@cylee_tw
Account based inTaiwan
About this account
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Senior Epidemiologist & Research Head at Taiwan CDC since 2002. Principal Investigator of COVID and Emerging Infectious Diseases. Views are my own.
Taipei, Taiwan
Joined May 2009
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Cheng-Yi Lee, PhD. retweeted
9/18日、NYCから89件 (検体採取: 8/30~9/13)アップロードされ、そのうち9件がPJ.2.1でした。
7月のアウトブレイク以来、検出頻度はおおむね週1件程度で推移し、シンガポールと同様の経過を辿るかに見えました。しかし、今回の報告は、PJ.2.1がNYCに確実に定着しつつあることを示唆しています。
Cheng-Yi Lee, PhD. retweeted
BREAKING: NYS Covid cases continue to rapidly rise and even appear to be going straight up on the chart. 765 cases at a time, when most either do at home test or do not test at all.
Cheng-Yi Lee, PhD. retweeted
The rapid spread of PJ.2.1 in Spain 🇪🇸 raises an obvious question: What about the rest of Europe?
The answer: We largely don’t know.
Of 886 SARS-CoV-2 sequences collected in Europe since July 1 and submitted to GISAID, 671 are from Spain.
Much of the rest of Europe has gone dark on genomic surveillance.
6 new PJ.2.1 sequences from Spain 🇪🇸
Most patients were aged 55+, as expected. Two were hospitalized.
📍 4 — San Sebastián
📍 1 — Madrid
📍 1 — Bilbao
PJ.2.1 is likely circulating more broadly, but only 6 of 141 samples were PJ.2.1, suggesting it is not yet dominant.
#PJ21
Cheng-Yi Lee, PhD. retweeted
Hawai`i COVID Update 2026-9-15:
In today's updated data, as of 9/10/2026, SARS2 wastewater levels on Oahu have grown to:
• 105% of the summer 2025 peak in Ewa, and
• 83% of the summer 2025 peak in Honolulu.
and rising.
data.wastewaterscan.org/trac…
Cheng-Yi Lee, PhD. retweeted
とうとう爆誕したかもしれない「増殖力をキャッチアップした」BA.3.2ほにゃららのことは、向こうではBA.3.2 crypticと呼ぶようだ。
免疫逃避の強いBA.3.2の足が早くなった場合と
BA.3.2 CRYPTIC?
With (at last...) some Spike diversity - bit of an epistatic-looking cluster of changes?
@snpoehlm
@LongDesertTrain
REALLY hoping this is not another case of Marc discovering "Cryptic" that then turns out to be novel circulating saltation!
(PJ.2.1 in NYC...)
Cheng-Yi Lee, PhD. retweeted
NEW - Germany's former Chancellor Merkel suddenly reveals how Bill Gates exerted pressure on policymakers regarding vaccinations.
Cheng-Yi Lee, PhD. retweeted
Getting reports about a possible Ebola exposure involving an international traveler who wasn’t screened by CDC on arrival in Dallas.
The passenger later landed in Chicago, where CBP held the entire plane while CDC evaluated them.
Cheng-Yi Lee, PhD. retweeted
大阪大などが、新型コロナウイルス感染症やインフルエンザ肺炎の患者の体内で免疫が暴走し、自身を攻撃して全身に強い炎症を起こす「サイトカインストーム」を抑える新しい技術を開発
炎症を伴うさまざまな病気に応用できる可能性がある
news.yahoo.co.jp/articles/4a…
Cheng-Yi Lee, PhD. retweeted
【新型コロナウイルスの感染力】（2026年版）
🟥基本再生産数（R0：アールノート）＝何も対策を取らなかった場合の感染者が人に感染させる人数
🦠武漢株（2020）＝2.5～3.0
🦠デルタ株（2021）＝5～8
🦠オミクロン BA.1/BA.2（2021–22）＝8～10
🦠オミクロン BA.5（2022）＝10～12
🦠オミクロン XBB 系（2023–24）＝8〜10
🦠オミクロン JN.1（2024–25）＝8〜10
🚨【参考：他の感染症】
🦠季節性インフルエンザ＝1～3
🦠麻疹＝12～18
🦠ジフテリア＝6～7
🦠天然痘＝5～7
🦠ポリオ＝5～7
🦠風疹＝5～7
🦠流行性耳下腺炎＝4～7
🦠HIV/AIDS＝2～5
🦠百日咳＝12～17
🦠エボラ＝1.5～2.5
🦠SARS＝2～5
🟥実効再生産数（Rt）＝手洗い・マスク・フィジカルディスタンス・ロックダウンなどの対策を講じた場合の感染者が人に感染させる人数
💖科学的に正確な情報が必要な方に届きますように💖
#マスク着用 #手洗い #換気 #３密回避（密閉・密集・密接）
Cheng-Yi Lee, PhD. retweeted
PJ.2.1 might already be circulating in Germany
東京も...
