George K. Mathew retweeted
Replying to @RamaswmySridhar
I don't think we should fight. The two companies are complementary. Since you're not doing this AI stuff, I really think Snowflake should consider getting its AI tokens through Databricks. You can get both cheap OSS models as well as frontier (OAI/Ant/Gemini/Grok) models from our platform. It all goes through Unity Gateway which has Smart Routing, Budgets, and Access Control. You can even use Omnigent with any harness, including CoCo. Most of our customers used this to reduce token spend ~30% last few months while token count went up. Genie lets you then track, control, manage that spend, all your financials, marketing, etc. Quick POC?
George K. Mathew retweeted
anthropic’s acquisition of mithril has me thinking more broadly about whether ai will add more value in drug discovery by optimizing molecules for selected targets or helping us rethink targets as data comes in from clinical trials.
like optimizing code vs revisiting architecture. both matter but which will ultimately contribute more to better outcomes for patients?
George K. Mathew retweeted
Our newest decision model is the world's best decision model.
Introducing GLiDE v1.2, the #1 model on the @huggingface Decision Index.
With an overall score of 71.5, GLiDE v1.2 also has one of the lowest calibration errors on the entire Decision Index, meaning its confidence more closely reflects how often its answers are correct.
Beyond improved benchmark performance, it also adds support for multimodal inputs, enabling decision-making using text, JSON, and images.
We are excited to release the model weights on Hugging Face. For hosted inference, you can also run GLiDE v1.2 through the Fastino API at $0.04 / million input tokens.
Use promo code GLIDEIS1 for $10 in API credits.
Model weights: huggingface.co/fastino/GLiDE
API: agent.fastino.ai
Blog: fastino.ai/blog/training-gli…
George K. Mathew retweeted
The best decision model in the world. GLiDE v1.2 is here (and it’s multimodal).
#1 on the @huggingface Decision Index, beating the next best model by 1.7 points.
The benchmarks are genuinely impressive:
- 71.5 full score
- 82 ms latency on NVIDIA RTX PRO 6000
- 1.9% calibration error on held-out decisions (one of the lowest on the index)
This model is smart, fast, well-calibrated, and open weight. Everything a good decision model should be. We’ve also dropped our pricing to $0.04 / million input tokens.
Try it today. Use promo code GLIDEIS1 for $10 in API credits.
API: agent.fastino.ai/
Weights: huggingface.co/fastino/GLiDE
George K. Mathew retweeted
Context is the moat! Announced on stage that Sweep was just acquired by @ServiceNow! Another great summit by @insightpartners. @gkm1
George K. Mathew retweeted
Thank you @insightpartners for another awesome AI founder dinner!!
George K. Mathew retweeted
MyPoV; here with @gkm1 @insightpartners Enterprise AI Summit
The economics of a Neolab.
A neolab is loosely defined as a startup of AI researchers who raises a lot of money pre-production to be able to finance GPU compute to take on a large AI problem.
To buy 1000 GB300s or ~14 NVL72 racks will set you back $125-150M for 3yrs with 15-30% upfront. That’s about ~2-2.5MW.
Thats about enough to do 10^25 flops a quarter and get to a GPT-4 level model which is 1-2 OOMs off frontier for pretraining.
If you post-train on a great open source model, you have a better chance of getting to frontier. The risks are a) you need to spend millions on RL environments too and b) being lapped by another model release while being tied to a base model.
For this to payback, you need to give your customers a better and ideally cheaper inference service than a base model and serve them for long enough to recoup your large investment. Even at 50% margin on inference, to recoup $10M in training means serving ~10T tokens (!) if you price like Fable / Astra given a standard cache read / input / output split ($2/M blended). And you have to justify being better than a release like Opus 5.5 which is even cheaper. Often, you end up charging your customers a huge premium in terms of platform fees and compute fees on top of pure inference.
Meanwhile, every hour you’re not utilizing your GPUs you are burning money so you typically resell this compute back to a broker or run inference for open models / resell spot instances. At below a ~60% utilization on spot, you will still lose money.
Add to that insane cost of talent.
So what can you do with the compute?
- Not play the model game at all.
- Play an entirely different model game (Jev, World Labs) that if big labs played, would either a) cannibalize their business or b) be incrementally not significant revenue c) would cause too much distraction from the main main thing
- Acquire a proprietary data set (Peridodic Labs) in enough volume in a domain of usefulness to eclipse frontier quality. Often happens in robotics, biology, chemistry.
If you do overcome the challenge of building a model that is useful and well priced beyond big labs models, given the huge price of compute, you still need to play in an area where the revenue / compute ratio is signficant and market demand is large enough to payback your compute spend.
It is a difficult game.
