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YaleMicroPath

@YaleMicroPath

Department of Microbial Pathogenesis, Yale School of Medicine @YaleMed #microbiology #postdoc #PhDstudent #YaleBBS

 New Haven, CT
medicine.yale.edu/micropath/
Joined January 2019
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  • Following72
  • Followers666
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Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)Photo by YaleMicroPath (@YaleMicroPath)
YaleMicroPath retweeted
microbelab (@microbelab) profile picture
microbelab@microbelabOct 27
Mg2+, ATP, and the Control of Bacterial Metabolism - go.shr.lc/3VYkNd9 @AnnualReviews @npokorzynski @microbelab @YaleMed #bacteria #metabolism #microbiology
Mg2+, ATP, and the Control of Bacterial Metabolism

Mg2+, ATP, and the Control of Bacterial Metabolism

In all living cells, chemical reactions known as metabolism generate energy and building blocks for cellular structures. Metabolism produces and consumes ATP, the major currency of cellular energy....

annualreviews.org
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLabSep 1
nature.com/articles/s41467-0… @guowangbiao @YueJianUSTC @cryoHuaxinYu @YaleMicroPath @YaleMed #insitu #cryoEM #Vibriocholerae #flagella #motility
Near-atomic in situ architecture and membrane-coupled dynamics of the Vibrio cholerae sheathed...

Near-atomic in situ architecture and membrane-coupled dynamics of the Vibrio cholerae sheathed...

Nature Communications - The sheathed flagellum of the pathogen Vibrio cholerae supports bacterial motility, environmental survival, and persistent colonization of the human gut. Here, the authors...

nature.com
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLabJun 25
nature.com/articles/s41467-0… @guowangbiao Jiaqi Clem Wang Jack Botting @YaleMicroPath @YaleMed et al #cryoET #cryoEM #spirochetes
Asymmetric architecture and adaptation of Treponema flagella

Asymmetric architecture and adaptation of Treponema flagella

Nature Communications - Here, the authors present cryo-EM structures of the intact asymmetric core–sheath supercoiled flagellar filament in Treponema denticola, a major periodontal pathogen,...

nature.com
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YaleMicroPath retweeted
microbelab (@microbelab) profile picture
microbelab@microbelabJun 22
Excellent work @embojournal from former @microbelab @YaleMed Groisman Lab members Emilia Krypotou, Guy Townsend, et al link.springer.com/article/10… #Btheta #Rho #phaseseparation
Short autoinhibitory sequences control phase separation of an essential bacterial transcription...

Short autoinhibitory sequences control phase separation of an essential bacterial transcription...

The EMBO Journal - Within cells, across diverse organisms, macromolecular condensation enables spatial and temporal organization of biochemical reactions by organizing proteins and nucleic acids...

link.springer.com
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLabMay 16
Congratulations to @JunLiuLab @YaleMicroPath researcher @guowangbiao for receiving the poster award at the 11th Annual @Yale Biophysics and Structural Biology Symposium!
Image from Jun Liu Lab (@JunLiuLab)
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Congratulations to the Mougous Lab, recent arrivals at Yale’s Microbial Sciences Institute @YaleMicroPath, on their discovery of “umbrella toxins” cell.com/cell/fulltext/S0092… @CellPressNews @YaleMed
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab3 Dec 2025
#preprint from @JunLiuLab #postdoc @guowangbiao and @YueJianUSTC @YaleMed #Vibriocholerae #flagellum biorxiv.org/content/10.64898…
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab17 Nov 2025
Congratulations to #postdoc @cryoHuaxinYu @JunLiuLab @YaleMed for insightful findings @ScienceAdvances #cryoEM #cryoET #Lambdaphage Structural basis of bacteriophage Ur-lambda infection initiation science.org/doi/10.1126/scia…
Structural basis of bacteriophage Ur-lambda infection initiation

Structural basis of bacteriophage Ur-lambda infection initiation

In situ structures reveal molecular insights into infection initiation of bacteriophage Ur-lambda.

science.org
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab31 Oct 2025
Beautiful work using #insitu #cryoEM #SingleParticleAnalysis from @guowangbiao @YaleMicroPath in @NatureMicrobiol nature.com/articles/s41564-0…
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Now in 3D: Yale scientists catch Legionnaires' disease ‘in the act’. bit.ly/nowin3D @Yale @PNASNews @JunLiuLab @YaleMicroPath @Goodman_lab
Now in 3D: Yale scientists catch Legionnaires' disease ‘in the act’

Now in 3D: Yale scientists catch Legionnaires' disease ‘in the act’

The Yale labs of Craig Roy and Jun Liu have harnessed the power of cryo-EM to solve a 30-year mystery of how the Legionella bacteria works

westcampus.yale.edu
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab23 Sep 2025
Great work from @YueJianUSTC @YaleMicroPath @YaleMed in @PNASNews #Legionella #T4SS pnas.org/doi/10.1073/pnas.25…
In situ structures of the Legionella Dot/Icm T4SS identify the DotA–IcmX complex as the gatekeeper...

