@Yin_Lab_FSU
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Structural immunologist @floridastate @FSUbio @FSUcmb, interested in the membranes as the intersection of inflammation and cellular homeostasis
Tallahassee, Florida
Joined December 2020
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Yin Lab retweeted
Most researchers collect data first, then wonder why nobody reads their papers.
Start with the story.
The data comes after.
Yin Lab retweeted
♻️ Please share, friends and colleagues!
📢 Hiring postdocs for my lab @UCBerkeley. Let’s make discoveries as iconic as the Campanile!
👉 Apply: bit.ly/ShiyuXiaLab
Seeking:
🧪 Biochemists
🧬 Structural Biologists
🛠️ Synthetic Biologists
🐭 Animal Model Experts
#Biochemistry #StructuralBiology #SyntheticBiology #AnimalModel #PostdocJobs
Our structural and functional studies on AAGAB pseudoGTPase domain is online @Structure_CP now! AAGAB pseudoGTPase domain protects adaptor complex sigma subunits through a unique interface distinct from small GTPases.
cell.com/structure/fulltext/…
It was a great collaboration with Shen Lab @CUBoulderMCDB. Our own @fsubio colleagues Drs. Bing Wang and Yuan Tian and @FSUcmb doctoral student Rui Yang led the structural and biochemical work.
Yin Lab retweeted
Recognizing the women scientists who laid the groundwork for recent #AI @NobelPrize in Chemistry and Physics
—Helen Berman, who started the Protein Data Bank, used for #AlphaFold (@demishassabis and John Jumper)
nature.com/articles/d41586-0…
—@drfeifei who built ImageNet, foundation for the deep learning revolution (@geoffreyhinton)
wired.com/story/plaintext-fe…
Our protocol on Dengue virus protease cleavage of DNA sensor cGAS is out as a chapter in Springer Protocols’ Antiviral Innate Immunity book! Check out the work of @Maddy4890 and @Debipreeta_FSU! @mobfsu @FSUcmb
Congratulations Dr. Chen! It is a well deserved recognition of your contributions to and impact on the innate immunity and inflammation fields. Your work has always been source of inspiration.
Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” laskerfoundation.org/winners… #Lasker2024 #LaskerLaureate
The nicest kind of suprise! Pleased to see a Commentary by @guntherwho on our most recent collaborative work on CCDC32.
pnas.org/doi/10.1073/pnas.24…
Stepwise assembly of the AP2 endocytic clathrin adaptor complex | PNAS pnas.org/doi/10.1073/pnas.24…
Wow
Thrilled to announce AlphaFold 3 which can predict the structures and interactions of nearly all of life’s molecules with state-of-the-art accuracy including proteins, DNA and RNA. Biology is a complex dynamical system so modeling interactions is crucial blog.google/technology/ai/go…
Congratulations! Such a cool structure!
Exited to share our new paper by Gang Du @ , Liam @L_Heals, Liron David @LironDavid2 and others on GSDMD palmitoylation. “ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D” in Nature nature.com/articles/s41586-0…. Even full-length GSDMD can form pores!
On my reading list!
Comprehensive review and extremely beautiful graphics on innate immune mechanisms!
By @jf033 @inflammasomelab @WuLabHarvard
Congratulations Dr. Maddy and Dr. Roy! @Maddy4890 @Sayantan3690
We are late to congratulate the newly minted @mobfsu graduate, Dr. Bhattacharya, from the @Yin_Lab_FSU. Can we also take credit for Dr. Roy, also from @Yin_Lab_FSU but a graduate of @FSUcmb.
Congratulations to Hao @WuLabHarvard and all winners!
Please join us in congratulating the winners of the ASBMB annual awards! Colleagues nominated the winners for making significant contributions to biochemistry & molecular biology & training emerging scientists. Recipients will give talks at #DiscoverBMB! asbmb.org/asbmb-today/people…
It’s such a pleasure to work with the talented and hardworking @Debipreeta_FSU in the past few years. Best wishes for all your future endeavors!
Bidding farewell to our beloved @Debipreeta_FSU!! We will remember you as an extremely talented and a hardworking person. Wish you all the best for your future.
Yin Lab retweeted
The #ShawPrize in #LifeScienceAndMedicine 2023 is awarded in equal shares to Patrick Cramer and Eva Nogales for pioneering structural biology that enabled visualization, at the level of individual atoms, of the protein machines responsible for #genetranscription.
#ShawPrize2023
Yin Lab retweeted
Giving good talks is a core skill for academics. It's learnable!
Here's how I approach mine.
drive.google.com/file/d/1SHi…
Our work on DENV protease cleaves and deactivates cGAS is now on @jbiolchem! The factor that an RNA virus antagonizes the DNA sensor speaks volumes of the complexity of host-virus interactions!
jbc.org/article/S0021-9258(2…
The work is led by @mobfsu doctoral student Madhurima Bhattacharya @Maddy4890 and @fsubio postdoctoral scholar Debipreeta Bhowmik @Debipreeta_FSU. Congratulations!
Yin Lab retweeted
New review article on STING trafficking to start 2023!
We discuss how STING trafficking influences signaling, propose a model of tonic STING signaling, and discuss an emerging link between dysregulated STING trafficking and neurodegenerative disease.
rupress.org/jem/article/220/…
