Bush Lab (@bushresearch) header
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The Bush Lab is a research group at the University of Washington in Seattle. We advance mass spectrometry for biophysics and structural biology.

Seattle, WA
Joined September 2019
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When did Thermo end support for the LTQ Orbitrap XL? My Google skills are apparently not up to that task. Thanks!
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Update: the 2025 Advancing Mass Spectrometry for Biophysics and Structural Biology conference will be held at Georgia Tech. The most current information will always be available on our website: advancingms.org/
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Day 2. Interesting talk by Lindsay Ulmer of the @bushresearch lab at UW given her take on increasing crosslinked PSMs using targeted DDA without inclusion lists increases the PSM count 8 fold #cascadiaproteomics
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Great lightening talk by PhD candidate Alice Martynova @bushresearch on Unraveling Polarity-Specific ESI Mechanisms for Native Mass Spectrometry and the contribution of salt to neg ion ESI of proteins
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Congratulations to May Constabel, who successfully defended her master's thesis! We all wish May great success with the #MSLaserLab @anoukrijs biophysicalms.org/may-consta…
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New Publication: Quantitatively Differentiating Antibodies Using Charge-State Manipulation, Collisional Activation, and Ion Mobility – Mass Spectrometry. biophysicalms.org/new-public…
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Despite the face melting heat in Austin, kudos to @BrodSquadUT for organizing a successful @AdvancingMass conference. Talks later today by @GarciaLabMS @NLKProteomics and others. Neat proteomics talk now by Khiry Patterson from @RenASRobinson1 group.
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Replying to @GozzoTheresa
@GozzoTheresa from @bushresearch (BTW Bush research has a familiar Aussie ring about it doesn’t it @chrashwood?) tells #cascadiaproteomics how to make IgG1 and IgG4 to fly in ion mobility for biophysical characterization better than native MS. PS sorry for the slight detour 😂
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Replying to @AliceMartynova
@AliceMartynova presenting a lightning talk on native MS to count ligands to FA binding proteins. Another example of multifaceted work from @bushresearch at #cascadiaproteomics
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Nice talk from @lindseyulmer1 from @bushresearch at #cascadiaproteomics on optimized chemical cross linking showing the talent of @UWChemistry students
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Native mass spectrometry studies often report initial pH, but is that the pH of samples during experiments? Using ratiometric fluorescence imaging, we find that sample pH can drift during experiments. #nativeMS doi.org/10.1021/jasms.3c0014…
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Great research by @GadzukShea, Evan Hubbard, and @GozzoTheresa! Feel free to contact [email protected] to request a reprint of the article.
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To what extent and on what timescales do the structures of proteins change in the gas phase? We used time-dependent IM-IM-MS and collision-induced unfolding to find out. Great work from Ben Zercher, Cece Hong, @AddisonRoush, and Bruce Feng! #MassSpec #CIU #IMMS #NativeMassSpec
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Great to catch up with lab alumni @GadzukShea, @dcanzani_, and Evan Hubbard! #asms2023
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MONDAY (5/15): Join us for Lisa Jones #analyticalchemistry seminar, “Protein Footprinting Coupled with Mass Spectrometry: A New Method for In-Cell Structural Biology,” at 3:30 PM in BAG 261. instagram.com/p/CsJ8YNfPkcM/…
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