Chandra Lab (@SChandraLab) header
Chandra Lab (@SChandraLab) profile picture

Chandra Lab

@SChandraLab

Dept. of Neurology & Neuroscience, Yale University School of Medicine, @YaleNeuro @NeurologyYale @Yale #Synaptic #Neurodegeneration

 New Haven, CT, United States
medicine.yale.edu/lab/chandra/
Joined November 2020
  • Tweets100
  • Following62
  • Followers348
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Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)Photo by Chandra Lab (@SChandraLab)
Chandra Lab retweeted
Yale Neuroscience (@YaleNeuro) profile picture
Yale Neuroscience@YaleNeuroJun 4
Lipofuscin accumulates in the brain with age and neurodegeneration. But what is it, where does it come from, and where does it go? The @SChandraLab built a lipofuscin brain atlas and shed light on its composition. medicine.yale.edu/news-artic…
Green fluorescing dots of lipofuscin in the brain of a mouse lacking PPT1. Image from the Chandra lab.

ALT Green fluorescing dots of lipofuscin in the brain of a mouse lacking PPT1. Image from the Chandra lab.

Chandra Lab (@SChandraLab) profile pictureChandra Lab@SChandraLabMay 26
Earlier this month, this exciting paper from previous PhD student in the lab, Sofia, came out! Take a look at her exciting work characterizing lipofuscin in aging and Neuronal Ceroid Lipofuscinosis! link.springer.com/article/10…
Lipofuscin accumulation in aging and CLN1 is associated with deficient de-S-acylation, lyso-mitoc...

Lipofuscin accumulation in aging and CLN1 is associated with deficient de-S-acylation, lyso-mitoc...

Acta Neuropathologica - Lipofuscin is an autofluorescent material that accrues in brain tissues with age and in Neuronal Ceroid Lipofuscinosis (NCL), a neurodegenerative disease with pediatric...

link.springer.com
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Chandra Lab retweeted
Yale Neuroscience (@YaleNeuro) profile picture
Yale Neuroscience@YaleNeuroMar 24
CONGRATS 🎉 to @YaleNeuro's Sreeganga Chandra (@SChandraLab), @Janghoolim, & Stephen Strittmatter, who recently received funding 💰 from the Blavatnik Family Foundation for their innovative research in the field of #neuroscience! 🧠 More 👇 ventures.yale.edu/news/blava…
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This #TraineeTuesday, meet @leah_harmon13, a @Yale_INP graduate student in the @SChandraLab! She was recently awarded the K. Patricia Cross Future Leaders Award at the 2024 annual meeting of the American Association of Colleges and Universities @aacu in Washington DC. 🥳 [1/5]
Headshot of Leah Harmon

ALT Headshot of Leah Harmon

Photo of Leah Harmon at the 2024 AACU conference

ALT Photo of Leah Harmon at the 2024 AACU conference

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Congratulations to Associate flash talk winners: @VidyadharDJ @KristaGFreeman @NeuroSwatiG @CoralZhou @jr2255 @lydiagrmai
Image from IntersectionsScienceFellows (@InterSciFellows)
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Thanks @InterSciFellows for highlighting and for this exciting opportunity! Looking forward to #ISFS2023! tinyurl.com/ISFS3 @SChandraLab @YaleNeuro @NeurologyYale
IntersectionsScienceFellows (@InterSciFellows) profile pictureIntersectionsScienceFellows@InterSciFellows17 Aug 2023
Dr. Vidyadhara Devarunda Jaganath is a postdoctoral associate in Dr. Chandra’s lab @Yale, where he investigates the genetics and cell biology of Parkinson’s disease, specifically studying endolysosomal dysfunctions. Welcome @VidyadharDJ to #ISFS2023! tinyurl.com/ISFS3
Image from IntersectionsScienceFellows (@InterSciFellows)
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Team Hafler having a great time at #CRNSanDiego2023 It’s been an amazing and inspiring conference! @ASAP_Research @SChandraLab!
Image from Varnica khetrapal, Ph.D (@VarnicaK)
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Today’s #TraineeTuesday star is @SChandraLab undergrad Risha Chakraborty, who won the Y-Work Award for Outstanding Student Employees 🥳 Postdoc @VidyadharDJ said she is “the best I have ever seen. She has done her work w/ utmost reliability and professionalism.” Read more ➡️[1/5]
Headshot of Risha Chakraborty in the lab.

ALT Headshot of Risha Chakraborty in the lab.

