The CSVCC is a convergent approach to cancer research that combines advances from diverse scientific disciplines to improve outcomes for patients.
Joined June 2021
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Convergent Science Virtual Cancer Center retweeted
New research from @DanaFarber’s @SarahJHill6 reveals that as CDK4/6 inhibitors are being investigated as a possible treatment in endometrial cancer, RB function-predictive transcriptional signatures may be a relevant biomarker to help predict response to therapy.
➡️bit.ly/4wBUR4b
Convergent Science Virtual Cancer Center retweeted
Dr. Dan Theodorescu, director of the @UAZCancer, has been awarded the prestigious Spence Medal by the American Association of Genitourinary Surgeons, honoring his lifetime of discoveries in cancer research and precision medicine. Congratulations! More: tinyurl.com/85mfyps7
ALT Portrait of Dr. Dan Theodorescu, director of the University of Arizona Comprehensive Cancer Center
Convergent Science Virtual Cancer Center retweeted
Excited to be at the @_CSVCC retreat, inspiring start honoring Adam Hayden - his memory will live on and inspire us to continue to innovate in #CancerResearch
Convergent Science Virtual Cancer Center retweeted
A @UAZCancer researcher received a $1.7M grant to continue the Convergent Science Virtual Cancer Center, with the University of Southern California, training researchers to address cancer risks in military communities. More: tinyurl.com/4nsxvp9r
ALT An image of confocal cancer cells and fibroblasts in collagen
Convergent Science Virtual Cancer Center retweeted
Our work on Macrophages and Breast cancer brain metastasis is finally out @PNASNews doi.org/10.1073/pnas.2420793… Thanks editors，reviewers, and all authors.
Convergent Science Virtual Cancer Center retweeted
I am looking forward to presenting a short talk on our work on macrophage ontogeny at the @ISEHSociety annual meeting.
Convergent Science Virtual Cancer Center retweeted
A great collaboration with my friend @JunQiLab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.
Proof-of-concept: Epigenetic reprogramming could one day be a new therapeutic path in colorectal cancer. @Nilay_Sethi explains how histone acetylation shapes CRC cell fate in this @AGA_Gastro study: bit.ly/46gS7z1
Convergent Science Virtual Cancer Center retweeted
Disrupting cell communication in glioblastoma—
@PeiwenChen9 and team @ClevelandClinic discover GPNMB mediates bidirectional communication between GBM stem cells and tumor-associated macrophages and microglia: insight.jci.org/articles/vie…
Convergent Science Virtual Cancer Center retweeted
Improving immunotherapy in glioblastoma!
@PeiwenChen9 & team @ClevelandClinic discover targeting legumain—which promotes infiltration of tumor-associated macrophages via the GSK3β/STAT3 pathway—has anti-tumor effects and improves immunotherapy in preclinical GBM models: jci.org/articles/view/186034
Convergent Science Virtual Cancer Center retweeted
Happy to share our work out at @jclinicalinvest We identified a new tumor-macrophage interaction contributing to GBM progression/immunosuppression and found that targeting the symbiosis sensitizes GBM to immunotherapy. Huge thanks to editors and reviewers. jci.org/articles/view/186034
Convergent Science Virtual Cancer Center retweeted
Here's a new preprint from our group. This manuscript continues our efforts to understand the mechanisms that distinguish fetal/juvenile versus adult hematopoiesis to better understand pediatric blood diseases.
biorxiv.org/content/10.1101/…
Convergent Science Virtual Cancer Center retweeted
New research finds that a ketogenic diet enhances CAR T Cell antitumor function via β-Hydroxybutyrate ft. @Shan_Liu_, @MaayanLevy_Lab (@PennMicro), @PuneethGuru_ (@PennMedicine), @MarcoRuella & Elise Chong (@PennCancer) tinyurl.com/4tw6eddy
Convergent Science Virtual Cancer Center retweeted
Just in time for #ASH24, our latest is online:
nature.com/articles/s41592-0…
Convergent Science Virtual Cancer Center retweeted
Excited to share our review: “Immunotherapy for GBM: current state, challenges, and future perspectives ", just published in @Cellular & Molecular Immunology rdcu.be/dW19V
Convergent Science Virtual Cancer Center retweeted
Excited to share our paper just accepted by @jclinicalinvest. We reveal a new macrophage-microglia interplay in GBM and develop a powerful therapeutic approach targeting them.
jci.org/articles/view/178628
Convergent Science Virtual Cancer Center retweeted
Here is our latest paper now online @LeukemiaJnl.
nature.com/articles/s41375-0…
Convergent Science Virtual Cancer Center retweeted
Thanks @CR_AACR for this opportunity to write the commentary highlighting a fantastic paper from @CellCellPress “Macrophage-mediated myelin recycling fuels brain cancer malignancy” by Dr. Leila Akkari and colleagues.
aacrjournals.org/cancerres/a…
Convergent Science Virtual Cancer Center retweeted
Enjoyed participating in this fantastic session chaired by @AleksSkardal Shay Soker and Damian Hutchins at #TERMIS2024 @TERMISAM
Convergent Science Virtual Cancer Center retweeted
Thank you @jclinicalinvest for this opportunity to write this review focusing on epigenetic regulation of tumor immunity.
Convergent Science Virtual Cancer Center retweeted
A research team led by @Dan_Theodorescu, the director of @CedarsSinai Cancer in Los Angeles, is using AI to isolate more effective biomarkers than the CA 19-9 test to track & predict pancreatic cancer progression. h/t @letswinpc #pancsm. letswinpc.org/research/ai-fi…