Elizabeth Pando Rau (@epr82) header
Elizabeth Pando Rau (@epr82) profile picture

Elizabeth Pando Rau

@epr82

MD, PhD. HPB Pancreatic surgeon. Hospital Clinic Barcelona @hospitalclinic Cáncer Páncreas @barnaclinic

 Barcelona, España
linkedin.com/in/elizabeth-pando-rau
Joined March 2011
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Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)Photo by Elizabeth Pando Rau (@epr82)
Happy to announce that I’m starting a new stage as a surgeon at @hospitalclinic de Barcelona, to continue working in multidisciplinary care for borderline and locally advanced pancreatic cancer. @ernest_hidalgo @MacarullaTeresa @olguicsMR
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IDIBAPS (@idibaps) profile picture
IDIBAPS@idibapsOct 27
IDIBAPS SEMINAR From clinical insights to research: exploring hepatobiliary surgery and cholangiocarcinoma 📆03/11 - 14.30h 🗣️Masahiko Kinoshita, Osaka Metropolitan University 📍Auditori Esteve, CEK 👉f.mtr.cool/w554okqced
Image from IDIBAPS (@idibaps)
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IDIBAPS (@idibaps) profile picture
IDIBAPS@idibapsOct 23
IDIBAPS SEMINAR From clinical insights to research: exploring hepatobiliary surgery and cholangiocarcinoma 📆03/11 - 14.30h 🗣️Masahiko Kinoshita, Osaka Metropolitan University 📍Auditori Esteve, CEK 👉f.mtr.cool/jr76t6eayb
Image from IDIBAPS (@idibaps)
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Elizabeth Pando Rau retweeted
The Lancet (@TheLancet) profile picture
The Lancet
@TheLancetOct 27
Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest malignancies. In @LancetGastroHep, a Review evaluates the clinical development of therapeutic cancer vaccines in PDAC: spkl.io/60107kQ3K
Antigen sources and vaccine platforms in PDAC. Created in BioRender. Chap, B. S. (2026) https://BioRender.com/7xdlrqt. (A) Patient-derived tumour tissue can provide multiple antigen sources, including whole-tumour lysate, TAAs, TSAs, and neoantigens. These antigens undergo selection and, when applicable, computation epitope prediction to prioritise immunogenic targets, which are subsequently incorporated into a final vaccine formulation. (B) Several vaccine platforms are being explored in PDAC, including cell-based and dendritic cell-based vaccines, mRNA-based and DNA-based vaccines, peptide and protein vaccines, and microorganism-based approaches, all aiming to induce tumour-specific T-cell responses against the pancreatic tumour.

ALT Antigen sources and vaccine platforms in PDAC. Created in BioRender. Chap, B. S. (2026) https://BioRender.com/7xdlrqt. (A) Patient-derived tumour tissue can provide multiple antigen sources, including whole-tumour lysate, TAAs, TSAs, and neoantigens. These antigens undergo selection and, when applicable, computation epitope prediction to prioritise immunogenic targets, which are subsequently incorporated into a final vaccine formulation. (B) Several vaccine platforms are being explored in PDAC, including cell-based and dendritic cell-based vaccines, mRNA-based and DNA-based vaccines, peptide and protein vaccines, and microorganism-based approaches, all aiming to induce tumour-specific T-cell responses against the pancreatic tumour.

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A new vaccine continues to show potential as a ready-made treatment for pancreatic cancer, according to a study co-led by MSK researchers. MSK's @EileenMOReilly presented phase 2 results from AMPLIFY-7P at #ESMO26. The vaccine targets KRAS mutations, which are found in more than 90% of pancreatic cancers. 99% of patients receiving the vaccine developed cancer-fighting immune T cells. Patients with the strongest immune responses had the lowest recurrence rates. “Having a vaccine that’s ‘off-the-shelf’ would make it easier, faster, and less expensive to treat a larger number of patients,” says Dr. O’Reilly. “This gives hope for people with pancreatic cancer who have been out of effective treatments when their disease returns.” Learn more: bit.ly/3VSsO3h
Image from Memorial Sloan Kettering Cancer Center (@MSKCancerCenter)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Oct 24
Lymph node-targeted, mKRAS-specific amphiphile vaccine in #PancreaticCancer: the randomized phase 2 AMPLIFY-7P trial (@ElicioTx) nature.com/articles/s41591-0… Most important panel: in post surgical setting ctDNA positivity is pivotal driver of disease free survival, agnostic to vaccine
Image from Anirban Maitra (@Aiims1742)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Oct 23
Tango reports 82% tumor response rate in trial of combo therapy (Daraxonrasib plus vopimetostat) for advanced #PancreaticCancer at #ESMO26 statnews.com/2026/10/23/esmo… Reduced toxicity data is particularly important as a lower Daraxonrasib dose can be used.
Tango reports 82% tumor response rate in trial of combo therapy for advanced pancreatic cancer