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Replying to @SChandraLab
@SChandraLab & the Greer Lab are diving into one of #ParkinsonsDisease's common, but less studied symptoms: loss of smell. Check out their study published in @SfNJournals to uncover the biological mechanisms behind this olfactory impairment👃 medicine.yale.edu/neuroscien…
Study Uncovers Biological Mechanism Behind Loss of Smell in Parkinson’s Patients

Study Uncovers Biological Mechanism Behind Loss of Smell in Parkinson’s Patients

In a new study published in Journal of Neuroscience, researchers uncover the biological mechanism behind loss of smell in Parkinson's patients.

medicine.yale.edu
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Postdoc @VidyadharDJ (@SChandraLab) is presenting [1:00 - 1:15] at #SfN22 on how auxilin mutations & clathrin-uncoating deficits lead to #Parkinson’s disease 🙌 Way to go @YaleNeuro researchers!! [4/4] abstractsonline.com/pp8/#!/1… -> nitter.cf/VidyadharDJ/status/159…
Vidyadhara D J (@VidyadharDJ) profile pictureVidyadhara D J@VidyadharDJ12 Nov 2022
Started off #SfN2022 on a high note with the @movedisorder-PAS satellite event! If you are around, come meet me to talk about auxilin-linked #Parkinson's biorxiv.org/content/10.1101/… Poster: Trainee Prof. Dev. Awards on 12th evening Talk: Nanosymposium on 15th afternoon
Image from Vidyadhara D J (@VidyadharDJ)
Image from Vidyadhara D J (@VidyadharDJ)
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🚨🧠Interested in applying to the Yale Interdepartmental Neuroscience graduate program? Sign up for our zoom open house on 11/28/22, 6-8 PM EST. Come meet our students and faculty and hear all about our incredible program. 🧠🚨@Yale_INP Register here docs.google.com/forms/d/e/1F…
Registration for Yale Neuroscience track open house November 28th, 2022

Registration for Yale Neuroscience track open house November 28th, 2022

Hello, we are excited to talk with you about our graduate program! We will have current students and faculty available to answer all your questions or simply tell you more about living in New Haven,...

docs.google.com
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#NationalPostdocAppreciationWeek 🥼🧪🫶 is underway! To find resources or community, check out the events organized by @YaleNeuro's postdoc committee. Please register using the link sent by email. Let’s see the spotlight 💡 shift to our valuable scientists!
Flyer of the National Postdoc Appreciation Week listing events organized by the Yale Neuroscience Postdoc Committee: a Postdoc Town Hall on Thursday, and Happy Hour on Friday.

ALT Flyer of the National Postdoc Appreciation Week listing events organized by the Yale Neuroscience Postdoc Committee: a Postdoc Town Hall on Thursday, and Happy Hour on Friday.

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One week left to apply to SYNAPSES! apply.interfolio.com/110988
Yale Neuroscience (@YaleNeuro) profile pictureYale Neuroscience@YaleNeuro8 Aug 2022
Calling all senior postdocs in #neuroscience! Applications are open for the 2022-2023 Yale SYNAPSES, our extramural postdoc seminar series. Apply to present your science at Yale! Deadline September 7th: apply.interfolio.com/110988 @KavliAtYale
Flyer for SYNAPSES "Seminars at Yale Neuroscience: Advanced PoStdoc Extramural Series" showing a call for application at this link: https://apply.interfolio.com/110988

ALT Flyer for SYNAPSES "Seminars at Yale Neuroscience: Advanced PoStdoc Extramural Series" showing a call for application at this link: https://apply.interfolio.com/110988

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📢Job alert!📢 We are hiring *multiple* tenure track faculty members at @YaleNeuro. Seeking candidates in neuroscience at large who will join a richly collaborative community that strives to foster an inclusive research environment. Please RT! apply.interfolio.com/110309
Full page describing that the Yale Department of Neuroscience is seeking to hire multiple tenure track faculty members. Deadline, October 15th, application at this link: https://apply.interfolio.com/110309

ALT Full page describing that the Yale Department of Neuroscience is seeking to hire multiple tenure track faculty members. Deadline, October 15th, application at this link: https://apply.interfolio.com/110309