新型コロナ 引き続き増加
東京都の定点把握 37週
9/7(月)～13(日)
※以下の記述での前週の値は全て前週発表時のものです
前週(発表時)との比較
定点当たり2.41←1.84(+31.0%
報告の実数1009←764(+32.1%
基幹定点での入院数26←41(-36.6%)
7週連続の増加
定点当たりの報告数2.41は第14波のピーク(2/2-8の週)の2.04を超え,去年夏から秋の第13波の終わり頃に相当します(ほぼ11か月ぶり)
年代別の報告数
・子ども
前週で倍増して,すでに第14波のピークを超えている10歳未満はさらに2割増加
これまで報告が少なく前週で４倍になった10代前半は今回はさらに３倍近い増加で,今年2月の第14波のピーク161に迫る数字
10代後半も今回倍増で第14波のピークを超えた
・おとな
50代と80歳以上が減った他は増加
70代は倍増
10代までは627←411←212←108←54←71
20代以上は382←353←232←187←106←107
画像1枚目と2枚目が全体の今回と前週の数字
3枚目は年代別の推移,4枚目がグラフです
都のサイト
survey.tmiph.metro.tokyo.lg.…
なお,インフルエンザも倍近い増加で定点当たりは9.53人(←5.46),流行の目安となる10に迫る勢い
コロナと併せて感染対策にご留意を!
Cheng-Yi Lee, PhD. retweeted
. @WHO’s 69th mpox situation report is available ⬇️
Global risk remains moderate. DG @DrTedros standing recommendation for #mpox have been extended to Aug 2027
@Chikwe_I @PeopleDocGeneva
who.int/publications/m/item/…
Cheng-Yi Lee, PhD. retweeted
新型コロナ 定点把握
埼玉県 (9/7-13)
年代別
子ども
もともと多かった10歳未満が4割以上増加,一昨年12月～去年2月の第12波に迫る多さ
10代前半と後半はこのところ少なかったが,今回は大幅に増加
おとな
減ったのは70代だけ(微減)で
それ以外は増加
80歳以上は4月以来,5か月ぶりに報告数が2桁になった
(続)
Cheng-Yi Lee, PhD. retweeted
埼玉県 新型コロナ 定点把握【大幅増加】
9/7(月)～13(日)の1週間の感染状況
新型コロナの定点当たり報告数 5.00人←3.02人
65.6%増加(6週連続で増加)
5以上になるのは去年9/29-10/5の週(第13波が減りだした頃))以来,11か月余ぶり
報告の実数では
14保健所管内で増加,2管内で変わらず,1管内で減少
年代別では10歳未満が4割増加
これまで報告が少なかった10代前半が2.4倍,同後半が4.7倍の大幅増加
大人も微減の70代以外は増加
一方,流行期が早く始まったインフルエンザは倍増
定点当たりの報告数が 9.10人←4.57人(+99.1%)
県の発表
pref.saitama.lg.jp/documents…
(続)
Cheng-Yi Lee, PhD. retweeted
BA.3.2 CRYPTIC?
With (at last...) some Spike diversity - bit of an epistatic-looking cluster of changes?
@snpoehlm
@LongDesertTrain
REALLY hoping this is not another case of Marc discovering "Cryptic" that then turns out to be novel circulating saltation!
(PJ.2.1 in NYC...)
WTH, I think I found a BA.3.2 cryptic (I hope it isn't circulating anyway).
Standard RBD + A435F, S438F, P463F.
Wonder if that improves ACE2 binding?
It was 100% of the sequence from one sewershed.
@LongDesertTrain
Cheng-Yi Lee, PhD. retweeted
Today two PJ.2.1 international US-airport seqs showed up from Cuba & Germany (Aug 31, Sept 1 collection), adding to the list of countries we've seen PJ.2.1 in. We've had ~zero recent seqs from Cuba or Germany, so this is, at the very least, a sign that PJ.2.1 is not rare there.
As Fede Gueli points out, @SolidEvidence's wastewater variant dashboard makes it clear that PJ.2.1 is the fastest-growing lineage in the US. I've inserted arrows pointing to some of the PJ.2.1 mutations. The farther above the dotted diagonal line, the faster the growth. 1/6
Cheng-Yi Lee, PhD. retweeted
Tracking emerging variants such as PJ.2.1 has become increasingly difficult as sequencing activity has declined.
This decline reflects shifting public health priorities and financial constraints.
However, the emergence of highly divergent variants such as BA.3.2, which disproportionately affects children, and PJ.2.1, which may have the potential for wider geographic spread, has clear public health implications.
These developments underscore the importance of maintaining at least a baseline level of genomic surveillance. #PJ21
A new PJ.2.1 detection in Murcia, Spain 🇪🇸.
Most detections so far have been reported from the Barcelona area. Beyond Barcelona, PJ.2.1 has also been detected in Oviedo and Murcia.
These cities are geographically distant from one another, suggesting that the variant is circulating in several parts of the country.
Most detections came through baseline surveillance. However, PJ.2.1 was also detected through sentinel ARI surveillance in a 1-year-old girl and an 82-year-old woman.
Thus, as expected, PJ.2.1 infection can also be associated with symptomatic respiratory disease.
Most PJ.2.1 detections in Spain so far have been reported in older adults, in agreement with data from Canada and the US. Let's see whether this pattern continues as more cases are identified. #PJ21