Tango reports 82% tumor response rate in trial of combo therapy for advanced pancreatic cancer

An experimental drug combination led to tumor responses in 82% of patients with a certain type of advanced pancreatic cancer, Tango Therapeutics reported.

statnews.com
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Oct 24
Striking a Nerve in #PancreaticCancer: Unraveling the Crosstalk Between Tumor Cells and Neurons aacr.org/blog/2026/10/23/str…
Image from Anirban Maitra (@Aiims1742)
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Hospital Clínic (@hospitalclinic) profile picture
Hospital Clínic
@hospitalclinicOct 22
🚀 El #Clínic continua avançant en innovació i transformació digital. 💪 Ja som el 28è hospital intel·ligent del món, segons el rànquing World's Best Smart Hospitals 2027 de Newsweek i Statista, i el primer de Catalunya en aquesta classificació. 💚 Gràcies als professionals que ho fan possible. 🔗 f.mtr.cool/367oeb7ami #Newsweek #SmartHospitals #Innovació #SalutDigital #TransformacióDigital #HealthcareInnovation
Image from Hospital Clínic (@hospitalclinic)
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Arndt Vogel (@ArndtVogel) profile picture
Arndt Vogel
@ArndtVogelOct 22
The ESMO Scale for Clinical Actionability of Molecular Targets, version 2 (ESCAT v2): an evidence-based framework for ranking alterations as actionability and resistance biomarkers in precision oncology @Annals_Oncology doi.org/10.1016/j.annonc.202… 👉helpful for interpreting actionability and decision making @myESMO @ASCO
Image from Arndt Vogel (@ArndtVogel)
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Marc Besselink (@MarcBesselink) profile picture
Marc Besselink
@MarcBesselinkOct 20
🇪🇺Europe is stepping up in the treatment of #PancreaticCancer with the first Multidisciplinary #Guidelines and the #PALACROS project 🔥 🤝Involving over 30 societies and patient organizations, 15 countries and 60+ centers across Europe 🙌Thanks to @my_ueg (14,000+ attendees!) for highlighting these developments! 🔗#PALACROS including the #PREOPANC4 RCT #PULSE and #PIVOTAL trials: pancreaticcancereurope.eu/pr… 🔗#Guidelines protocol: pancreaticcancereurope.eu/pr…
Image from Marc Besselink (@MarcBesselink)
Image from Marc Besselink (@MarcBesselink)
Image from Marc Besselink (@MarcBesselink)
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OncoDaily GI (@OncoDailyGI) profile picture
OncoDaily GI
@OncoDailyGIOct 16
5 Pancreatic Cancer Trials to Watch at ESMO 2026 The ESMO Congress 2026 will feature new pancreatic cancer data across resected, borderline resectable, locally advanced, and metastatic disease. Trials to watch: • RASolute 302 — Additional subgroup analyses of daraxonrasib vs chemotherapy in previously treated metastatic pancreatic adenocarcinoma • AMPLIFY-7P — Randomized phase II results with ELI-002 7P vs observation in resected pancreatic ductal adenocarcinoma • MASTERPLAN — mFOLFIRINOX with or without SBRT in patients with high-risk, borderline resectable, or locally advanced pancreatic cancer • HRS-4642 — Preliminary phase II results with HRS-4642 + chemotherapy ± adebrelimab as perioperative therapy in KRAS G12D-mutant pancreatic cancer • INCB161734 — Safety and efficacy of INCB161734 in combination with chemotherapy in advanced or metastatic pancreatic ductal adenocarcinoma Together, these five presentations will provide additional data across resected, locally advanced, and metastatic pancreatic cancer, including several RAS-directed treatment strategies. @AHollebecque @WainbergZev @EileenMOReilly 📎oncodaily.com/gastrointestin… #ESMO2026 #KRAS #OncoDaily
Image from OncoDaily GI (@OncoDailyGI)
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Giovanni Marchegiani (@Gio_Marchegiani) profile picture
