Bacterial geneticist @HumboldtUni studying assembly and function of a fascinating nanomachine - the bacterial flagellum
Berlin, Germany
Joined December 2016
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Marc Erhardt retweeted
Salmonella-phage networks
Profiling >1,000 global Salmonella-phage interactions reveals layered resistance &high contribution of surface architecture to defense. Discover AppA, which blocks phage DNA packaging via mimicry of terminase assembly interface
cell.com/cell-host-microbe/f…
Marc Erhardt retweeted
The final version of our manuscript on TnSeq in bacteriophages (“HIDEN-SEQ”) is out today – if you have an interesting phage phenotype and want to know the underlying genetic basis, this one is for you! 1/3
Marc Erhardt retweeted
Congratulations to first author @AritzRoa for his amazing work on how T4 delivers its genome and blocks other phages from injecting theirs 🥳 Check out his beautiful movie📽️ Thanks to all authors and collaborators MLNielsen and @AHarms485 tinyurl.com/2kvva646 #cryoEM #phage
Marc Erhardt retweeted
#MicrobiologyMonday: The bacterial flagellum is built through a hierarchical assembly process and powered by a dynamic motor capable of astonishing speeds. What's new in our understanding of these complex nanomachines? Find out in #MMBRJournal: asm.social/2HB
ALT Structures of the bacterial flagellum of Salmonella enterica
Marc Erhardt retweeted
A beautiful example of evolutionary innovation: Bacterial chemoreceptor was "reprogrammed" in pathogenic E. coli to control expression of flagellar genes instead of signalling through the chemotaxis pathway. embopress.org/doi/full/10.10…
Marc Erhardt retweeted
Out Now! The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation bit.ly/4nqcNe9 #Microbiology #Bacteria #Flagellum
Marc Erhardt retweeted
Cold Spring Harbor Laboratory - absolutely humbled by the beauty of this place and the ubiquitous spirit of the Delbrück "phage group" era 🧬🌊🦪
Marc Erhardt retweeted
Exited to share our preprint on the structure of a Salmonella contractile injection system 🥳 Wonderful work by first author @Rooshanie Ejaz and @CloudyKielkopf, @freddie__martin, @HangryHobbit, @RebrovaEva, great collab with @Salmo_Lab
@UCPH_CPR #cryoem
shorturl.at/QHLpm
Marc Erhardt retweeted
And here it is, the completed BASEL collection finally published as early access in @PLOSBiology - see the thread for more details. 🤗🧬🎣
Marc Erhardt retweeted
Join us and @Salmo_Lab to explore phage-bacteria interactions, with a strong focus on microscopy techniques. Looking for a motivated PhD student!
🔬 Interested? Apply here 👉 [nature.com/naturecareers/job…]
🔄 Please re-share to spread the word!
Marc Erhardt retweeted
With @jrpenades, we challenged AI co-scientist @GoogleAI to generate hypotheses. In just 2 days, it recapitulated our unpublished, experimentally confirmed mechanism for how cf-PICIs spread between bacterial species! 🤯 @imperialcollege @FlemingCentre
tinyurl.com/3byyaeh2
Marc Erhardt retweeted
Our paper out @Nature: CARD domains mediate anti-phage defense in bacterial gasdermin systems
CARDs are essential for caspase recruitment in inflammasome activation. We now find them in bacterial immune systems
Congrats @TanaWein! Thanks Kranzusch lab!
tinyurl.com/CA88DD
Marc Erhardt retweeted
Internationales Forschungsteam beschreibt erstmals die Struktur und Funktionsweise des Zorya-Systems, eines hochspezialisierten antiviralen Schutzmechanismus gegen Bakterien
nature.com/articles/s41586-0…
@Salmo_Lab @__jphilipp
Bild: Frederick J.O. Martin/ Universität Kopenhagen
Marc Erhardt retweeted
🦠 Neues bakterielles #Immunsystem entschlüsselt: Ein internationales Forschungsteam um @Salmo_Lab & @__jphilipp der #HumboldtUni beschreibt nun erstmals die #Struktur und #Funktionsweise des Zorya-Systems in der Fachzeitschrift @Nature!
Mehr Infos 👉 hu-berlin.de/de/pr/nachricht…
ALT 3-D-Modell des bakteriellen Viren-Abwehrsystems Zorya Foto: Frederick J.O. Martin/ Universität Kopenhagen
Marc Erhardt retweeted
Thrilled to share that our collaborative work, led brilliantly by @HaidaiHu, is now published in @Nature! Huge thanks to the incredible @NMITaylorLab team - it was a joy to work with you. Grateful to @Salmo_Lab, @SimonJacksonNZ, and @AHarms485 for their invaluable contributions!
Very happy our paper on Zorya anti-phage defense system is now published in
@Nature! 🥳 Big congrats to first authors
@HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab
and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
Marc Erhardt retweeted
Evolutionary necessity for immune innovation harnessed components of the bacterial flagellar motor into a wild defense system - Zorya
One of the most intriguing and sophisticated bacterial defense systems out there
Congratulations Nicholas Taylor and colleagues!
Very happy our paper on Zorya anti-phage defense system is now published in
@Nature! 🥳 Big congrats to first authors
@HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab
and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
Marc Erhardt retweeted
Beautiful work on a crazy anti-phage system!
Very happy our paper on Zorya anti-phage defense system is now published in
@Nature! 🥳 Big congrats to first authors
@HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab
and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
Marc Erhardt retweeted
Very happy our paper on Zorya anti-phage defense system is now published in
@Nature! 🥳 Big congrats to first authors
@HaidaiHu and @__jphilipp and all other authors! Wonderful collab with @Salmo_Lab
and @SimonJacksonNZ #cryoEM @UCPH_CPR @koebenhavns_uni nature.com/articles/s41586-0…
Marc Erhardt retweeted
Bacterial small RNA makes a big impact for gut colonization
Monzel & Desai @LIH_Luxembourg highlight work of @MoualiYoussef @StrowigLab IDing SrcF, sRNA from S. copri that promotes colonization by regulating bacterial degradation of dietary carbohydrates
cell.com/cell-host-microbe/a…
Marc Erhardt retweeted
Gratulation! 🙌 Das Forschungsvorhaben RESYDE, geleitet von #HU-Prof. Dr. Kerstin Kaufmann, erhält einen @ERC_Research Synergy Grant für die Entschlüsselung komplexer Musterbildungsprozesse in biologischen Systemen in Höhe von 10 Millionen Euro. #ERCSyG
👉hu-berlin.de/de/pr/nachricht…
ALT Das Team um HU-Biologin Kerstin Kaufmann erhält einen ERC Synergy Grant Foto: Stefan Klenke