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New @biorxivpreprint manuscript presents data indicating olfactory functional deficits observed in transgenic mice expressing the human A30P mutant alpha-synuclein recapitulate some of the features observed in #Parkinsons; From @SChandraLab & colleagues biorxiv.org/content/10.1101/…
Image from The Science of Parkinson's (@ScienceofPD)
Image from The Science of Parkinson's (@ScienceofPD)
Image from The Science of Parkinson's (@ScienceofPD)
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Chandra Lab retweeted
Lim Lab (@LimLabYale) profile picture
Lim Lab@LimLabYale18 Aug 2022
Another successful annual lab retreat with the @SChandraLab, @CaffertyLab, @guo_lab, and @BiedererLab. 🌴☀️🌳🏕 #SummerVibes
Image from Lim Lab (@LimLabYale)
Image from Lim Lab (@LimLabYale)
Image from Lim Lab (@LimLabYale)
Image from Lim Lab (@LimLabYale)
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New @Yale research suggests that several neurodegenerative disorders associated with aging may originate not in the nervous system, but in the gut. medicine.yale.edu/news-artic…
Does Parkinson’s Disease Begin in the Gut?

Does Parkinson’s Disease Begin in the Gut?

Yale research suggests that several neurodegerative diseases may originate not in the nervous system, but in the gut microbiome.

medicine.yale.edu
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Calling all senior postdocs in #neuroscience! Applications are open for the 2022-2023 Yale SYNAPSES, our extramural postdoc seminar series. Apply to present your science at Yale! Deadline September 7th: apply.interfolio.com/110988 @KavliAtYale
Flyer for SYNAPSES "Seminars at Yale Neuroscience: Advanced PoStdoc Extramural Series" showing a call for application at this link: https://apply.interfolio.com/110988

ALT Flyer for SYNAPSES "Seminars at Yale Neuroscience: Advanced PoStdoc Extramural Series" showing a call for application at this link: https://apply.interfolio.com/110988

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Of course, the best part of the @YaleMed #Diversity Supplement Workshop was hearing from a Post-Bacc funded applicant about their experience and thoughts - thank you hanks you Nigel Wade and mentor Dr. Chandra! #YaleDiversityPanel #DEIInAction
Naftali Kaminski (@KaminskiMed) profile pictureNaftali Kaminski@KaminskiMed2 Aug 2022
Dr. Holmes from @NIDAnews provides additional information and mentions the Diversity Supplement Professional Development and Networking Workshop held by @NIH at the end of August - check it out if you are eligible! #YaleDiversityPanel #DEIInAction event.roseliassociates.com/n…
Image from Naftali Kaminski (@KaminskiMed)
Image from Naftali Kaminski (@KaminskiMed)
Image from Naftali Kaminski (@KaminskiMed)
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Special shout-out to the post-baccs for their Rockettes performance during the group photo! 👯🎵🧠
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Join us on Tuesday, 05/17 at 6 PM EST for our BBS e-Lecture Series talk featuring Dr. Sreeganga Chandra (@SChandraLab)! Learn about #SynapticProteins involved in #SynapticMaintenance, #Neurodegeneration and #Parkinsons! Register: bit.ly/3rBmYAh
Dr. Chandra received her undergraduate and master’s degrees from India. She earned a Ph.D. in Chemistry with a specialization in Biochemistry from Purdue University, USA. Dr. Chandra did her postdoctoral training with Dr. Thomas Südhof at the University of Texas Southwestern Medical Center. A member of the faculty of Yale School of Medicine since 2007, Dr. Chandra is an Associate Professor in the Departments of Neurology and Neuroscience. Dr. Chandra’s laboratory explores two inter-related themes –synapse maintenance and neurodegeneration. In particular, the lab investigates Parkinson’s disease genes and risk alleles that encode synaptic proteins and how they impact synaptic structure, function, and neuronal health. The long-term goal of the research in the Chandra lab is to parlay a basic understanding of Parkinson’s disease genes for the development of early disease-modifying therapies. Tuesday, April 17th at 06:00 PM Eastern Standard Time (EST):

ALT Dr. Chandra received her undergraduate and master’s degrees from India. She earned a Ph.D. in Chemistry with a specialization in Biochemistry from Purdue University, USA. Dr. Chandra did her postdoctoral training with Dr. Thomas Südhof at the University of Texas Southwestern Medical Center. A member of the faculty of Yale School of Medicine since 2007, Dr. Chandra is an Associate Professor in the Departments of Neurology and Neuroscience. Dr. Chandra’s laboratory explores two inter-related themes –synapse maintenance and neurodegeneration. In particular, the lab investigates Parkinson’s disease genes and risk alleles that encode synaptic proteins and how they impact synaptic structure, function, and neuronal health. The long-term goal of the research in the Chandra lab is to parlay a basic understanding of Parkinson’s disease genes for the development of early disease-modifying therapies.  Tuesday, April 17th at 06:00 PM Eastern Standard Time (EST):

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