Pediatric Hematologist/Oncologist/BMT @Cleveland Clinic Children's; opinions my own
Cleveland, OH
Joined October 2012
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seth rotz retweeted
Excited to share my Targeted Oncology interview on gaps in chronic GVHD screening and the need for more standardized approaches to early recognition.
Grateful to the ENGRAFT team, my mentors @SethRotz & @ClevelandClinic @CleClinic_PHO
targetedonc.com/authors/lail…
seth rotz retweeted
Huge congrats to Dr @SethRotz @SoheiKuriMDPhD @ScottLundyMDPhD Dr Hannick @RabiHannaMD and team for the Hyundai Hope on Wheels grant! @CleClinicUro Center for Male Fertility @drjkaouk are proud to support this important work & our pediatric cancer warriors 🙏 @hopeonwheels
seth rotz retweeted
Thank you so much, Dr. Bole, for your support! We are incredibly grateful to @hopeonwheels and excited to advance this work to help preserve future fertility for pediatric cancer patients.
seth rotz retweeted
I am THRILLED to announce my new position as Market Chief of Research for Cleveland Clinic Abu Dhabi! My family and I have relocated to the UAE and met the exceptional team I have the privilege of joining to strategically expand the @CCAD research portfolio and transform medicine
seth rotz retweeted
Thank you, everyone, for attending our January 2025 design session! We're thrilled to have our project picked and can't wait to see you all this summer. Special shoutout to our Engraft Olympic champions, “You down with A-P-P?” — stellar teamwork! 🎉
seth rotz retweeted
🚨PublicationAlert🚨 How I Treat Sickle Cell Disease with Gene Therapy, published online (authors.elsevier.com/a/1kKhU… ) and in print in @BloodJournal
Many thanks to @DrAlexisThompsn @jkw4444 @LakshmananKris7 @shal34982692 @BMTriplettMD and @allistair_2001 for their inputs 🙏
seth rotz retweeted
Tom Hamilton, the radio announcer for #Indians / #Guardians games for 35 years and counting on Wednesday was selected by the Baseball Hall Fame for induction in Cooperstown this summer. His emotional reaction is priceless.
seth rotz retweeted
Fred Hutch’s @msorror presents the latest findings on a new health assessment model called CHARM, which helps health care teams predict which patients will survive transplantation. #ASH24 fredhutch.org/en/news/center…
seth rotz retweeted
Original Article: Blinatumomab in Standard-Risk B-Cell Acute Lymphoblastic Leukemia in Children (AALL1731) nej.md/49CVkc1
#ASH24 | @ASH_hematology
ALT The comparisons of 3-year disease-free survival (Panel A), overall survival (Panel B), and cumulative incidence of relapse (Panel C) in the overall randomized cohort, among patients who underwent randomization and had an average risk of relapse, and among those who underwent randomization and had a high risk of relapse.
ALT Forest plot of disease-free survival in various subgroups as assessed by restricted mean survival time estimates.
seth rotz retweeted
Impressive results about Exa-Cel in TDT from @VertexPharma at # ASH
- 54 patients
- 98% (53/54) had achieved Transfusion free x12 months
- the remaining patient is free of RBC Tx for at least 8 months
Similar results about safety and efficacy in #SCD
seth rotz retweeted
BEACON study initial data @BeamForAll IN #AS24
- BASE editing in Hgb1/2 for #SCD :7 patients
- less collection cycles
- faster engraftment in ANC (17 days) and PLT (19 days)
- one death
- high level of hgb F (>60%) with improvement in total hemoglobin and less hemolysis
seth rotz retweeted
1/ This is the next chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord. 🧵nature.com/articles/s41586-0…
seth rotz retweeted
No new safety concerns were identified with daratumumab treatment in children and young adults with B-cell ALL or T-cell ALL/LL. ow.ly/C42E50UckmH #lymphoidneoplasia
seth rotz retweeted
Leveraging Oncology Treatments for Vascular Anomalies my.clevelandclinic.org/podca… via @clevelandclinic
seth rotz retweeted
Menin inhibitor approved for relapsed or refractory ALL with (KMT2A) translocation in adult and pediatric patients 1 year and older.
FDA approves revumenib for relapsed or refractory acute leukemia with a KMT2A translocation fda.gov/drugs/resources-info…
seth rotz retweeted
Key factors increasing the chance of pregnancy were younger age at HCT, nonmalignant disease, no TBI or dose <8 Gy and RIC/NMA conditioning
@BloodJournal - Hope for motherhood: pregnancy after allogeneic #BMT ashpublications.org/blood/ar…
seth rotz retweeted
Engraft was awarded the DENNIS CONFER INNOVATE
AWARD from the NMDP. Congratulations, Engraft! | The ONE Forum 2024 youtu.be/mfr2o878Vjo?si=oasW… via @YouTube
