We study macrophages! We aim to understand and reshape macrophage immunometabolism to improve function and disease outcome. 🧫🔬🥼🧑🔬 🦠🧑💻🏥 #playforward
Amsterdam UMC, VUmc
Joined September 2019
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Jan Van den Bossche Lab retweeted
#Throwback
COMMENT | J Van den Bossche et al.
A call for accessible tools to unlock single-cell immunometabolism research
nature.com/articles/s42255-0…
Welcome to the #EMDS2025 38th European Macrophage & Dendrric Cell Society meeting. If the speakers are as nice as the venue, we’ll have a fabulous time in Edinburgh – at Edinburgh, Scotland
Jan Van den Bossche Lab retweeted
#Throwback
COMMENT | J Van den Bossche et al.
A call for accessible tools to unlock single-cell immunometabolism research
nature.com/articles/s42255-0…
No (innate immune) training without lactate…
I was invited by @MolecularCell to write a spotlight paper and discuss the recent work by Mihai Netea and colleagues in @CellCellPress on lactate production and downstream histone lactylation in the induction of trained immunity ⬇️
The abstract submission for the 2025 EMDS meeting in Edinburgh is open: emds2025.com/
I very much look forward to this conference and finally visiting Schotland for the first time 😍
Jan Van den Bossche Lab retweeted
Superb study of the effect of Trypanosomiasis infection on Kupffer cell function even weeks after cure and elimination of the parasite. Beautiful work from Jo Van Ginderachter and @MovahediTeam labs #EMDS2024. 🤩🤩🤩🤩🤩
Jan Van den Bossche Lab retweeted
Joining 🦋 @martinguilliams.bsky.social
Let’s see if we can #EMDS2024 Vienna #macrophage and #dendriticcell fans there!
Supported by @ImmunoMetEurope, @ImmunoMetNet, @BSI_immunomet, @ImmunoMet @immunemet, @SocietyEuropean and others working on immunometabolism, the aim of the Immunometabolism journal @Immunometaboli2 is to further grow and to become THE go-to journal in this exciting field
Our journal welcomes short commentary articles to put recently published high-impact work in a broader perspective. 🥳🥳🥳Interests in writing a commentary, contact our EiC Professor Jan Van den Bossche
@immunometlab and the EB member Professor Sarah Dimeloe @SarahDimeloeLab
A potential immunometabolic effect of antidepressant drug SSRI❔⬇️
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SLC13A3 story 1 (the beneficial one ✅): SLC13A3 was recently discovered to be an itaconate importer that improves hepatic antibacterial innate immunity
cell.com/developmental-cell/… @Dev_Cell
SLC13A3 story 2 (the detrimental one 🚫): Itaconate import into cancer cells via SLC13A3 was even more recently discovered to impair anti-tumor immunity by making tumors resistant to ferroptosis
cell.com/cancer-cell/fulltex… @Cancer_Cell
Next-generation immunotherapy opportunities using “T-linker” ⬇️
A linker-based platform integrates multiple therapeutic modules into a single ‘Multi-TAC’, which can engage multiple tumor-targeting immune cells within the tumor microenvironment cell.com/cell/fulltext/S0092… #NBThighlight
Jan Van den Bossche Lab retweeted
📢Last weeks #immunometabolism discoveries @Bims_BiomedNews 👇👇👇
biomed.news/bims-imicid/2024…
Highlights:
I) CENCAT - a new tool for probing immune cell metabolic states
II) Cholesterol synthesis drives the SASP and neurotoxicity in a patient stem cell-derived model of MS
CENCAT; an immunometabolic profiling tool that blends the @SCENITHmetab approach with BONCAT click chemistry to measure metabolic dependencies of cell subsets
@CellRepMethods paper online now ➡️ cell.com/cell-reports-method…
Jan Van den Bossche Lab retweeted
📢Last weeks #immunometabolism discoveries @Bims_BiomedNews 👇👇👇
biomed.news/bims-imicid/2024…
It's a big one this week, check it out!
