Stewart Jeromson (@StewartJeromson) header
Stewart Jeromson (@StewartJeromson) profile picture

Stewart Jeromson

@StewartJeromson

Scientist interested in Exercise and metabolism.

 Vancouver, BC
Joined January 2013
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Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)Photo by Stewart Jeromson (@StewartJeromson)
If you haven't already, check out our new work from #HAMOLab on regulation of carnitine uptake in muscle. ncbi.nlm.nih.gov/pubmed/2829…
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A large and talented team from @UTHealthBarshop @uthealthbarshop.bsky.social bring you today's paper, Low-frequency ultrasound reverses insulin resistance and diabetes-induced changes in the muscle transcriptome in aged mice (Erik Marchant et al.): ow.ly/7TcU5101tgf
Image from AJP-Endocrinology and Metabolism (@AJPEndoMetab)
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Craig A. Goodman (@CraigAGoodman1) profile picture
Craig A. Goodman@CraigAGoodman1Oct 27
Adipocyte Lipolysis is a Determinant of Skeletal Muscle Size During Fasting and Feeding journals.physiology.org/doi/…
Adipocyte Lipolysis is a Determinant of Skeletal Muscle Size During Fasting and Feeding | American...

Adipocyte Lipolysis is a Determinant of Skeletal Muscle Size During Fasting and Feeding | American...

Intermittent fasting (IF) can lower fat mass, but also muscle mass. The mechanisms governing tissue partitioning during fasting remain unclear. During fasting, adipose-derived fatty acids from...

journals.physiology.org
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Kevin Murach (@KevinMurachPhD) profile picture
Kevin Murach@KevinMurachPhDOct 15
“A Hypertrophic Stimulus Drives Age-Dependent Transcript Isoform Switching With and Without Differential Gene Expression in Skeletal Muscle” by @PJKoopmansPhD w/@AhmedIsmaeelPhD @yuan_wen16220 and Nelson lab at U of A @AgingCell onlinelibrary.wiley.com/doi/… #myotwitter
A Hypertrophic Stimulus Drives Age‐Dependent Transcript Isoform Switching With and Without Differ...

A Hypertrophic Stimulus Drives Age‐Dependent Transcript Isoform Switching With and Without Differ...

A combined analysis of short-read and long-read RNA-seq demonstrates reduced isoform switching after an acute hypertrophic stimulus in aged muscle and identifies age-dependent isoforms that may not...

onlinelibrary.wiley.com
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Henning Wackerhage (@HeWaHippo) profile picture
Henning Wackerhage@HeWaHippoSep 28
Just out! A fantastic around the world collaboration with my teacher Hermann Heck showing that Alois Mader’s model can simulate 10 phenomena of human energy metabolism. The link is here: pnas.org/doi/10.1073/pnas.25…. Here is the software: metabolisim.org/
Image from Henning Wackerhage (@HeWaHippo)
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Nature Metabolism (@NatMetabolism) profile picture
Nature Metabolism
@NatMetabolismSep 25
#Throwback REVIEW | Alexander S. Banks et al A consensus guide to preclinical indirect calorimetry experiments nature.com/articles/s42255-0…
A consensus guide to preclinical indirect calorimetry experiments

A consensus guide to preclinical indirect calorimetry experiments

Nature Metabolism - The authors highlight inconsistencies and divergencies in the literature reporting data on indirect calorimetry for studies on whole-body energy homeostasis, and propose...

nature.com
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htw (@heniek_htw) profile picture
htw@heniek_htwSep 25
New review maps the adipose–liver axis: FFAs released by lipolysis signal via PPARα, HNF4α, and organelle remodeling (mitochondria, ER, peroxisomes, LDs) to balance lipid oxidation, storage, and export. Chronic FFA overload drives MASLD. sciencedirect.com/science/ar…
Image from htw (@heniek_htw)
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Ildus I. Ahmetov (@SportsGenomics) profile picture
Ildus I. Ahmetov@SportsGenomicsSep 18
151 genes linked to strength preservation during calorie restriction-induced weight loss onlinelibrary.wiley.com/doi/…
Biological Pathways of Strength Preservation During Calorie Restriction‐Induced Weight Loss Among...

Biological Pathways of Strength Preservation During Calorie Restriction‐Induced Weight Loss Among...

Analysis workflow for identifying strength-associated pathways and genes using the CALERIE data set.

onlinelibrary.wiley.com
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Cell Reports (@CellReports) profile picture
Cell Reports@CellReportsSep 17
Anticipatory metabolic regulation drives the distinct and improved metabolic state of caloric restriction compared to Fasting-Refeeding cycles dlvr.it/TVXDSm
Anticipatory metabolic regulation drives the distinct and improved metabolic state of caloric...

