programming biology
California, USA
Joined April 2017
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there are many use cases for the genome, and growing!
here are 5:
- finding disease variants
- predicting drug metabolism
- mapping pathways
- prioritizing targets
- detecting integrated viral DNA
way more here: bradleywoolf.com/links-2/wha…
very true words from @BenLamm when he was building Chaotic Moon
angelinvestinginaustin.blogs…
synbio/programmable biology was the original reason for me programming computers
last year i sought to understand how it could be usable to an average person, and generative, on-demand medicine is possible
so i made bee antivenom, since i am allergic
bradleywoolf.com/de-novo-ant…
I'm excited to share something I've been working on...
NeoGenesis Capital is a new fund focused on the intersection of superintelligence and synthetic biology.
I believe some of the most extraordinary breakthroughs of the coming decade will happen at this intersection.
I'll be sharing more on @moonshots_pod soon, including why I'm so excited about what's ahead!
What is interesting is that you can still plug the chip into the base of the MinION, even after separating everything
In summary:
- everything screws together (except the chip itself, which appears to be manufactured as one unit)
- You use it 1-3x then throw it away, like the SpaceX rocket analogy of throwing away a rocket every time you fly
- DNA + some fluid flows through the nanopores and is discarded on the side
- Nanopore sensing can be used for RNA, proteins, peptides, and other molecules
- an electrical current is applied across the pore array, and when DNA bases pull them through, an algorithm reads that
“the golden age of biology, like physics in the 30s”
youtu.be/ctWqrWAd1vw?is=cvm6…
my thoughts on the $0 genome :
why aren't DNA sequencing companies offering WGS for $0?
if we consider the $300 WGS cost as CAC, then all that is left is to make LTV > CAC
but what is the value? a data structure like Google? commerce like Amazon?
bradleywoolf.com/links-2/the…