Giovanni Marchegiani@Gio_MarchegianiOct 17
✋ Discontinuing surveillance of Trivial IPMN is safe! Out in @UEGJournal 👍 25% would be discharged / No HGD missed! 💸 Money saved depend on local health care system 🍇 Prospective evaluation ongoing with @MarcBesselink @DeMadaria and others 🙋🏼‍♂️ onlinelibrary.wiley.com/doi/…
Image from Giovanni Marchegiani (@Gio_Marchegiani)
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ACanPan (@ACanPan) profile picture
ACanPan@ACanPanOct 17
Celebramos la recomendación de la EMA pero el tratamiento todavía no está disponible en España, pedimos que estos trámites se desarrollen con la máxima agilidad posible, evitando retrasos para los pacientes que podrían beneficiarse de esta innovación. asociacioncancerdepancreas.o…
Image from ACanPan (@ACanPan)
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Teresa Macarulla (@MacarullaTeresa) profile picture
Teresa Macarulla@MacarullaTeresaOct 10
In Lisbon with our pancreatic surgery and medical oncology team from Hospital Clínic Barcelona at the 3rd Botton-Champalimaud Conference. Good discussions, new ideas and time together outside the hospital @hospitalclinic @idibaps
Image from Teresa Macarulla (@MacarullaTeresa)
Image from Teresa Macarulla (@MacarullaTeresa)
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At @ChampalimaudF PDAC conference, @chiaro_del reviews radiotherapy in LAPC: no proven OS benefit, higher complication risk. Seek a second opinion to assess surgical resectability before radiotherapy in locally advanced PDAC.
Image from Elizabeth Pando Rau (@epr82)
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Present at the 3rdInternational Pancreatic Cancer Conference @ChampalimaudF, with @MacarullaTeresa presenting the PANOVA-3 results in LAPC. @idibaps & @hospitalclinic at one of the key global meetings in the field. @olguicsMR @MaciasDeclara @Florian_Castet @vicenttianfr
Image from Elizabeth Pando Rau (@epr82)
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Arndt Vogel (@ArndtVogel) profile picture
Arndt Vogel
@ArndtVogelOct 5
NGS of ctDNA for Precision Medicine in Advanced Biliary Tract Cancers ClinicalCancerReseach doi.org/10.1158/1078-0432.CC… 🔎10,937 pts 👉90% feasible vs 50% tissue 👉TAT 8 vs 27 days 👉83% ESCAT-I concordance 👉ctDNA prognostic: mOS 27.7 vs 13.6 mo 🧐ctDNA can expand access, accelerate precision medicine @myESMO @EASLnews @ILCAnews
Image from Arndt Vogel (@ArndtVogel)
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Cancer Discovery (@CD_AACR) profile picture
Cancer Discovery@CD_AACRSep 26
Read the recent review article by #AACRpan26 Conference Cochair Eileen M. O’Reilly, “Pancreatic Cancer: Translating Tumor Biology into Actionability.” aacrjournals.org/cancerdisco… #OpenAccess @EileenMOReilly
Image from Cancer Discovery (@CD_AACR)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Sep 26
With all the focus on KRAS at #AACRPan26, a timely commentary in @CD_AACR Targeting RAS for #PancreaticCancer Interception aacrjournals.org/cancerdisco… @hopkinskimmel crew (@Sandra_Misale @lauradelongwood @NeehaZaidi @DrLizJaffee @alisonpklein) The time is right for these trials!
Image from Anirban Maitra (@Aiims1742)
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Anirban Maitra (@Aiims1742) profile picture
Anirban Maitra@Aiims1742Sep 26
Our review is online at @Gut_BMJ concurrent with #AACRPan26 Metastatic #PancreaticCancer: from human disease to preclinical modelling gut.bmj.com/content/early/20… Co-authored with @jiminmin_v @PeterYuMD @Perlmutter_CC @nyulangone & colleagues from @CNIOStopCancer
Image from Anirban Maitra (@Aiims1742)
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