News and information about Spinocerebellar Ataxia research. Written by scientists in plain language that everyone can understand.
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LSVT stands for Lee Silverman Voice Therapy. It is a speech therapy program that is well researched and widely used in speech pathology for treating dysarthria (slurred or unclear speech) in Parkinson Disease. ataxia.org/scasourceposts/sn…
Could other brain cells besides neurons or nerve cells play an important role in spinocerebellar ataxia type 7 (SCA7)? A new study offers an important clue by looking beyond neurons and focusing on the brain's support cells called astrocytes. ataxia.org/scasourceposts/su…
Regular stationary bike training improves ataxia symptoms within months according to a clinical trial. ataxia.org/scasourceposts/pe…
Before a new drug or therapy can reach patients, researchers and regulatory agencies need evidence that it is safe and effective. One of the most reliable ways to gather this evidence is through a randomized controlled trial (RCT). ataxia.org/scasourceposts/wh…
A new matched stem cell model gives SCA1 researchers a clearer way to study disease mechanisms and test potential treatments. ataxia.org/scasourceposts/ne…
How the gut helps clean the brain: New evidence supports the importance of gut health and sleep management for people with neurodegenerative disorders. ataxia.org/scasourceposts/ho…
The functional Scale for the Assessment and Rating of Ataxia (f-SARA) is a streamlined clinical tool used to measure disease progression in ataxia. ataxia.org/scasourceposts/sn…
A new drug may help steady movement and improve daily life for people with ataxia-telangiectasia. ataxia.org/scasourceposts/le…
Tiny tags, big impact: new research reveals chemical tags on ataxin-3 protein influences its behavior and may contribute to brain cell death in SCA3. ataxia.org/scasourceposts/ho…
The Hauser Lab at the German Center for Neurodegenerative Diseases studies how genetic changes damage brain cells and lead to neurodegenerative diseases like Ataxia. ataxia.org/scasourceposts/sp…
Endpoints are clearly defined outcomes that are measured during a trial to help determine the effects of an intervention. Clinical trials usually include several types of endpoints, each serving a different purpose. ataxia.org/scasourceposts/sn…
Levacetylleucine, sold under the brand name Aqneursa, is an FDA-approved treatment for Niemann-Pick disease type C. Levacetylleucine is also in Phase III clinical trial for Ataxia-Telangiectasia and is being studied for the treatment of other diseases. ataxia.org/scasourceposts/sn…
Ever wonder if experiences early in life impact symptoms of a genetic disease? Researchers found that genetics isn’t the only thing to consider in SCA6. ataxia.org/scasourceposts/th…
Expanded access (sometimes called “compassionate use” or “pre-approval access”) is a way for patients to access medical products before they are approved for a particular condition. ataxia.org/scasourceposts/sn…
New mouse studies show that mutant ataxin-2 causes dramatically more damage in older animals, revealing aging as an independent driver of disease severity. ataxia.org/scasourceposts/th…
Walking tests in a hospital is not the same as walking at home. Wearable sensors show that real-world walking is more variable than in the hospital. ataxia.org/scasourceposts/we…
New research in SCA6 mouse models suggests boosting BDNF-TrkB signaling could change the game. ataxia.org/scasourceposts/mo…
New clues into SCA1: RNA gets trapped inside toxic ataxin-1 clumps in brain cells, disrupting the production of proteins and contributing to disease. ataxia.org/scasourceposts/an…
¿Te sientes cansado(a)? No estás solo(a). La fatiga es un síntoma común de las ataxias espinocerebelosas y afecta la calidad de vida. ataxia.org/scasourceposts/co…
A silent mutation occurs when a base in the DNA sequence is changed, but this change does not alter the resulting amino acid sequence. ataxia.org/scasourceposts/sn…
