Dion Dickman (@dion_synapse) header
Dion Dickman (@dion_synapse) profile picture

Synaptic plasticity in lab and life! Prof of Neuroscience @USC, homeostasis

Los Angeles, CA
Joined May 2017
Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)Photo by Dion Dickman (@dion_synapse)
We are starting a new Neuroscience graduate program at USC, details below, please consider applying!
Are you planning a PhD in neuroscience? The Department of Neurobiology at USC has launched a new PhD program, and we’re recruiting our first cohort. Our labs seek answers to: How animals learn, remember, and choose what to do. How synapses transmit signals and stay stable over a lifetime. How neural circuits are built, how they fail in disease, and can they be repaired? How the brain turns sensation into action. We investigate these questions at scales from single synapses to whole-brain networks, using molecular, genetic, physiological, imaging, computational, and behavioral approaches across model systems. Explore our labs: dornsife.usc.edu/neurobiolog… What you’ll get: Full funding: tuition plus a $43,000 annual stipend and health insurance A small cohort with direct faculty mentorship, where you’ll help shape a program as it grows Lab rotations across three faculty labs before you choose your thesis lab Los Angeles: a major research hub with S-tier climate, cultural vibrancy and global influence Applications due December 1, 2026. GRE optional. Application fee waivers available based on demonstrated need. Apply here: dornsife.usc.edu/neurobiolog… Any questions? Reply or DM and I’m happy to answer.
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Reposting this thread from John Tuthill, what an interesting story - adult Drosophila NMJs exhibit a diverse and heterogeneous molecular architecture compared to larvae! Great to be a part of this collaboration led by Anne Sustar! biorxiv.org/content/10.64898…
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This matters because tuning receptor composition (e.g., desensitization kinetics) may be how muscles specialize for different functions. The molecular identity of a synapse may be tailored to the biomechanics of the muscle it drives.
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These results overturned our previous assumption that NMJ function is uniform across fly development. A lot of work remains to understand the physiology and function of diverse NMJ synapses across different muscles. Once again, biology is way more complicated than we expected.
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Beyond thrilled to share my new paper out now in @PNASNews ! We asked: how do excitatory synapses detect a sudden hit to GluRs and rapidly restore transmission? They don’t just sense “less current” – they monitor the structural changes of GluRs and react. shorturl.at/Ctfff
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Excited to have this paper out in @PNASNews, where we interrogate the induction mechanism of rapid homeostatic signaling at synapses. Congrats to @ChengjieQ and the rest of the team! pnas.org/doi/10.1073/pnas.25…
Replying to @ChengjieQ
Synapses are more resilient than you might think! 💪When GluRs are weakened, the presynaptic neuron can compensate by releasing more neurotransmitters, keeping synaptic strength in a stable range. This retrograde process is called presynaptic homeostatic potentiation (PHP). 1/
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Excited to have this review out in @ELSneuroscience about synapses with diverse properties...although a bit concerned having "diversity" in the title! Congrats to @KaikaiHe24 ! sciencedirect.com/science/ar…
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Dion Dickman retweeted
Graduate school application deadlines are fast approaching! Come study Neuroscience in sunny California! With fabulous faculty: @dion_synapse @Don_B_Arnold @AndrewHires and others! See dornsife.usc.edu/neurobiolog… Apply here to USC Neuroscience by Dec 1. usc.liaisoncas.com/applicant…
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Headed to DC for study section today… wish me luck!
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Excited to just receive the news that I was promoted to full Professor! So grateful to everyone that traveled this journey with me, especially my awesome lab (past and present), friends/colleagues, and family! Can't wait to celebrate in person (last promotion was during covid!)
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Amazing visit the @VollumInstitute! So many outstanding scientists, great ideas, and new approaches! It was a true honor, thank you @Jiaxingli and all the other postdocs for the invitation! ❤️🙏🏼
Thank you for an incredible talk and engaging all-day interactions with trainees at the Vollum Postdoc-Invited Seminar! It was a blast discussing science, life, and AI:) @VollumInstitute @dion_synapse
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Ready excited about the visit tomorrow - what an honor to be invited by the Vollum postdoctoral researchers! 🙏🏼thank you @Jiaxingli !
The Vollum Seminar Series continues Thursday (10/17) with Dr. Dion Dickman presenting “Input-specific mechanisms distinguishing synaptic strength and homeostatic plasticity” at noon in M1441 of the Vollum. Hosted by Dr. Jiaxing Li. #OHSUResearch can stream from the intranet.
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We are recruiting a new technician to work on synaptic plasticity leveraging Drosophila genetics, please apply! usccareers.usc.edu/job/los-a…
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Bittersweet day in the lab as 2 great students graduate! @ChunJChien and Nancy Tran, congrats and best of luck at your next step!!
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