
PhD Student in the Lab of @ShivKSingh6
Göttingen, Germany
Joined June 2020
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We are thrilled to contribute this research highlight about the findings of Jbara et. al. to Nature Signal Transduction and Targeted Therapy! @sigtrans_sttt @ShivKSingh6
doi.org/10.1038/s41392-023-0…
🧵Follow me to the comments for a short summary…
#PDAC #alternativesplicing
Laura Urbach retweeted
Proud to have contributed to this new work in Science Advances! Congrats to @ShivKSingh6 and team for revealing how TP53 missense mutations fuel plasticity & resistance in PDAC, highlighting the need for combined therapies.🔗 science.org/doi/10.1126/scia…
Laura Urbach retweeted
📢 Happy to share our new study in @ScienceAdvances 🔥
🚨 We explore why pancreatic cancer cells survive after eliminating oncogenic missense TP53 (misp53) mutants, and how they continue to grow despite clinical therapies💊
🧵1/11
👉science.org/doi/10.1126/scia…
Laura Urbach retweeted
📢 Excited to share our study in @NatureComms, previously available on bioRxiv by Klein et al.
👉 rdcu.be/d5q9f
Laura Urbach retweeted
Presented new data on how inflammatory factors affect immune cells phagocytic activity & and had an insightful discussion on prioritizing chemo/radio therapy with anti-inflammatory factors with Prof. Chadan Guha and other radio-oncologists @EinsteinMed, Bronx!
Laura Urbach retweeted
This was the 4. German #PancreaticCancer Research Meeting - An @EKFStiftung Symposium by @kfo_5002 and #CCCN. Congratulations to @krenz_bastian from @Uni_WUE for the @Krebshilfe_Bonn best talk award & Thomas L. Ekstrom from @RBCTStuttgart for the @EmboMolMed best poster award 🎉
Laura Urbach retweeted
Congratulations Dr. Laura Urbach🎓 @UrbachLaura 🎊 You have made me & our lab very proud 👏 We have been lucky to have you in our lab! I m sure you will excel wherever you go!!
#Gänseliesel rituals
@kfo_5002 @yourUMG @rebeccadiya
@frederikepenz @LukasKlein01
@Xueyan__Wu
Laura Urbach retweeted
🎉Excited to be part of the newly formed TRANSCAN @transcanproject team researching the stromal immune epigenome network in #pancreatic cancer vulnerability! Kudos to @AkisPapantonis for pushing this forward. Congratulations to all co-PI involved!
Some good news just in: our lab @yourUMG will be coordinating a newly-minted @transcanproject on #pancreatic cancer aiming at bridging epigenomics with mechanical changes in the tumor niche...
Laura Urbach retweeted
Absolutely thrilled to share my first talk at DPC! Grateful for the opportunity to present our research on BRD4's role in PDAC development and the exciting discoveries we've made. 🧬🔬#IPMN
Had a fantastic time at DPC with so many wonderful talks and posters.
@German_PancClub
Laura Urbach retweeted
Replying to @yourUMG
@yourUMG at the @German_PancClub in Bonn. Many oral talks and many well designed Poster disseminating PhD and MD works of all our research groups. Honored with Poster prizes🥳 @UrbachLaura & Anna Weber and travel Grant @aiko_bockelmann.🤟Successful congress. Thank you Bonn 😍
Laura Urbach retweeted
Congratulations on your well-deserved poster award, Laura!! We're proud of you 🎊 👏
@German_PancClub @UrbachLaura @kfo_5002
🗣️ Let’s talk about missense p53 mutants driving divergent pathways in pancreatic cancer 👩🏼🔬
AG Singh @ShivKSingh6 @LukasKlein01 @rebeccadiya @Xueyan__Wu having a good time at #DPC2024 in Bonn listening to lots of great talks and posters. 👍🏼
@German_PancClub
🗣️ Let’s talk about missense p53 mutants driving divergent pathways in pancreatic cancer 👩🏼🔬
AG Singh @ShivKSingh6 @LukasKlein01 @rebeccadiya @Xueyan__Wu having a good time at #DPC2024 in Bonn listening to lots of great talks and posters. 👍🏼
@German_PancClub
Laura Urbach retweeted
Today is #WorldPancreaticCancerDay - and of course we at CRU5002 and at @yourUMG and @cccn_news are taking part! Find more information here: gccc.umg.eu/weltpankreaskreb…. For more about our work go to: gccc.umg.eu/en/cru-5002/.
Yesterday’s symposium of the @cccn_news at the MHH in Hanover for young cancer scientists was fun! 👩🏼🔬🧬
Besides lots of cool posters and innovative talks I had the pleasure to talk about my PhD project. 🤓
Thanks to the organizers for setting up an excellent meeting. #fightcancer
Laura Urbach retweeted
🟣 Out now just in time for Pancreatic Cancer Awareness Month 🟣
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response via AP1 dichotomy in pancreatic cancer biorxiv.org/cgi/content/shor… #biorxiv_cancer
Laura Urbach retweeted
🧬 Our new study on how "Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response via AP1 dichotomy" is out now on @biorxivpreprint 🎉! Collaborative work of @ShivKSingh6 and @BarbaraGrnwald labs 🧪 Let's dive into the key findings! 🧵
Laura Urbach retweeted
Defended my PhD today 🎉🎉🎉
Thanks @ShivKSingh6, so glad to have stayed (and continue to stay ;)) in your lab - it’s been four awesome years
An outstanding PhD thesis defense by @LukasKlein01 that impressed everyone in attendance. He received a very well deserved 'summa cum laude' @yourUMG Our lab is proud of you 🎊 👏
Presented my PhD data on the #AACRPan23 in Boston! Fruitful discussions and nice feedback from a lot of listeners. It’s been a pleasure!👩🏼🔬😊
Proud to be part of the Singh Lab @ShivKSingh6 and CRU @kfo_5002 at @yourUMG!
Thanks to @DAAD_Germany for making this possible.
Laura Urbach retweeted
Presented some of my PhD work on HDAC inhibition in #PDAC today at #AACRPAN23 - thanks for the opportunity @AACR and the interesting discussions!
The work was conducted in the lab of @ShivKSingh6 at @yourUMG
Happy day! 🥳
@LukasKlein01 and I both received a DAAD international travel grant to attend the AACR Conference on Pancreatic Cancer in Boston next week!
We are very grateful and are looking forward to present our data!👩🏼🔬🧫🔬
#pancreaticcancer #networking
@DAAD_Germany @AACR
Laura Urbach retweeted
Laura @UrbachLaura & I wrote a research highlight @sigtrans_sttt on a fascinating study recently published in @Nature. This study shows how an incorrect splicing event can accelerate #pancreaticcancer metastasis
rdcu.be/dmbah #open access
@Krebshilfe_Bonn @yourUMG
Nature research paper: RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer go.nature.com/42yKSy3




































