Cullen Lab for Neural Engineering, Neurotrauma and Regenerative Medicine | University of Pennsylvania
Philadelphia, PA
Joined October 2018
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Cullen Lab retweeted
Now that's a good-looking group! ๐ธ
Check out the new team photo for the @PennMedicine Department of Neurosurgery
Cullen Lab retweeted
Happy Thanksgiving from our #neurosurgery family to yours. We all hope you have a safe and happy holiday!
We are so proud of @MelanieHilman for successfully defending her thesis on Monday. Huge thanks goes to her committee Dr. Flavia Vitale, Dr. Foteini Mourkioti, @jboerckel and Dr. Dave Meaney. Wishing her all the best in her next chapter!โ
Cullen Lab retweeted
Our Advanced Materials Interfaces frontispiece is out! ๐ This is the first-ever image of an astrocyte interfaced with MXene nanomaterials ๐ง
* Our paper โก๏ธ doi.org/10.1002/admi.2025002โฆ
* Our full-page frontispiece โก๏ธ doi.org/10.1002/admi.70207
ALT This image shows Ti3C2Tx MXene flakes on the astrocyte membrane. Ti3C2Tx MXene is a two-dimensional nanomaterial with promising properties for application in bioelectronics. In this first systematic evaluation of astrocyteโMXene interactions, scanning electron microscopy reveals Ti3C2Tx adhering to astrocytes without causing any evident alteration of the membrane. Alongside viability, morphology, and calcium imaging assays, these findings establish for the first time the biocompatibility of Ti3C2Tx MXene with astrocytes. More details can be found in the Research Article by Flavia Vitale, D. Kacy Cullen, and co-workers (DOI: 10.1002/admi.202500261).
Cullen Lab retweeted
โจ I am beyond thrilled to share that our new paper has just been published in Advanced Materials Interfaces! We present the ๐ณ๐ถ๐ฟ๐๐ ๐๐๐๐๐ฒ๐บ๐ฎ๐๐ถ๐ฐ ๐๐๐๐ฑ๐ ๐ผ๐ณ ๐ฎ๐๐๐ฟ๐ผ๐ฐ๐๐๐ฒโ๐ ๐ซ๐ฒ๐ป๐ฒ ๐ถ๐ป๐๐ฒ๐ฟ๐ฎ๐ฐ๐๐ถ๐ผ๐ป๐
๐ doi.org/10.1002/admi.2025002โฆ
Congratulations to @D_Boufidis! Our new paper โAstrocyte Interactions With Ti3C2Tx MXene Flakes: Insights Into Viability, Morphology, and Functionalityโ is now online in Wiley Advanced Materials Interfaces: advanced.onlinelibrary.wileyโฆ
The Cullen lab members were honored to attend Dr. Robert Langerโs talk today at Penn. Listening to his pioneering research on tissue engineering and drug delivery systems was truly a privileged experience.
Cullen Lab retweeted
๐ข My first first-author paper, ๐๐ถ๐ผ-๐ถ๐ป๐๐ฝ๐ถ๐ฟ๐ฒ๐ฑ ๐ฒ๐น๐ฒ๐ฐ๐๐ฟ๐ผ๐ป๐ถ๐ฐ๐: ๐ฆ๐ผ๐ณ๐, ๐ฏ๐ถ๐ผ๐ต๐๐ฏ๐ฟ๐ถ๐ฑ, ๐ฎ๐ป๐ฑ โ๐น๐ถ๐๐ถ๐ป๐ดโ ๐ป๐ฒ๐๐ฟ๐ฎ๐น ๐ถ๐ป๐๐ฒ๐ฟ๐ณ๐ฎ๐ฐ๐ฒ๐, is now published in ๐๐ข๐ต๐ถ๐ณ๐ฆ ๐๐ฐ๐ฎ๐ฎ๐ถ๐ฏ๐ช๐ค๐ข๐ต๐ช๐ฐ๐ฏ๐ด! ๐ง โก
๐ Read it here: doi.org/10.1038/s41467-025-5โฆ
Exciting news from our lab! Our PhD student โฆ@D_Boufidisโฉ presented our groundbreaking research and the role of #sciencediplomacy at the Greek Embassy in Washington, D.C.! We are proud to see our labโs work spotlighted on an international stage! โฆ@GreeceInUSAโฉ
Cullen Lab retweeted
To investigate the cellular changes that occur after a mild TBI, the @dkcullenlab caused an acceleration-induced TBI in a pig model, recreating the biomechanical loading parameters associated with concussion on a brain similar to humans.
@Biomed_MDPI
โก๏ธ spr.ly/6014U8yUa
Excited to see the new Wofford lab!!! Such a proud moment for the Cullen lab to see one of our postdocs achieving this milestone. Future students, keep an eye for positions in this lab working on traumatic brain injury and neuroinflammation under the leadership of @KateWofford.
The ribbon cutting ceremony for the Neuroinflammation and Immunomodulation Lab at @PennNSG! ๐ When the stores are out of ribbon, you use a neuron!
We're ready to dive into groundbreaking research to understand and harness the immune system after brain injury.
Cullen Lab retweeted
Thrilled to join @PennNeurosurgery as an Assistant Professor and open the Neuroinflammation and Immunomodulation Lab! We're diving deep into understanding and controlling the immune system after brain injury. ๐ง ๐ฉ๐ปโ๐ฌ #Neuroscience #Research #BrainHealth #PennMedicine #newPI
Cullen Lab retweeted
Now that's a good-looking group! ๐ธ
Check out the new photo for the @PennMedicine Department of #Neurosurgery
TBI gang of the lab had an amazing time at the @Neurotrauma conference in SF. #NNS2024
Cullen Lab retweeted
Axons in brains of female mammals may be more vulnerable to damage, says new research from Douglas Smith, Professor of Neurosurgery and member of the #PennBioengineering Graduate Group.
bit.ly/3xkb44E
ALT Top: Axons in female and male subject brains Bottom: damaged axons in male and female brains after injury (Credit: Penn Medicine)
Cullen lab is having so much fun at the @Neurotrauma conference!!! We had an amazing time at the poster presentations by @KateWofford and Dan Han, and meeting former students.
Cullen lab is hiring!!! The postdoctoral researcher will manage aspects of the studies that will include iPSC derived neural and skeletal myocyte culture, bioprinting, optogenetic transduction and functional assessment in vitro and in vivo. Check this out for more details -
Weโre thrilled to announce that our very own Dimitris has won the Outstanding Service Award at @PennEngineering ! His dedication to enhancing the well-being of the engineering community exemplifies the spirit of leadership and service. Congratulations, Dimitris! ๐๐ #PennPride
Our collaborative study led by @hailong_song shows differences in male and female brains and effect on cognitive deficits due to the structural differences. Check out for more details -
pennmedicine.org/news/news-rโฆ
Cullen Lab retweeted
I am thrilled to share our paper โSex differences in the extent of acute axonal pathologies after experimental concussionโ, now available at Acta Neuropathologica!!
link.springer.com/article/10โฆ
