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Schwer Lab

@SchwerLab

Our lab studies DNA repair and genomic stability in the contexts of development, cancer, and aging of the brain

 University of California, San Francisco
schwerlab.ucsf.edu/
Joined February 2019
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  • Followers355
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Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)Photo by Schwer Lab (@SchwerLab)
Excited to share my work at #cellbio2023 about DNA double-strand breaks in neurons. Let's talk at my poster on Monday and don't miss my talk on Wednesday!
Image from Laura Cheradame (@LauraCheradame1)
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What a beautiful day for our inaugural symposium! Thank you to our keynote speakers, faculty, and trainees for making it a success. #aging @UCSFAging @deyoungmuseum
Image from UCSF Bakar Aging Research Institute (@UCSFAging)
Image from UCSF Bakar Aging Research Institute (@UCSFAging)
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PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression biorxiv.org/cgi/content/shor… #biorxiv_cancer
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Our new paper on how stem cells coordinate transcription and DNA replication to protect genome integrity is out now in @NatureSMB: nature.com/articles/s41594-0…. More info ⬇️. @UCSF, @UCSFstemcell, @UCSFUrology, @UCSFCancer, @UCSF_ObGynRS
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It’s a tremendous pleasure to host a joint workshop of our ⁦@dfg_public⁩ research unit FOR 5504 and the NIA PPG on genome instability with exciting keynote lectures by Laura Niedernhofer seen here and ⁦@SchwerLab⁩ and ⁦@George_Garinis⁩
Image from Björn Schumacher (@schumacherbj)
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Congrats class of 2023!🎉 The countdown to graduation is on. Remember to include @UCSF in your epic celebrations because we're ready to shine the spotlight on your victorious moments!📸🎓 #UCSFGrads
Text- Congrats Class of 2023! # UCSFGrads Image: Two women in caps and cowns taging a selfie with their dipoma

ALT Text- Congrats Class of 2023! # UCSFGrads Image: Two women in caps and cowns taging a selfie with their dipoma

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Congratulations @kevansf @UCSF, winner of the 2023 @theNASciences Award for Scientific Discovery for pioneering breakthroughs in chemical biology to advance cancer therapy! To be awarded at the 160th NAS Annual Meeting! nasonline.org/programs/award… #UCSFProud #NASaward #academia #HHMI
Kevan Shokat of UCSF awarded the 2023 NAS Award for Scientific Discovery

ALT Kevan Shokat of UCSF awarded the 2023 NAS Award for Scientific Discovery

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Are you an undergrad thinking about grad school in a biology-related field? Do you identify as a member of a historically excluded group in STEM, grow up with in a disadvantaged background, or experience an ongoing disability? Come join our amazing @UCSF_PROPEL community!🧵
UCSF PROPEL (@UCSF_PROPEL) profile pictureUCSF PROPEL@UCSF_PROPEL22 Oct 2022
Incredibly excited to announce the 2023 @UCSF Virtual Matchmaking Event for Postbaccalaureate Scholars on Feb 1, 2023! Register by Jan 6! Come meet 6+ faculty with shared research interests, and join our amazing and thriving community! Visit justice.ucsf.edu for more info
Image from UCSF PROPEL (@UCSF_PROPEL)
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Applicants interested in learning more about the UCSF Neuroscience PhD program check out this link to sign up for our grad fair on 10/24. neurograd.ucsf.edu/graduate-…
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REVIEW | R Mostoslavsky, R Boon & G Silveira (@harvardmed) explore how nuclear #metabolism regulates compartamentalization, #epigenetics & cell physiology. #TBT 🔙 nature.com/articles/s42255-0…
Nuclear metabolism and the regulation of the epigenome

Nuclear metabolism and the regulation of the epigenome

Nature Metabolism - Cellular metabolism has emerged as a major biological node governing cellular behaviour. In their review, Boon et al. explore the mechanisms that maintain nuclear metabolic...

