The Sabatini Lab (@SabatiniLab) profile picture

The Sabatini Lab

@SabatiniLab

Neuroscience laboratory at Harvard Medical School led by Bernardo Sabatini.

sabatini.hms.harvard.edu/
Joined May 2014
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Bernardo Sabatini (@blsabatini) profile picture
Bernardo Sabatini@blsabatini12 Nov 2019
Our latest work is now on available. Cell-type specific asynchronous modulation of PKA by dopamine during reward based learning biorxiv.org/content/10.1101/… This is collaborative work led by no-twitter MD/PhD student Suk Joon Lee with @yaochen20 @LinTianLab @SabatiniLab
Cell-type specific asynchronous modulation of PKA by dopamine during reward based learning

Cell-type specific asynchronous modulation of PKA by dopamine during reward based learning

Canonical reinforcement learning models postulate that dopamine neurons encode reward prediction error (RPE) and provide a teaching signal to striatal spiny projection neurons (SPNs) in the form of...

biorxiv.org
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The Sabatini Lab retweeted
Bernardo Sabatini (@blsabatini) profile picture
Bernardo Sabatini@blsabatini12 Nov 2019
And, I think, our final @sabatinilab paper with @neurodev_lab (Rui Peixoto) who is now leading his own lab at U. Pitt. Also involves striatal PKA! Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B−/− Mice cell.com/cell-reports/fullte…

Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B−/− Mice

Peixoto et al. show that the onset of behavioral deficits in Shank3B−/− mice occurs during early postnatal development and that these can be ameliorated by reducing the glutamatergic synaptic drive...

cell.com
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The Sabatini Lab retweeted
Bernardo Sabatini (@blsabatini) profile picture
Bernardo Sabatini@blsabatini13 Nov 2018
Big effort by @ajgrange and company from @SabatiniLab on cortical cholinergic VIP cells is now on biorxiv biorxiv.org/content/early/20…
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The Sabatini Lab retweeted
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Bernardo Sabatini@blsabatini6 Dec 2017
The free link to the final version of our Gaq-GPCR->PKA paper is now available at Neuron. Please share. Link gives free downloads and access. authors.elsevier.com/a/1WAiY…
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