Rutter Lab@RutterLab
Jul 7United States
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We are excited to share a new preprint from our amazing postdoc @alexjbott ! Alex designed a new CRISPR screening platform called TRoUT-FISH to identify transcriptional activators and repressors of various genes of interest! Check out his tweetorial below!
Happy to share our new preprint from @RutterLab. To understand how genes are controlled, we developed a method we call TRoUT-FISH, using CRISPR + RNA-FISH. We found that glycolytic gene expression is fine-tuned by lineage specifying transcription factors.
biorxiv.org/content/10.64898…
Jul 7, 2026 · 4:58 PM UTC
Rutter Lab@RutterLab
Jul 7United States
United StatesConnected via United States App StoreAccount-level information, not a live location or per-post device.
This is a bit of a tale of two stories: we’re deeply intrigued by the biology and we think that this method is incredibly useful. It fills a gap in the field to ask gene-centric regulatory questions. We hope you enjoy the preprint, reach out with feedback!
