Obesity & Inflammation nitter.cf/i/broadcasts/1mGPaZPyk…

Discussing Weight Loss: 3 Minute Script Dr. Jack Cush's 3 Minute Script as discussed in his Introducing Weight Loss video. buff.ly/dSSvddI

Chinese 52 wk study of XKH004, a novel, SC, humanized anti-17A/F in 323 active AS pts Rx q4 wks vs PBO. @ Wk 16, XKH004 was superior for ASAS40 (45.4% vs 19.4%; P<0.001), improved to 66% by wk 52. buff.ly/6ZIzPu2

Obesity and Rheumatic Disease Presented as part of RheumNow's "The Obesity Imperative" campaign. buff.ly/uKTEYyR

Join us for Tuesday Nite Rheumatology on September 22 for: Obesity Treatment & Safety Experts will tackle: • GLP-1/GIP therapies • Lifestyle & bariatric interventions • Treatment selection & safety • Cost & compounding concerns • Sarcopenia & bone health • The future of precision obesity care Featuring Dr. Juliana Simonetti and Dr. Grace Wright, moderated by Dr. Jack Cush. 📅 Sept. 22 ⏰ 7 PM ET | 6 PM CT | 4 PM PT buff.ly/znEw37u

🚨NEW FROM EULAR: In biologic-naive PsA, how do IL-23i, TNFi, and IL-17i compare on joint outcomes? 🦴Real-world data on TJC/SJC now available. Sponsored by AbbVie Medical Affairs + Health Impact. buff.ly/TNRmi3V

Review of HLA-B27 What’s New? HLA-B27 remains the dominant genetic link to spondyloarthritis (SpA) across the age spectrum, but B27 related clinical expression diverges between children and adults. New mechanistic data on autoreactive T cells, HLA-B27 misfolding, and gut-joint trafficking point to new plausible, targetable pathways. buff.ly/MAIQw7Q

Added IVIG is Effective in Myositis A small randomized controlled trial demonstrates that intravenous immunoglobulin (IVIG) added to cortocosteroids lead to greater and faster improvements in patients with newly diagnosed idiopathic inflammatory myopathies (IIMs). buff.ly/lO2TUmm

Bariatric Surgery in the Era of GLP-1RA Overweight/obesity is a chronic multi-system disease that can impair physical and mental health. It now affects almost 1 in 3 Canadians. Multiple recent guidelines have therefore suggested using waist measurements, in addition to BMI, to diagnose obesity. One such measure is the waist-to-height ratio, with a value above 0.5 indicating increased adiposity. buff.ly/DkrkSGE

4,197 pts from the UK Biobank met fibromyalgia criteria, yet 72.6% had NOT received a diagnosis. Non-Dx assoc w/ male, older age, milder sxs or other pain Dx (OA, CRPS, CFS), lower polysymptomatic distress scores, and less frequent fatigue. buff.ly/pAVWEtQ

Research at Cedars-Sinai used synthetic noncoding RNA TY1 in a bleomycin mouse model of scleroderma, noting improved exercise tolerance, CV function, lung hydroxyproline, skin thickness, less fibrosis. TY1 attenuates the cGAS/STING pathway buff.ly/DW56x3o

OL study of tofacitinib in 20 juvenile DM pts w/ calcinosis cutis (11 boys; age 10.4 yrs; CC x 31 mos). Calcinosis assessed by CT scan showed decr Agatston score from 6,349 to 4,007. No SAE. buff.ly/GSEhoJQ

Join us for Tuesday Nite Rheumatology on September 22 for: 🔴 Obesity Treatment & Safety Experts will tackle: • GLP-1/GIP therapies • Lifestyle & bariatric interventions • Treatment selection & safety • Cost & compounding concerns • Sarcopenia & bone health • The future of precision obesity care Featuring Dr. Juliana Simonetti and Dr. Grace Wright, moderated by Dr. Jack Cush. 📅 Sept. 22 ⏰ 7 PM ET | 6 PM CT | 4 PM PT buff.ly/znEw37u

Metanalysis of 87 studies shows predictors of #MTX response: early Dz, low dz activity, early MTX initiation, and absence of erosive disease. Smoking and higher BMI were linked to reduced efficacy. buff.ly/8FevLWF

Obesity and Rheumatic Disease Presented as part of RheumNow's "The Obesity Imperative" campaign. buff.ly/uKTEYyR

QD Clinic: GLP-1s and History of Thyroid Cancer? Daric Mueller, PA-C, St. Clair Shores, MI, presents this case as part of RheumNow's "The Obesity Imperative" campaign, presented in September 2026. buff.ly/0ltVb1O

Early RA Referral Clinics Work! An outcomes study from the Leiden Early Arthritis Clinic (EAC) has shown substantially less diagnostic delay and better long-term outcomes when patients are referred to EAC compared to usual referrals. buff.ly/YqT9UwA

Obesity management goes far beyond the number on the scale. Watch our Four Pillars of Weight Loss video series, part of this month’s The Obesity Imperative campaign. What Are the Four Pillars of Obesity Management? Building a Multidisciplinary Program for Obesity & Arthritis Management Explore how a comprehensive, multidisciplinary approach can help reshape obesity care in rheumatology. buff.ly/LrWGynZ

QD Clinic: Bariatric Surgery "Curing" Arthritis? Dr. Richard Conway, Dublin, presents this QD Clinic as part of RheumNow's "The Obesity Imperative" campaign, presented in September 2026. buff.ly/GDZy8zy

Obesity Journal Club: Tuesday Nite Rheumatology The Obesity Journal Club explores the TOGETHER PsA and STEP 9 trials and what emerging evidence tells us about the relationship between obesity, weight loss, and rheumatic disease. Panelists discussed the results of these trials, how we consider obesity as both a comorbidity and part of the disease course, and shared practical strategies for addressing obesity in everyday rheumatology practice. buff.ly/WdZC9VN

Obesity and Rheumatic Disease Presented as part of RheumNow's "The Obesity Imperative" campaign. buff.ly/uKTEYyR