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Tepe Group

@Tepe_Lab

Synthesis of small molecules for proteasome regulation, total synthesis of natural products, and methodology development at Michigan State University.

 East Lansing, MI 48824
tepegroup.chemistry.msu.edu
Joined June 2021
  • Tweets55
  • Following112
  • Followers175
Presenting the latest Doctors from the Tepe group! Congratulations Dr Fiolek, Dr Staerz, and Dr Vanecek. We wish you all the best in your future endeavors!
Image from Tepe Group (@Tepe_Lab)
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#TotalSynthesis of Nagelamide W by Dare E. George @dare_george_ and Jetze J. Tepe @jetze_tepe @Tepe_Lab at @MSUChem in @JOC_OL pubs.acs.org/doi/10.1021/acs…
Image from Total Synthesis (@TotalSynthesis)
Image from Total Synthesis (@TotalSynthesis)
Image from Total Synthesis (@TotalSynthesis)
Image from Total Synthesis (@TotalSynthesis)
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Congratulations Evan. Good job on this!
Evan Savelson (@esavelson) profile pictureEvan Savelson@esavelson15 May 2023
I'm happy to share my paper on the synthesis of colensolide A. I had always wanted to try a Curtius rearrangement, and I got ample opportunity to do so while working on this molecule! doi.org/10.1021/acs.orglett.…
Accessing Highly Oxidized Imidazolidinone Cores via a Curtius Rearrangement: Total Synthesis of...

Accessing Highly Oxidized Imidazolidinone Cores via a Curtius Rearrangement: Total Synthesis of...

Abstract. The hydroxytetrahydropyrrolo-imidazolidinone (HTHP-I) core present in colensolide A is a synthetically intriguing scaffold as a result of its hig

pubs.acs.org
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Great paper using the Azure 300 from @Tepe_Lab at University of Michigan 👏
proteostasis_papers (@ProteostasisP) profile pictureproteostasis_papers@ProteostasisP8 May 2023
Development of a Cell-Based AlphaLISA Assay for High-Throughput Screening for Small Molecule Proteasome Modulators dlvr.it/SnjPyH
Image from proteostasis_papers (@ProteostasisP)
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Introducing the new Doctor from our group! Congratulations Dr. Fiolek on completing your PhD. We are proud of you and we will miss you. @MSUChem #chemistry #ChemicalBiology #organic #PhD
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Congratulations @Konika0805
Konika (@Konika0805) profile pictureKonika@Konika08054 Mar 2023
Presented my PhD thesis in 3 minutes. Won the second prize 🏆 Thank you #cogsmsu for organizing the 3MT competition. #MSUChem P.S. It’s hard to present 4 year project in 3 mins😂
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White elephant / Ugly sweeter by the Tepe lab. What a fun day😂 #chemistry #medchem @MSUChem @MSUNatSci
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Congratulations to @Konika0805 who just received graduate fellowship to promote inclusion, diversity and equity, and accessibility (IDEA) in STEM in Chemistry from CNS. We are proud of you. #IDEA @MSUnews @MSUChem
Image from Tepe Group (@Tepe_Lab)
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We are excited to share our latest article on the synthesis of pyrazoles and pyridines from epoxide pubs.acs.org/doi/10.1021/acs…. Congrats to @shafaat_mehedi and @dare_george_ for teaming up on this. #organicchem #heterocyclic @ACSPublications @MSUChem
Sc(OTf)3‑Mediated One-Pot Synthesis of 3,4-Disubstituted 1H‑Pyrazoles and 3,5-Disubstituted...

Sc(OTf)3‑Mediated One-Pot Synthesis of 3,4-Disubstituted 1H‑Pyrazoles and 3,5-Disubstituted...

Abstract. Here, we report the synthesis of 3,4-disubstituted 1H-pyrazoles and 3,5-disubstituted pyridines from the reaction of epoxides with hydrazine and

pubs.acs.org
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Congratulations to the latest Dr. in town. We are proud of your accomplishments @GraceHubbell2 and we will miss you. Good luck in your next career. #PhD #chemistry @MSUChem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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#NewGroupPhoto of the Tepe Lab. @MSUChem #organicchem #medchem #biochem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Tepe Group retweeted
Daniel (@DanCG_Chem) profile picture
Daniel@DanCG_Chem16 Sep 2022
Replying to @Tepe_Lab
@Tepe_Lab needed to compare cyclohexane drawing strategies #ChemTwitter
Image from Daniel (@DanCG_Chem)
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Check out our new publication on the development of a Rh(III)-catalyzed method to access urea-fused dihydroisoquinolone scaffolds from benzohydroxamates and N-Acyl-imidazol-2-one. pubs.acs.org/doi/10.1021/acs… Congratulations @GraceHubbell2 on this great work. @JOC_OL @ACSPublications
Rh(III)-Catalyzed C–H Activation/Annulation of Benzohydroxamates and 2‑Imidazolones: Access to...

Rh(III)-Catalyzed C–H Activation/Annulation of Benzohydroxamates and 2‑Imidazolones: Access to...

Abstract. A Rh­(III)-catalyzed C–H activation/annulation with an imidazolone as alkene partner is reported to access dihydroisoquinolone-fused imidazolin-2

pubs.acs.org
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Allison gave an oral presentation on “20S proteasome activation protects against proteasome impairment by dipeptide repeat proteins implicated in the disease progression of ALS” during the last ACS Conference in Chicago. #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Tepe Group retweeted
Tepe Group (@Tepe_Lab) profile picture
Tepe Group@Tepe_Lab25 Aug 2022
Replying to @esavelson
@esavelson gave a poster presentation at ACS conference in Chicago on “Accessing the indole-oxazole scaffold: A one-pot approach and its application in natural product synthesis”. #ACSFall2022 #ACSChicago @MSUChem
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Tepe Group retweeted
Tepe Group (@Tepe_Lab) profile picture
Tepe Group@Tepe_Lab25 Aug 2022
Replying to @Konika0805
@Konika0805 gave a poster presentation on her work on the “Synthesis of pyrrolopiperazinone scaffold using novel routes: Application to the total synthesis of bromopyrrole alkaloids” at ACS conference in Chicago. #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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I enjoyed presenting my work at both Sci-Mix and Total Synthesis poster symposiums. Thank you @Tepe_Lab @MSUChem #ACSFall2022 #ACSChicago
Tepe Group (@Tepe_Lab) profile pictureTepe Group@Tepe_Lab24 Aug 2022
Replying to @dare_george_
@dare_george_ gave his poster presentation on “Progress in Total Synthesis of Nagelamide W” at ACS Conference in Chicago. #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Kyra gave her poster presentation on “Total Synthesis of Tulongicin and Related analogues” at ACS poster presentation yesterday I’m Chicago. #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
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Sophia Staerz @zestarrz giving her poster presentation at ACS Conference Chicago on “Development of a Cell-Based AlphaLISA Assay and Utilization in a High-Throughput Screen for Small Molecule Proteasome Enhancers”. #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
Image from Tepe Group (@Tepe_Lab)
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Watch out for Tepe’s lab as we all give our talks and poster presentations! #ACSFall2022 #ACSChicago @MSUChem
Image from Tepe Group (@Tepe_Lab)
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