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Reda

@RedaKeddar

Senior Scientist @AstraZeneca interested in understanding mechanisms of resistance to cancer immunotherapy.

 Cambridge, England
Joined October 2015
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Thrilled to share our work characterising acquired resistance to immune checkpoint blockade (ICB) in the post-progression setting, now published in @jitcancer @sitcancer ! jitc.bmj.com/content/14/5/e0…
Pan-cancer analysis in the real-world setting uncovers immunogenomic drivers of acquired resistance...

Pan-cancer analysis in the real-world setting uncovers immunogenomic drivers of acquired resistance...

Background Immune checkpoint blockade (ICB) has revolutionized cancer therapy, yet resistance—both primary and acquired—remains a significant obstacle, affecting the majority of patients.Methods...

jitc.bmj.com
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New #JITC article: "Pan-cancer analysis in the real-world setting uncovers immunogenomic drivers of acquired resistance post-immunotherapy" jitc.bmj.com/content/14/5/e0… @kalender_atak @imartincorena @AdamJSchoenfeld @AstraZeneca
Image from Journal for ImmunoTherapy of Cancer (@jitcancer)
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This work is an exemplar of a cross-functional and cross-institutional team effort, gathering diverse backgrounds and expertise to tackle a very important translational question. Huge thanks to all co-authors for all their contributions in shaping this work.
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#Immunotherapy #ComputationalBiology #DataScience #AcquiredResistance #NSCLC #HNSCC #TNBC
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Join us for a great scientific get-together in our brand new DISCovery centre. Looking forward!
Cambridge Computational Oncology (@CamCompOnco) profile pictureCambridge Computational Oncology@CamCompOnco1 Mar 2024
Only few places left! 🧐 Next Cam Comp Onco meeting ⏲️ March 15th, 3-6 pm 🛖 hosted by AZ at the DISC 📢 @OMRueda @AppleTreeWoman @RedaKeddar ❗️❗️Register by march 10th❗️❗️ forms.office.com/e/iRW1Eak3t…
Image from Cambridge Computational Oncology (@CamCompOnco)
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Only few places left! 🧐 Next Cam Comp Onco meeting ⏲️ March 15th, 3-6 pm 🛖 hosted by AZ at the DISC 📢 @OMRueda @AppleTreeWoman @RedaKeddar ❗️❗️Register by march 10th❗️❗️ forms.office.com/e/iRW1Eak3t…
Image from Cambridge Computational Oncology (@CamCompOnco)
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Miriam Merad, MD, PhD, Elected to the National Academy of Medicine for Seminal Work in Immunology and Cell Biology | Mount Sinai - New York shar.es/agmF0C @IcahnMountSinai @SinaiImmunol @theNAMedicine
Image from Mount Sinai Tisch Cancer Center (@TischCancer)
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Amazing and dogma-challenging work showing how primed CD8+ T cells can eliminate MHCI-null tumour cells via an innate-like mechanism. Congratulations!
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Nature research paper: Y chromosome loss in cancer drives growth by evasion of adaptive immunity go.nature.com/46iUGhu
Y chromosome loss in cancer drives growth by evasion of adaptive immunity

Y chromosome loss in cancer drives growth by evasion of adaptive immunity

Nature - Loss of the Y chromosome in tumour cells is associated with a poor prognosis for patients with bladder cancer by causing local T cell exhaustion, which also increases the response to...

nature.com
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Thrilled to begin my tenure as the new president of @iuis_online! We are working toward demystifying immunology research, fostering global collaborations & bringing new immunotherapies to patients everywhere 🤝 Read more here: iuis.org/about/who-we-are/ed…
White background featuring the logo of the International Union of Immunological Societies (IUIS) and their slogan, “Immunology without Borders”

ALT White background featuring the logo of the International Union of Immunological Societies (IUIS) and their slogan, “Immunology without Borders”

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