Have you read an outstanding paper published in Brain Communications during 2025? Take note of it for the Early Career Researcher Paper Prize! Nominations are Open! #ecr #paperprize #neuroscience Link to form: buff.ly/8DWT8TV Find out more at: buff.ly/5WfBuCR

Meier et al. found that increase in white matter volume, diffusivity and inositol, and abnormal magnetization transfer indicate pre-symptomatic white and grey matter involvement in asymptomatic adolescent adrenoleukodystrophy patients. Read it at 👉buff.ly/TbzGb2P

Kapadia et al. highlight that the study by Bechkos et al. (2026) independently corroborate previous evidence that electrical stimulation reduces α-synuclein oligomerisation in Parkinson’s disease models. Read it at 👉buff.ly/c3RWM5j #neuroscience #braincommunications

Meet Alfred Kongnyu Njamnshi, a Professor of Neurology and Neuroscience at the University of Yaoundé I and the founder of Brain Research Africa Initiative (BRAIN)👋 He researchers sleep and neurocognitive disorders associated with parasitic infections, HIV and stroke.

Zoellin et al. show that autologous haematopoietic stem cell transplantation is associated with reduced retinal tissue loss in relapsing-remitting multiple sclerosis, with baseline inner nuclear layer thickness predicting better outcomes. Read it at 👉buff.ly/qTHPDO4

Pini et al. review developmental biomarker changes, proposing that increased p-tau217 and glial fibrillary acidic protein in Alzheimer'’s disease may reflect unresolved adaptive brain programmes rather than toxic responses. Read it at 👉buff.ly/epphj5D #neuroscience

Leveraro et al. report that patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder show altered functional brain organization despite preserved cognition. Read it at 👉buff.ly/BOaMba0 #neuroscience #braincommunications

Conti et al. report that impaired awareness of visual hallucinations in Lewy body disease involves reduced resting-state connectivity between right visual association and prediction-error systems. Read it at 👉buff.ly/ItuMXvA #neuroscience #braincommunications

Xiong et al. report that a deep learning model using susceptibility-weighted MRI of the substantia nigra and adjacent structures predicts motor outcome after subthalamic nucleus deep brain stimulation in Parkinson’s disease. Read it at 👉buff.ly/oLYnHD2 #neuroscience

Norouzi et al. studied periodic and aperiodic resting-state features in Parkinson’s patients across six EEG and MEG datasets, finding elevated alpha power, slower alpha peak frequency, and higher aperiodic offset and exponent. Read it at 👉buff.ly/ouVad3F #neuroscience

Keute et al. report that verbal and visuospatial working memory outcomes after deep brain stimulation in Parkinson’s disease were linked to baseline cortical activity and stimulation-related spectral changes. Read it at 👉buff.ly/IVZQIgn #neuroscience

Braun et al. report that human synucleinopathy is associated with astroglial water channel aquaporin-4 mislocalization and glymphatic clearance of α-synuclein is impaired in a mouse model with loss of perivascular aquaporin-4. Read it at 👉buff.ly/KfcwH7V #neuroscience

Oatman et al. studied how brain gene expression relates to levels of key Alzheimer’s disease proteins: amyloid-β, tau, and APOE. Most changes were related to levels of tau protein. Read it at 👉buff.ly/HmQxdUW #neuroscience

Meron et al. report reduced neural responsivity to startling stimuli in post-ictal larval zebrafish, alongside increased receptor density at inhibitory glycinergic synapses. Disrupting these receptors restores responsivity. Read it at 👉buff.ly/uYmo0Lj #neuroscience

Ringshaw et al. demonstrated that antenatal maternal anaemia may impact child brain structure as early as infancy, with detectable effects from 12 months of age, using ultra-low-field MRI. Read it at 👉buff.ly/sFq2qiG #neuroscience #braincommunications

Goret et al. characterize a Dnm2K562E/SC− mouse model combining a K562E dynamin-2 mutation with Schwann cell-specific deletion, capturing key Charcot–Marie–Tooth features. Dynamin-2 delivery post-onset didn't reverse disease. Read it at 👉buff.ly/VHDOtO5 #neuroscience

Malfer et al. report 69.3% 20-year dementia incidence in a parkinsonism cohort (67.8% in Parkinson’s disease), with risk linked to impaired postural reflexes, orthostatic hypotension, smooth pursuit changes and reduced ocular range of motion. Read it at 👉buff.ly/G7I6xyy

Meet Dr Roisin McMackin, an Assistant Professor of Physiology at Trinity College Dublin 👋 She studies neural network dysfunction in health and neurodegenerative diseases, focusing on amyotrophic lateral sclerosis and Huntington’s disease. #meettheteam #braincommunications

Aldridge et al. report 319 genetic variants associated with multiple stroke recovery domains. Genome-wide analyses across 6 recovery domains in 565 participants further identified variants linked to neural plasticity genes. Read it at 👉buff.ly/NPlsvrA #neuroscience

Laginha et al. report consistently reduced plasma and CSF prion protein (PrP) in D178N carriers, supporting plasma PrP as a promising pharmacodynamic biomarker for PrP-lowering trials for prion diseases. Read it at 👉buff.ly/aiVaEky #neuroscience #braincommunications

Using clinically acquired brain MRI from 442 individuals with focal epilepsy, Ndagijimana et al. demonstrate that hippocampal volumetric asymmetry is a robust marker of pathologically confirmed hippocampal sclerosis. Read it at 👉buff.ly/MBycQLp #neuroscience