Anticipatory metabolic regulation drives the distinct and improved metabolic state of caloric...

Velingkaar et al. demonstrate that metabolic adaptation during caloric restriction is driven by more than prolonged fasting. They show that caloric restriction engages anticipatory, circadian-regul...

cell.com
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Cell Metabolism (@Cell_Metabolism) profile picture
Cell Metabolism@Cell_MetabolismSep 9
Protein restriction and the hallmarks of aging: A coordinated physiological adaptive response? dlvr.it/TVPRz9
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Nick Krontiris (@nick_krontiris) profile picture
Nick Krontiris
@nick_krontirisSep 5
The aim of this review is to broadly introduce sports and exercise scientists to fat metabolism and the function of white, beige and brown adipose tissue in the context of exercise.
Image from Nick Krontiris (@nick_krontiris)
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Daniel J Drucker (@DanielJDrucker) profile picture
Daniel J Drucker@DanielJDruckerAug 21
The weight loss proteome in mice nature.com/articles/s42255-0… @NatMetabolism
Multi-organ proteomic atlas of obesity regression in male mice

Multi-organ proteomic atlas of obesity regression in male mice

Nature Metabolism - A multi-organ proteomics resource of diet-induced obesity and its regression in male mice, spanning 15 organs and 4 timepoints, highlights systemic changes as well as...

nature.com
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Exercise-induced myokines in metabolic regulation: mechanisms, mimetics, and translational potential link.springer.com/article/10…
Image from Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM (@agingdoc1)
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New study: Resting metabolism fell more than predicted during weight loss—even in athletes who gained fat-free mass. 💪📉 Preserving muscle ≠ preventing metabolic adaptation. nature.com/articles/s41366-0…
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Craig A. Goodman (@CraigAGoodman1) profile picture
Craig A. Goodman@CraigAGoodman1Aug 22
Exercise and Fat: A Primer link.springer.com/article/10…
Exercise and Fat: A Primer

Exercise and Fat: A Primer

Sports Medicine - Open - Over the past 25 years, adipose tissue has emerged as an organ comprising nearly 20 major cell types, including three types of adipocyte subtypes: white, brown,...

link.springer.com
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Michalis Nikolaidis (@mg_nikolaidis) profile picture
Michalis Nikolaidis@mg_nikolaidisAug 22
1/13 How many calories does it take to build 1 kg of muscle? The question is straightforward but, as far as we can tell, it has not yet been answered quantitatively. biorxiv.org/content/10.64898…
The Energetic Cost of Building Human Skeletal Muscle

The Energetic Cost of Building Human Skeletal Muscle

The energetic cost of building human skeletal muscle has never been explicitly calculated or measured. We developed a quantitative bottom-up accounting model that integrates human skeletal-muscle...

biorxiv.org
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Javier Gonzalez (@Gonzalez_JT) profile picture
Javier Gonzalez@Gonzalez_JTAug 7
Does fuel use during exercise influence how much you eat? Substrate availability was altered using carbohydrate & niacin. Despite clear effects on substrate oxidation, GLP-1, ketones and VLDL-TG, we found not evidence for differences in energy intake. 🔗 jn.nutrition.org/article/S00…
Image from Javier Gonzalez (@Gonzalez_JT)
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The value of targeting ketone body metabolism in inflammatory and autoimmune diseases link.springer.com/article/10…
Image from Agingdoc🩺Dr David Barzilai🔔MD PhD MS MBA DipABLM (@agingdoc1)
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Aging Science News (@AgingBiology) profile picture
Aging Science News
@AgingBiologyAug 18
The GLP-1–Mitochondria Axis in Metabolic Aging onlinelibrary.wiley.com/doi/…
The GLP‐1–Mitochondria Axis in Metabolic Aging

The GLP‐1–Mitochondria Axis in Metabolic Aging

Glucagon-like peptide-1 receptor agonists engage AMPK–PGC-1α signaling to remodel mitochondrial biogenesis, dynamics, and quality control, but downstream effects are context-dependent and tissue-sp...

onlinelibrary.wiley.com
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Delayed molecular aging, preservation of energy metabolism and enhanced exercise response in exercise-trained human muscle nature.com/articles/s43587-0…
Image from David Bishop (🦋 also bluespotscience.bsky.social) (@BlueSpotScience)
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Function (@APS_Function) profile picture
Function@APS_FunctionAug 14
Researchers find increased senescent #macrophage burden in muscle & #knee in preclinical #ACL injury model, and provide evidence that treatment with #senolytics is an effective strategy to mitigate posttraumatic #osteoarthritis severity. ow.ly/VpoN50ZzPlR
Image from Function (@APS_Function)
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