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Excited to share our work on mechanisms of oxygen toxicity! As a @UCSFCardiology fellow, I wondered why excess supplemental oxygen is associated with adverse outcomes. Here we take a deep dive into O2 toxicity. bitly.ws/BjZW @UCSF @GladstoneInst @ishahjain
Alan Baik retweeted
I am excited to share our latest preprint, in which we demonstrate that systemic hypoxia suppresses solid tumor growth.
This has been a tremendous collaborative effort in the labs of @IshaHJain and @Genophoria at @GladstoneInst, @ArcInstitute, and @UCSF.
biorxiv.org/content/10.64898…
The Baik Lab at UCSF (CVRI) is hiring a post-doc! We study hypoxia adaptation in cardiovascular disease and mechanisms of cancer therapy-related cardiotoxicities. Collaborative culture, strong mentorship, and innovative approaches! Email CV + cover letter to [email protected]
Alan Baik retweeted
Proud to announce the creation of the UCSF Pericarditis Center led by @baik_alan! Great addition to @UCSFCardiology Section of #CardioOnc & Immunology! Website made by @UCSFDOM PGY2 resident extraordinaire @aishwarya_nene! @Bob_Wachter @MandarArasMD
ucsfhealthcardiology.ucsf.ed…
Incredibly grateful for the support. Many thanks to my mentors (past and current @ishahjain @CardioOncology @kaelin_lab, many others) and @UCSFCardiology @UCSF
Announcing the Recipients of the 2024 Career Awards For Medical Scientists bwfund.org/news/announcing-t… #bwfcams
Alan Baik retweeted
Check out our case of acute radiation-induced pericarditis complicated by polymicrobial infectious pericarditis in a patient with mediastinal sarcoma: academic.oup.com/ehjcr/artic…
Mentored by the amazing @baik_alan #CardioOnc #UCSFCardiology
Alan Baik retweeted
Our new paper: rb.gy/w1kvk0! @kirsten_chenx et al. looking at in vivo protein turnover vs O2. We confirm our previous work that C1 stability is O2-sensitive and nominate MYBBP1A as a mediator of the hyperoxia response (HIF for hyperoxia?)
News: rb.gy/ammgdu
Happening now at #AHA23 - the promise and perils of the omics revolution in cardio-oncology. Great talk by Jose Fuster on CHIP mutations and increased risk of CVD @AartiAsnaniMD @SvatiShah @AHAScience
Thanks to a supportive department and division, as well as incredible mentors especially @CardioOncology @ishahjain @Jeffolgin and many others
Big congrats to Section of #CardioOnc & Immunology faculty member @baik_alan in being promoted to Assistant Professor of Medicine at @UCSF! Alan's research revolves around manipulating hypoxia in #CardioOnc including w/ HIF2 inhibitors (e.g., belzutifan)! @UCSFCardiology
Alan Baik retweeted
Big congrats to Section of #CardioOnc & Immunology faculty member @baik_alan in being promoted to Assistant Professor of Medicine at @UCSF! Alan's research revolves around manipulating hypoxia in #CardioOnc including w/ HIF2 inhibitors (e.g., belzutifan)! @UCSFCardiology
We are hiring a research assistant! Join me in the @ishahjain lab to study oxygen metabolism in cardiovascular disease. See tinyurl.com/ms2ncvmm for job posting or send me a DM to learn more!! @UCSFCardiology @GladstoneInst @UCBerkeley @UCLA @UCSF @StanfordBiosci
Alan Baik retweeted
Yesterday I shared @ishahjain's work on *low* oxygen. Today, she, @baik_alan & @kirsten_chenx have a paper in @MolecularCell on why *high* oxygen is harmful. Her @GladstoneInst @UCSF team discovered that too much O2 "rusts" proteins w/ sulfur & oxygen.
gladstone.org/news/researche…
Hyperoxic injury to the ETC results in higher levels of unused oxygen, further exacerbating cellular and tissue toxicity. Important implications for mitochondrial disease, oxidative stress, aging, I/R injury!
Alan Baik retweeted
For anyone interested in #CardioOnc & #CardioImmunology, I highly recommend coming 2 this session #AHA22 on Saturday! A+ speakers & especially talk by @DrJESalem! It will provide a new paradigm for treating myocarditis patients! Game changer in the field! @UCSFCardiology
Alan Baik retweeted
Nice piece highlighting Dr. Alan Baik @baik_alan in our section! Alan is already a star in #CardioOnc & #Hypoxia research! Had the pleasure to work with Alan for much of ht last 10 years! @MandarArasMD @drycm2d @AmirZMunir @JayaMallidi
ucsfhealthcardiology.ucsf.ed…
Alan Baik retweeted
We are back! The @UCSF Section of #CardioOnc & immunology conferences! Excited to have @baik_alan present on the CV tox of VEGF inhibitors. Now about a dozen of these drugs. Biologically interesting b/c of similarity 2 pregnancy-associated CV issues! #CardioObstetrics #PPCM
Dream team!
Introducing new members of the @UCSF Section of #CardioOnc & Immunology. Grateful 2 both Eileen Gutierrez & Amanda Schnell-Heringer for providing A+ care for our patients. Super excited for the care we provide for our patients at @UCSFCancer! @MandarArasMD @JayaMallidi @baik_alan
Alan Baik retweeted
Nice @kaelin_lab #CardioOnc team reunion at #42Annual @SarnoffCardio meeting. We brought heart to Mayer4! #BenOlenchock @QingZhangLab @CellDeathLab @AChakrabortyPhD @sagarkoduri2 @DrChoueiri @AdamsBioAging – at San Francisco, CA