George K. Mathew retweeted
Introducing GLiNER2.5-Decide, our new 340M parameter open weight, encoder-based decision model.
GLiNER2.5-Decide is built for fast, deterministic classification. The model evaluates a set of user-defined typed questions and rules, and jointly decodes their answers, returning structured decisions with probability distributions and confidence scores.
We evaluated the model’s performance on Fast Decisions, an unseen, internally generated classification suite based on 17 datasets testing real-world use cases across routing, triage, classification, sentiment, and content understanding.
Measured against similar decision models, GLiNER2.5-Decide leads in 9 of the 17 datasets, achieving the highest average score:
- GLiNER2.5-Decide: 60.1%
- SemIf: 56.4%
- JevK5: 57.5%
- Laya: 46.6%
This performance makes the model a strong fit for use cases like tool calling, model routing, browser and computer use, and LLM-as-a-judge.
GLiNER2.5-Decide’s lightweight encoder architecture makes it easy to fine-tune the model for specific tasks, while being efficient enough to run locally on consumer-grade CPUs or in air-gapped environments, giving users greater control over where their data goes and where the model runs.
To make building and experimenting with GLiNER2.5-Decide as easy as possible, we're also offering hosted inference. You can now use our API to run inference and fine-tune GLiNER models on specialized tasks right inside your own coding agent: agent.fastino.ai
As with previous models, we’re also releasing the model weights on @huggingface under the Apache 2.0 license: huggingface.co/fastino/GLiNE…
George K. Mathew retweeted
bro mogged the absolute living shit out of dario with that handshake.
GLPs and the great twinkification have been a disaster for the technology class.
benioff is the last alpha remaining
Live: @DarioAmodei x @Benioff
The @AnthropicAI co-founder & CEO joins us at @Dreamforce for a conversation worth hearing ☁️
We’re sharing a solution to the Navier-Stokes Millennium Prize Problem, one of the deepest problems at the frontier of mathematics.
The proof was produced by a group of agents, using an OpenAI next-generation model significantly more capable than GPT-6 Astra.
The problem concerns whether the description of smooth three-dimensional fluid motion modeled by the Navier-Stokes equations can break down. It has remained unresolved for roughly 90 years.
George K. Mathew retweeted
Founders, don't forget to gently ask your board members if they have had a root canal without novocaine.
We need to know if they are cut out for the next stage of our growth.
George K. Mathew retweeted
I believe Gusto was the first company to mandate “no outside footwear” inside the office, but seeing this more and more in SF.
FWIW, I’m a fan :) but any company that mandates this, must make it up with really cool looking and comfortable slippers / socks etc (Gusto socks were/are so good).
Get your slippers on and join us for a walk around our SF headquarters, where we're doing it all with Devin. Even ordering our morning coffee.
cognition.com/careers
George K. Mathew retweeted
Based on OAI Friar's comments on CNBC today that OAI ARR is +35% QTD, implies ~250% y/y growth in August, an acceleration and 12 month high
George K. Mathew retweeted
In collaboration with @nvidia we're releasing two new open weight models: Fastino-Nemotron-3.5-Lightning-Finance and Fastino-Nemotron-3.5-Lightning-Healthcare.
Working closely with the Nemotron team, we developed both models on Nemotron 3.5 Lightning using the Fastino Fine-Tuning Agent, which autonomously ran the entire post-training pipeline. The base model was highly responsive, with the agent reaching substantial gains across both domains with compact datasets alone.
- Fastino-Nemotron-3.5-Lightning-Finance excels at numerical reasoning, research, and summarization over financial concepts and documents. When evaluated, the fine-tuned model increased FinQA execution accuracy by 43.37 points (15.86% to 59.23%), and increased 7.81 points (from 49.65% to 57.46%) on BizFinBench.
- Fastino-Nemotron-3.5-Lightning-Healthcare specializes in clinical conversation quality, summarizing notes and discharge documentation, and extracting medical concepts from unstructured text. In post-training, the Fastino Fine-Tuning Agent improved performance by a margin of 4.28 points on HealthAdminBench (from 25.67% to 29.95%) and 5.09 points on MedCalc-Bench (from 49.09% to 54.18%). It also increased flag accuracy on MEDEC by 11.32 points, beating Opus 4.6 and beating Muse Spark by 0.98 points.
Both models are available on @huggingface under the Apache 2.0 license:
- huggingface.co/fastino/Fasti…
- huggingface.co/fastino/Fasti…
Today we are also releasing the Fastino Fine-Tuning Agent in private preview, which you can sign up for access to here: fastino.ai/nvidia-collaborat…































