipate the results will be? POLL👉
81%neutral (no diff at all)
17%bblk reduce hard outcomes
3%bblks induce harm
0%i dont really care
36 votes • Final results
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📈 encuesta de uso de antiplaquetarios en SCA ‼️ oportunidad de mostrar si las guías de SCA han tenido impacto en vida real. cuantos más participemos, mejor veremos la tendencia de cambio (o no...) questionnaire.aplusaresearch…
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REBOOT trial retweeted
A punto de finalizar el reclutamiento del @RebootTrial !! 🚀🚀 Gracias a todos por vuestra implicación y compromiso !! 👏👏 @secardiologia @Borjaibanez1 @RosselloXavier @ResiSec @CNIC_CARDIO … 🔝
La noche del sábado 6 de abril se cerrará la plataforma de reclutamiento. Queda por tanto sólo esta semana para poder incluir los últimos pacientes y cruzar la meta! Muchas gracias a tod@s por vuestro grandísimo esfuerzo. @Borjaibanez1 @CNIC_CARDIO @JovenesSec @RosselloXavier
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ÚLTIMA SEMANA activa para reclutamiento!! vamos!! último esfuerzo!!
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La noche del sábado 6 de abril se cerrará la plataforma de reclutamiento. Queda por tanto sólo esta semana para poder incluir los últimos pacientes y cruzar la meta! Muchas gracias a tod@s por vuestro grandísimo esfuerzo. @Borjaibanez1 @CNIC_CARDIO @JovenesSec @RosselloXavier
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8️⃣,4️⃣2️⃣3️⃣ participants have already been recruited in the REBOOT (tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion) trial! 📆 7️⃣7️⃣ patients to go! 🚀 🎯 Target = 8️⃣,5️⃣0️⃣0️⃣
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8️⃣,3️⃣9️⃣9️⃣ participants have already been recruited in the REBOOT (tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion) trial! 📆 1️⃣0️⃣1️⃣ patients to go! 🚀 🎯 Target = 8️⃣,5️⃣0️⃣0️⃣
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8️⃣,3️⃣8️⃣1️⃣ participants have already been recruited in the REBOOT (tREatment with Beta-blockers after myOcardial infarction withOut reduced ejection fracTion) trial! 📆 Less than 2️⃣% of the estimated sample size to be recruited 🚀 🎯 Target = 8️⃣,5️⃣0️⃣0️⃣
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