James retweeted
Mining software doesn’t have to feel like mining software.
Manage a mine like you’re playing a strategy game.
Built with Opus 5.5
James retweeted
Former Scale AI founder and newly appointed @Meta Chief AI Officer @alexandr_wang dropped a bombshell during his YC conversation with @garrytan, and you could almost hear the tech leadership world go quiet.
He said Meta has already seen this internally:
Build the right agentic loop, give it an evaluation system and metrics that let it optimize itself, and a group of AI agents can complete more work than a team of 100 senior engineers.
And they do it “very easily.”
But the most interesting part wasn’t the 100-engineer comparison.
It was how simple the system underneath it actually is.
You’d expect some insanely complex, almost alien architecture powering a swarm like this.
Instead, Wang described it with a few almost comically basic words:
“Markdown files, cron jobs, goal, metrics, data.”
Once you strip away the hype, the implications for traditional software engineering become pretty clear:
1️⃣ It’s not that the models are magically smarter. The eval loop is doing the heavy lifting.
Traditional approach: humans write prompts, run the code, inspect the output, and hope nothing broke.
Meta’s approach: turn the business goal into something a machine can score automatically.
The agent submits its work. The system runs tests, calculates metrics, finds what’s wrong, and sends it back for another pass. Repeat until it passes.
Nobody has to babysit every step. The metric becomes the supervisor.
2️⃣ The real alpha is burning 1,000x more tokens inside the feedback loop.
A lot of people are still optimizing for the cost of a single AI call.
The frontier labs are playing a different game: spend 1,000x or even 1,000,000x more tokens in the background so agents can constantly review, rerun, challenge, and verify each other’s work until they reach a reliable business outcome.
Token cost is fixed. The payoff is a pipeline that keeps running.
3️⃣ Memory doesn’t need some fancy database.
Persistent memory can live in Markdown files.
Scheduling can be handled by the server’s built-in cron jobs, running overnight.
The simpler the scaffolding, the more robust the system can be. Less infrastructure also means fewer ways for context to fall apart.
This is a pretty brutal change in how technical organizations work.
The ceiling for a tech lead used to be partly about how many people they could manage, how many meetings they could sit through, and how many teams they could coordinate.
The leverage for the next generation of technical leaders may look very different:
Can you turn a messy business objective into a rigorous set of metrics that an AI can evaluate automatically?
If 100 people’s output can be replaced by a few cron jobs, Markdown files, and a well-designed eval loop, the era of “just take the ticket and write the code” is coming to an end.
The people who can design the evals and orchestrate the swarm aren’t just holding a new tool.
They’re effectively running a virtual company.
James retweeted
im increasingly convinced that the best way to bet on a particular sector is simply to own the top 1 or 2 dominant players. the laggards may feel cheap and u tell urself they have much more room to grow, but they r often at a massive disadvantage in terms of economy of scale and network effects. good companies stay good and bad companies stay bad.
James retweeted
Extremely interesting writeup -
AI accelerating science is critical, but it doesn’t directly address the bottleneck of *human* clinical trials.
Need AI w predictive validity for efficacy in humans (Phase II trials)
& that AI requires massive public datasets for human biology!
Tech has produced several trillion-dollar companies. Biotech has produced none. If I were completely impartial to what disease I treat or what modality I use, could any of the existing company-building strategies create a trillion-dollar outcome? This essay is a set of musings on the mental models behind building successful biotechs, on what might get the industry off “hard mode,” and on why age-related diseases are probably pharma’s only real salvation - yet also the place where most of our existing lessons are of no use.
(link in comments)
James retweeted
This is big. OpenAI and Retro used a custom model to make cellular reprogramming into stem cells ~50× better, faster, and safer. Similar Wright brothers’ glider to a jet engine overnight.
We may be the first generation who won't die.
Let's take a look at what they did. 🧵
James retweeted
The way new entrants view btc at $120,000 is the same way I viewed it at $1,000 in 2017
“I can never own enough of this to make it matter”
It’s literally 100x more true now, don’t let the maxis fool you
James retweeted
Forte brings protocol composability and native automation directly to the network.
Forte is coming:
• Testnet: September 17
• Mainnet: October 22
Watch @dete73 announce Forte, the future of consumer crypto and AI, at the @EthGlobal Pragma main stage⤵️
James retweeted
Just heard from the team in NYC that @flow_blockchain was the most built on out of all platforms at @ETHGlobal , not just L1/L2 chains 🤯
Seemed like the people liked your talk @dete73
Forte (& friends) coming October 2025 to put Flow-powered apps and agents in every pocket 🤖
James retweeted
New themes just dropped in the editor
- Dune Dark
- Tokyo
- Light
- Dark
Let me know which ones you'd like to see me create next
James retweeted
Agentic mode in the chat side bar - can read and write files available in the notebook instance
James retweeted
Maybe we proved memecoins are the best expression of social tokens
Messari @MessariCrypto were correct on this back in 2022
"New Token Distribution Mechanisms Could Trigger Bull Market"
Though it wasn't social tokens it was meme coins on platforms like @pumpdotfun
James retweeted
The game's greatest Moments on the world's biggest stage.
Starting today, @NBATopShot on @flow_blockchain is tradable on OpenSea.
James retweeted
Your AI agents and platforms can now access the entire Flow docs, cadence language reference and dozens of up-to-date educational sources by supplying a single url: github.com/onflow/Flow-Data-….
It automatically updates daily and continuously improves with a robust feedback loop that even parses Q&A in traditionally closed environments (like discord).
James retweeted
BIG NEWS: @opensea is live on Flow 🌊👋
Welcome OpenSea to Flow blockchain and the Flowverse
OS2 open beta is now live:
• A fully reimagined product built entirely from the ground up, for collectors and pros
• NFTs 🤝 tokens, brought together in one place
• Brand new, beautiful ways to explore — beyond just the floor
• 14 chains (welcome @flow_blockchain, ApeChain by @apecoin, @soneium by @Sony BSL, and @berachain) with more on the way
• Native cross-chain purchasing
• 0.5% marketplace fees and 0% swap fees on the platform for launch
• Rewards for all user types
And yes, $SEA is coming.
Try the open beta at opensea.io/os2
James retweeted
GREEN CON 🌊 is finally here!
It's time to discover:
-Consumer Web3
-Crescendo Upgrade
-Rewards Season 1
-Amazing dApps built on Flow
Powered by @flow_blockchain & @RugRadio
Full Lineup👇👇
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