In situ structures of the Legionella Dot/Icm T4SS identify the DotA–IcmX complex as the gatekeeper...

The Dot/Icm machine of Legionella pneumophila is among the most versatile type IV secretion systems (T4SSs), capable of translocating more than 330...

pnas.org
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YaleMicroPath retweeted
microbelab (@microbelab) profile picture
microbelab@microbelab29 Aug 2025
We @microbelab are so thankful as we congratulate former lab member and outstanding scientist @npokorzynski on his appointment as Assistant Professor of Microbiology @OregonState #MetabolicReprogramming #proteolysis #antibioticsusceptibility microbiology.oregonstate.edu…

Nick Pokorzynski | Department of Microbiology

microbiology.oregonstate.edu
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YaleMicroPath retweeted
Andy Goodman (@Goodman_lab) profile picture
Andy Goodman@Goodman_lab16 Jul 2025
New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @Aman_Kr25 @RobynTamblyn and the rest of the team. nature.com/articles/s41586-0…
Image from Andy Goodman (@Goodman_lab)
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab11 Jul 2025
Happy to share @JunLiuLab @YaleMed #postdoc Samira Heydari’s chapter on #cryoET @ElsevierConnect shop.elsevier.com/books/cryo…
Cryo-electron Tomography

Cryo-electron Tomography

Cryo-Electron Tomography: A Journey from Sample Preparation to Data Mining providing a holistic overview of this rapidly advancing field and equipping researchers with the knowledge and tools...

shop.elsevier.com
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YaleMicroPath retweeted
microbelab (@microbelab) profile picture
microbelab@microbelab11 Jul 2025
New #postdoc applications welcome to continue excellent research investigating stress responses and virulence in #Salmonella. #biochemistry #molecularbiology medicine.yale.edu/lab/groism…
Join the lab!

Join the lab!

We welcome applications for postdoctoral positions in the Groisman Lab in the Department of Microbial Pathogenesis at Yale School of Medicine to investigate

medicine.yale.edu
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab30 Jun 2025
Exciting findings from @JunLiuLab #postdoc @YueJianUSTC @YaleMed Architecture and activation of the Legionella Dot/Icm type IVB secretion machine #cryoEM #cryoET #Legionella biorxiv.org/content/10.1101/…
In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper...

In-situ structures of the Legionella Dot/Icm T4SS identify the DotA-IcmX complex as the gatekeeper...

The Dot/Icm machine in Legionella pneumophila is one of the most versatile type IV secretion systems (T4SSs), with a remarkable capacity to translocate over 330 different effector proteins across the...

biorxiv.org
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab21 May 2025
Congratulations to #postdoc Jiaqi Guo @JunLiuLab @YaleMicroPath on her poster prize at the 10th Annual Biophysics and Structural Biology Symposium @YaleChem #cryoET #cryoFIB #cryoEM medicine.yale.edu/profile/ji…
Jiaqi Guo

Jiaqi Guo

My research focuses on how nanoscale structures drive bacterial motility and interact with host cells. In Vibrio cholerae, the pathogen that causes cholera, a

medicine.yale.edu
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YaleMicroPath retweeted
Jun Liu Lab (@JunLiuLab) profile picture
Jun Liu Lab@JunLiuLab19 May 2025
Congratulations to our #postdoc Shoichi Tachiyama @JunLiuLab on his paper @mbiojournal journals.asm.org/doi/10.1128… #T6SS #cryoET
Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and...

Outer membrane tube formation by Francisella novicida involves extensive envelope modifications and...

Francisella tularensis is an intracellular bacterial pathogen that causes the zoonotic disease tularemia. Following uptake by host cells, the bacteria rapidly escape the phagosome and replicate...

journals.asm.org
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YaleMicroPath retweeted
microbelab (@microbelab) profile picture
microbelab@microbelab16 Apr 2025
news.yale.edu/2025/04/14/inf… #Salmonella @npokorzynski @YaleMed

Infection control: How a pathogen survives a hostile environment

A new Yale study reveals the molecular process that helps pathogens thrive in hostile environments — and may offer important insights into antibiotic resistance.

news.yale.edu
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Scientists at the Yale Microbial Sciences Institute reveal a strategy used by microbes to stay ahead in the ‘molecular arms race’ taking place in our gut bit.ly/gut-wars @Goodman_lab @YaleMed @cellhostmicrobe @YaleMicroPath @Yale
Image from Yale West Campus (@YaleWestCampus)
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