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AI-driven discovery for drugs and materials, combining computational models with large-scale automated experimentation.

Cambridge, MA
Joined April 2016
Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)Photo by XtalPi (@XtalPi)
Dr. Lipeng Lai joins us at The Lantern Summit. Co-founder & Chief Innovation Officer of @XtalPi (2228.HK). Now co-founding INFevo, an AI virtual cell built on biological foundation models. Shanghai · 26–27 Oct 2026 thelanternsummit.com 🏮
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Alan Jiang joins us at The Lantern Summit. Chief Strategy Officer at @XtalPi (2228.HK), where AI, quantum physics and robotic labs meet drug R&D. Twenty years at Genzyme and Sanofi before that. Shanghai · 26–27 Oct 2026 thelanternsummit.com 🏮
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XtalPi retweeted
Moderna and @Merck today announced positive topline results from the Phase 3 INTerpath-001 trial evaluating adjuvant treatment with intismeran autogene, a novel investigational mRNA-based individualized neoantigen therapy jointly developed by Merck and Moderna, in combination with KEYTRUDA® (pembrolizumab), Merck's anti-PD-1 therapy, in patients with completely resected Stage IIB-IV melanoma. Read more:
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Happy Earth Day 2023 to all life on planet Earth. A reminder that the first Earth Day was created in 1970, while we were going to the Moon. And when we arrived, we looked back over our shoulders, and discovered Earth for the first time.
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NEW in @RSCAdvances ⭐ Selecting a stable solid form of remdesivir using microcrystal electron diffraction and crystal structure prediction by Sivakumar Sekharan at @XtalPi et al. 🤩 Read it in full 👉 ow.ly/gBdj50EKQNY #OpenAccess #Chemistry
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The round was led by @BGFinvestments, with new investors @xtalpi, @AstellasEurope, @o2hventures & Trend Investment Group. Founding investors Jonathan Milner, @ParkwalkAdvisor & Morningside Ventures also contributed. 2/2
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Replying to @AAPSComms
@AAPSComms has started short weekly talks on the #COVID19 pandemic. The first on April 15th by @XtalPi is on how to use #AI and #computationalchemistry to understand the mechanism of infection and derive treatments. Free to join. Please sign up aaps.org/aaps/education-and-…
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‘Innovation’ nation. China is finally embracing biopharmaceutical innovation, but it is innovation that looks different from that in the West go.nature.com/2Jxl9PM #longform
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XtalPi retweeted
We are glad to have contributed to this piece - a closer look at the burgeoning life science sector in China, and its new generation of innovative pharmaceutical companies and scientists that increasingly work with and contribute to the global drug R&D industry.
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After a densely packed day of @XtalPi #RSFD19 symposium. Specially* crafted cocktails at reception are real treat! * only certain types of nerds will appreciate #RealTimeChem
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“Is Greater China leading the way in #digitalhealth?” - g4a.health/blog/greater-chin… Finally got around to putting some final touches from earlier in the year trip! Curious on other people’s thoughts and views on #china & #digitalhealth cc: @zajctjasa – at Berlin, Germany
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In the #cancer track, congratulations to REC Enroll, Forget Me Not, sneasy Swab and SUCA, the winners of the 1st, 2nd and third place prizes as well as the winner of the @Optum award. #GrandHack2019 @mithackmed @MIT #innovation #medicine
Thank to our global and community sponsors who supported @MIT @mithackmed #Grandhack2019 through in-kind contributions, prizes or media sponsorship: @Figure1 @Optum @AmerAcadPainMed @KochInstitute @MITSandbox @MIT_Innovation @FoleyHoag @xtalPi @MITlinQ @AbelsonTaylor @1up_health
XtalPi retweeted
9. Virginia Burger @XtalPi on small molecule crystal structure predictions #macc #nyagim #compchem
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Google, Tencent, Sequoia China join $15 million funding for pharma startup XtalPi reut.rs/2DwDyac
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A drug’s structure can significantly affect its potential safety, stability and efficacy, and XtalPi’s AI models can also help researchers predict other important characteristics for hit identification and lead optimization: ow.ly/qMki30hZDF1
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CONGRATS to #CACSC #startup finalists & the winning team @XtalPi (#USA)! #CompCon2016 #CloudComputing @InteractiveMob @vibronix @igloohomeco
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XtalPi retweeted
The rise in the requests for orphan drug designation holds promise for the future of rare disease drug development. go.usa.gov/xaq5F
Big Pharma eyes Bay Area, Boston expansions as it cuts R&D elsewhere: Drug… goo.gl/fb/aLTWxl BiotechSF blog
How #openinnovation is improving drug development, by @neilsavagewrite. bit.ly/23BgJrj
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