
@primateriacom, EE @stanford and berkeley, @alliance, train software @ycombinator s19
Palo Alto
Joined February 2018
- Tweets336
- Following532
- Followers6.2K
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At @primateriacom, we are building chemical simulators that reflects reality, so we can run experiments for new discoveries entirely on a computer.
Are coding agents good enough to help us get there? To find out, we used experimental results to test their work on reengineering existing simulators.
Introducing Wavefunction bench: primateria.com/blog/wavefunc…
Emerson Hsieh retweeted
I continued to be amazed by Emerson and Morris and the progress they are making toward solving frontier science questions with new models.
At @primateriacom, we are building chemical simulators that reflects reality, so we can run experiments for new discoveries entirely on a computer.
Are coding agents good enough to help us get there? To find out, we used experimental results to test their work on reengineering existing simulators.
Introducing Wavefunction bench: primateria.com/blog/wavefunc…
Emerson Hsieh retweeted
you can model biology with chemistry, chemistry with physics, and physics with math. so we're starting from building really good math solvers to create a model of reality.
can agents help us do it?
At @primateriacom, we are building chemical simulators that reflects reality, so we can run experiments for new discoveries entirely on a computer.
Are coding agents good enough to help us get there? To find out, we used experimental results to test their work on reengineering existing simulators.
Introducing Wavefunction bench: primateria.com/blog/wavefunc…
Emerson Hsieh retweeted
we need more evals for scientific discovery!
At @primateriacom, we are building chemical simulators that reflects reality, so we can run experiments for new discoveries entirely on a computer.
Are coding agents good enough to help us get there? To find out, we used experimental results to test their work on reengineering existing simulators.
Introducing Wavefunction bench: primateria.com/blog/wavefunc…
There is still quite a bit of work here, but we believe that getting virtual simulations to match experimental fidelity is one of the most valuable scientific problems available today.
If this is work that interests you, please join us at primateria.com/careers
Thank you to @josancamon19, @timgsereda, and @tax_cuts for your contributions!
And also thank you @AdamEFoster for your feedback on the post and for your work on Orbformer!
123 looks more predictable than 12 because three digits updates the bayesian posterior confidence that I'm typing sequential numbers instead of just twelve
Emerson Hsieh retweeted
Introducing edith-1, a decision model for online trace monitoring. We trained it to catch agent failures, reward hacking, and problems with tasks, graders and environments.
On our eval, it beat Sonnet-5.5 in Claude Code on balanced accuracy, at an estimated 1/274 of the cost.
Luofei is a brilliant and mission-driven engineer. Building a personal intelligence machine has been his dream since I met him more than ten years ago, and I’m glad we’re at the right time for his vision to come true. Congrats on the launch! 😊
Say hello to Oki Home, your Personal AI Computer.
We're building a future of limitless, personalized intelligence for every consumer, while keeping all your data in your hands.
Reserve our first batch, shipping mid-december! okihome.ai
Emerson Hsieh retweeted
Introducing pgrust v0.3: the bug-smashing release.
We evaluated pgrust v0.2 and v0.3 against the same held-out corpus: 164,000 test cases from 50 open-source projects.
pgrust v0.2 diverged from Postgres on 1,454 cases. pgrust v0.3 diverged on 11.
pgrust is 300x faster than Postgres for analytical workloads, and we're a drop-in replacement.
Held-out corpus included: @djangoproject, SQLAlchemy, Hibernate, @rails, and more.
@pgrustdb is now much more Postgres-compatible and reliable than before. @JasonSeibel and I don't recommend running pgrust in production (yet), but we are successfully running it ourselves internally.
- @AntithesisHQ and @workersdotio for simulation testing
- Detail.dev by @danlovesproofs for LLM-assisted code analysis
- Multiple home-built differential fuzzers
- Kani for formal verification
Our goal is for pgrust to be truly 100% compatible with Postgres.
There are still bugs. You should still run Postgres for any data you can't afford to lose.
But we want people trying pgrust on real workloads in non-critical environments. If you need Clickhouse performance queries in Postgres, are frustrated by the many gotchas in Postgres, or just geek out about databases and Rust, feel free to send me a DM as we would love to chat.
Emerson Hsieh retweeted
Primateria is led by two of the most ambitious, mission-driven founders in the industry.
Throughout the Primodium -> Primateria journey, they've developed leading-edge research from first principles while holding themselves to an exceptionally high bar: building a commercial enterprise capable of the largest possible positive impact.
I'm excited for what comes next!
Announcing Primateria, an AI-native scientific lab.
We’re starting with one of the hardest problems in quantum mechanics: the electronic Schrödinger equation.
Our first model tackles it in transition metals, a notoriously difficult regime.
Try it: app.primateria.com/
Emerson Hsieh retweeted
In 1929 Dirac said we already knew the equations for all of chemistry - they were just impossible to actually solve. Almost 100 years later, and we are getting close!
Announcing Primateria, an AI-native scientific lab.
We’re starting with one of the hardest problems in quantum mechanics: the electronic Schrödinger equation.
Our first model tackles it in transition metals, a notoriously difficult regime.
Try it: app.primateria.com/
Emerson Hsieh retweeted
a cool launch from the coolest brothers I know
Announcing Primateria, an AI-native scientific lab.
We’re starting with one of the hardest problems in quantum mechanics: the electronic Schrödinger equation.
Our first model tackles it in transition metals, a notoriously difficult regime.
Try it: app.primateria.com/
Emerson Hsieh retweeted
Announcing Primateria, an AI-native scientific lab.
We’re starting with one of the hardest problems in quantum mechanics: the electronic Schrödinger equation.
Our first model tackles it in transition metals, a notoriously difficult regime.
Try it: app.primateria.com/












