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The Shechner lab in UW Pharmacology. We study Noncoding RNAs and cellular architecture. He/His/Him. All comments are my own. @ShechnerLab.bsky.social

Seattle, WA
Joined September 2018
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New (to you?) preprint alert! Can protein-coding mRNAs "moonlight" as nuclear-architectural RNAs? Our revised preprint uncovers how nascent TTN RNA organizes a specialized nuclear compartment in cardiac cells—and how its disruption may contribute to heart disease. A thread! 🧵
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And that's a wrap! I hope you've enjoyed this thread and give our preprint a read. Let us know what you think! tinyurl.com/45ds5ccs
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One more shout-out to my longtime friend and collaborator, @berteroale, and his amazing team! This was a deeply collaborative project, with Ale's group driving many of the computational and functional analyses that brought the story together. Couldn't have done it without you!
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