Dr. Yan Liu’s laboratory at the Northwestern University is interested in investigating hematopoietic stem cells and Hematologic malignancies, CHIP, MDS, AML
Chicago, IL
Joined July 2019
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I was promoted to full professor with tenure at Northwestern University Feinberg School of Medicine today. I like to thank my mentors, trainees, colleagues, friends and my family for their continued support!
Yan Liu Lab Northwestern retweeted
Excited to share our new study published online today @CD_AACR. Beyond mutagenesis, we show that LINE-1 locus-specific transcription reshapes 3D genome architecture to control cancer gene expression @JianXuLab @StJudeResearch
aacrjournals.org/cancerdisco…
My lab together with @AbdelWahablab published a paper recently in JCI reporting that mutant p53 drives clonal hematopoiesis through generating a chronic inflammatory micro environment. Our work suggests that curbing inflammation may prevent the progression of CHIP to leukemia.
The Liu lab was established on November 1, 2010. 2025 marks the 15th anniversary of the Liu lab. I like to take this opportunity to thank my mentors, trainees, collaborators, friends and family for their support over the years! Looking forward to the next 15th anniversary!
Celebrating a MPI (Liu/Yue/ Sukhanova) R01 from NCI, which started in December 10. It is a great collaboration between @YanLiu_Lab ,@yuefeng_1 , and @MadinaSukhanova at Northwestern University @NUFeinbergMed and @LurieCancer ! We are looking forward to continued collaboration. – at Chicago, IL
Congratulations to my mentor @DrSDNimer , who received the Mentor Award from @ASH_hematology 🎉📝🎉🍾🎊🎉today!
It is great to meet my postdoctoral mentor, @DrSDNimer, at Northwestern University. He gave a wonderful keynote speech at @LurieCancer symposium today on histone modify enzymes in hematological malignancy. He is instrumental in guiding me through a research career in Hematology!
Yan Liu Lab Northwestern retweeted
It is with heavy hearts that we announce the passing of our beloved colleague and friend, C. David Allis. Aside from his groundbreaking contributions to biomedical science, David will be remembered for his warmth, humility, and relentless optimism.
Yan Liu Lab Northwestern retweeted
Spotted…Dr Nimer (@DrSDNimer ) reciting M’s Lose Yourself at the Miami nights amazing 🎈 party!!! #ASH22 @UMiamiHealth
Yan Liu Lab Northwestern retweeted
Great to meet old and new friends at the MIAMI night #ASH22 @yuefeng_1 @PengJi_lab, Yali Dou, Gang Huang @YanLiu_Lab
Congratulations to my PhD student @SergioB26346510 for receiving the ASH minority Abstract Achievement Award! I am so proud of his achievement!
Yan Liu Lab Northwestern retweeted
We have an opening for a post-doctoral fellow in my lab to work on mechanisms of cytokine signaling in brain tumors and pancreatic cancer.
If interested, please send your CV & cover letter to my attention at this email address: [email protected]
Yan Liu Lab Northwestern retweeted
Patients with acute myeloid #leukemia show large-scale #genomic mutations and altered DNA folding patterns that could help identify potential therapeutic targets, according to a study in @Nature from @yuefeng_1 @LurieCancer news.feinberg.northwestern.e… via @NUFeinbergMed #leusm #AML – at Chicago, IL
My outstanding PhD student @SergioB26346510 has won the ASH Minority Graduate Student Abstract Achievement Award for his presentation at the 2022 ASH meeting! I am so happy for his achievement! He will be a great postdoc fellow to have in a hematology lab! – at Chicago, IL
Yan Liu Lab Northwestern retweeted
Announcing again a unique workshop on Lineage Plasticity & Cell-of-Origin of Hematologic Malignancies this Friday October 14, 2022. Hosted by @CHM_MSKCC & @MSKPathology @MSKCancer Center. Registration and updated final agenda below:
meetmsk.zoom.us/meeting/regi…
Here is the link to our Blood paper showing PRL2 dephosphorylates CBL at tyrosine 371 to enhance FLT3 signaling in leukemia cells. Our work also established PRL2 as a novel therapeutic target in AML.
ashpublications.org/blood/ar… – at Chicago, IL
Excited to announce our recent work on PRL2 and oncogenic FLT3 signaling in AML published in Blood! Lead by Hongxia Chen and Yunpeng Bai. Thank my long term collaborator Dr. Zhong-Yin Zhang at the Purdue University and other collaborators at IUSM and Northwestern! – at Chicago, IL