nature.com
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Schwer Lab retweeted
QBI (@QBI_UCSF) profile picture
QBI@QBI_UCSF27 Sep 2022
As part of the #QBIChemBio22 Symposium today, @jadoudna, Nobel Laureate, co-inventor of #CRISPR-Cas9 & Professor at @UCSF/@UCBerkeley will participate in a Twitter Space hosted by Jason Gestwicki. Tune in at 1:30 PT to hear about her work! qbi.ucsf.edu/twitter-space-d…
Image from QBI (@QBI_UCSF)
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Our postprint on mechanisms by which dopamine engages PFC astrocytes is out! Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors cell.com/cell-reports/fullte…
Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

Dopamine activates astrocytes in prefrontal cortex via α1-adrenergic receptors

Pittolo et al. demonstrate that the neuromodulator dopamine targets astrocytes, a type of brain cell, via receptors specific to another neuromodulator—norepinephrine. This study provides groundwork...

cell.com
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Everyone is at some level of risk to develop cancer in their lifetime. Check out the risk factors below that may indicate you should consider genetic testing! via @MyGeneCounsel #BRCA #cancer #genetics #hereditarycancer #hereditarycancerweek
Image from Amy Byer Shainman (@BRCAresponder)
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Next Monday, September 26th: @UCSF Cancer Center Special Seminar with @nussenza Andre Nussenzweig, PhD, NIH Distinguished Investigator, Laboratory of Genome Integrity, National Cancer Institute | "DNA demethylation and instability in post-mitotic cells"
Schwer Lab (@SchwerLab) profile pictureSchwer Lab@SchwerLab13 Sep 2022
Looking forward to Andre's @nussenza visit and seminar at @UCSF in a few weeks:
Image from Schwer Lab (@SchwerLab)
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I'm looking forward to speaking at this open virtual conference on Friday, in a session focused on cell types and brain regions. Check out the full agenda: bit.ly/3dYYo9k
Image from Kira Poskanzer (@KiraPoskanzer)
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Fun and exciting collaboration with ⁦@wanghychemistry⁩, Jack Taunton, ⁦and @TheBlanchardLab⁩ on the mechanisms of targeting the eEF1A translation factor in cancer with a new compound, SRA-3. nature.com/articles/s41557-0…
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the...

Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the...

Nature Chemistry - The total synthesis and complete stereochemical assignment of the cyclic peptide natural product SR-A3—which has potential as a cancer therapeutic—has now been...

nature.com
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Fascinating work on how ribosome composition changes during stem cell differentiation impact the instructions underlying body patterning. Congrats Naomi, ⁦@mbarnalab⁩ and team! nature.com/articles/s41467-0…

A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production

Nature Communications - How ribosomes differ in composition and function to regulate gene expression is poorly understood. Here, the authors show that ribosome composition changes during stem cell...

nature.com
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Can't wait! An amazing lineup including our outstanding PhD candidate Mikayla Richter @UcsfPspg ! events.bizzabo.com/404869/ag…
Cancer Neuroscience

Cancer Neuroscience

Be part of a groundbreaking scientific event that will integrate neuroscience and cancer biology to spur a wave of innovation in cancer research and treatments. Advanced Biology and The University of...

events.bizzabo.com
Gutmann Laboratory (@GutmannLab) profile pictureGutmann Laboratory@GutmannLab18 Sep 2022
Looking forward to this exciting meeting. #cancer #neuroscience. Can't wait!!! soc-neuro-onc.org/SNO/Events…
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We are excited to celebrate our Latinx Heritage this month with our executive board member @ruru_rocks15 for a "pastelón" cook along night! Join @UCSF_MRC and the @UCSF community as we learn more about this Puerto Rican delicacy! #SACNAS #PuertoRico
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Pleased to be @WhiteHouse for discussion of Biden’s Executive Order on National Biotechnology & Biomanufacturing Initiative -> translate bioscience discoveries/tech into medical breakthroughs, stronger US supply chains & more, valued at $30trillion by 2030 whitehouse.gov/briefing-room…
Image from Keith Yamamoto (@kryamamoto)
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