Jordan Smoller (@jorsmo) header
Jordan Smoller (@jorsmo) profile picture

Jordan Smoller

@jorsmo

Psychiatry, Genetics, Epidemiology, Precision Medicine. Author of The Other Side of Normal. 3% Neanderthal. Now on BlueSky https://nitter.cf/t.co/xHoXRBGKFr

 Harvard and MGH
smollerlab.org
Joined April 2009
  • Tweets6.1K
  • Following1.5K
  • Followers3.8K
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Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)Photo by Jordan Smoller (@jorsmo)
📢 Don't miss out!📢 🎟️Registration is now OPEN for our 3rd CSRP Conference 🎟️bit.ly/44lOFAY or go to our website to learn more: bit.ly/4vUfurZ @CAPESuicidePrev @YeatesConwell @zimmerman082
Image from Center for Suicide Research and Prevention (@the_CSRP)
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Jordan Smoller retweeted
Sarah Urbut (@tigerstatdoc) profile picture
Sarah Urbut
@tigerstatdocJul 15
One of my first consults as a cardiology fellow: a 34-year-old, textbook MI. A day earlier, no risk model would have flagged him for prevention. That paradox has driven my work ever since — our models miss how disease actually evolves, dynamically, on top of a genetic background. @Nature nature.com/articles/s41586-0…
Image from Sarah Urbut (@tigerstatdoc)
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Hope you'll join us for this free webinar on the important topic of grief and suicide loss.
Image from Jordan Smoller (@jorsmo)
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Congratulations to the amazing Mike Talkowski ⁦@TalkowskiLab⁩ on receiving the Scientific Achievement Award from ⁦@GeneticsSociety⁩ A visionary scientist and outstanding human!
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Happening this Wednesday, September 24th! The Predictive Models in Neuroimaging Workshop! Join us virtually from 10am-3:00pm ET! Students, fellows, interns, & trainees can register for 50% off! Seats are limited so register today at mghcme.org/Precision2025
Image from Center for Precision Psychiatry (@MGHPrecisionPsy)
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THIS WEEK! The 5th Annual Conference on Precision Psychiatry! Join virtually September 25-26 to hear from our exciting lineup of speakers & panelists! Students, fellows, interns, & trainees can register for FREE! Earn 8 CME credits! Register @ mghcme.org/precision2025
Image from Center for Precision Psychiatry (@MGHPrecisionPsy)
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“If we survive I will be somewhat surprised,” cnn.com/2025/07/08/health/na…
World’s premier cancer institute faces crippling cuts and chaos | CNN

World’s premier cancer institute faces crippling cuts and chaos | CNN

The Trump administration’s broadsides against scientific research have caused unprecedented upheaval at the National Cancer Institute, the storied federal government research hub that has spearheaded...

cnn.com
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Join us September 23rd for the Hands-on AI in Precision Psychiatry Workshop. 💻 Fully virtual 🕙 10:00am–3:30pm ET 🔗 Sign up: mghcme.org/Precision2025
Image from Center for Precision Psychiatry (@MGHPrecisionPsy)
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Hear from Keynote speaker Dr. Marion Leboyer at this year's 5th Annual Conference on Precision Psychiatry! Tune in virtually Sept 25–26, 2025! -FREE registration for students, fellows & trainees -Earn 8 CE credits Register: mghcme.org/Precision2025
Image from Center for Precision Psychiatry (@MGHPrecisionPsy)
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A must-read on the impact of defunding biomedical research and healthcare infrastructure nytimes.com/interactive/2025…
Opinion | How to Wreck the Nation’s Health, by the Numbers (Published 2025)

Opinion | How to Wreck the Nation’s Health, by the Numbers (Published 2025)

The administration's cuts to the Department of Health and Human Services are going to do irreparable harm to the nation’s health.

nytimes.com
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🆕📽️Last week's webinar is available now on YouTube! How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors youtu.be/TMCAikdy2dQ?si=Z8Rk… Thank you to everyone who joined & @cmoutierMD @lab_jobes @TonyPisani @katespeer1 @jorsmo @mk_nock @afspnational
How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors

How to Help a Loved One Struggling with Suicidal Thoughts and Behaviors

Recorded at the CSRP Webinar titled, “How to Help a Loved One Strug...

youtube.com
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How polygenic score effects vary by context and interacting contexts with Mihael Cudic @jd_tubbs Tian Ge Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute Genetic Risk medrxiv.org/content/10.1101/…
Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute...

Putting Polygenic Scores in Context: How Intersectional Factors Affect Relative and Absolute...

Background The clinical utility of polygenic scores (PGS) is known to vary when training and test samples differ in ancestry, with recent work suggesting that sociodemographic differences can also...

medrxiv.org
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🚨🧬 New preprint! We tested whether PGS predicted global functioning across psychiatric hospitalization among 5991 people with schizophrenia. medrxiv.org/content/10.1101/…
Polygenic Scores for Schizophrenia and Educational Attainment Predict Global Functioning Across...

Polygenic Scores for Schizophrenia and Educational Attainment Predict Global Functioning Across...

Question Is variation in global functioning among people with schizophrenia associated with genetic differences? Findings In this genetic association study of 5991 adults with schizophrenia and...

medrxiv.org
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Another breakthrough made possible by federal funding The result “is a triumph for the American peoples’ investment in biomedical research” Baby Is Healed With World’s First Personalized Gene-Editing Treatment nytimes.com/2025/05/15/healt…
Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Published 2025)

Baby Is Healed With World’s First Personalized Gene-Editing Treatment (Published 2025)

The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.

nytimes.com
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"The largest number of terminated grants was adminis- tered by the NIMH (n = 128) and the NIMHD (n = 77) (Table 1)." Characterization of Research Grant Terminations at the National Institutes of Health pubmed.ncbi.nlm.nih.gov/4033…
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"let’s be clear: It isn’t institutions that are being punished. It’s the researchers who are the future of science in this country" What am I supposed to say to this generation of young scientists? statnews.com/2025/05/07/us-s… via @statnews
What am I supposed to say to this generation of young scientists?

What am I supposed to say to this generation of young scientists?

Undermining the future of American science is not a path to accountability — it’s a path to decline.

statnews.com
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Devastating "The National Institutes of Health would take the largest cut in the Trump proposal, losing nearly $18 billion compared to the 2025 budget." Trump proposes billions in cuts to federal health agencies from NIH to CDC statnews.com/2025/05/02/skin… via @statnews
Trump proposes billions in cuts to federal health agencies from NIH to CDC

Trump proposes billions in cuts to federal health agencies from NIH to CDC

Trump proposed massive cuts to federal health agencies in his 2026 'skinny budget' request.

statnews.com
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another example of how research = hope nytimes.com/2025/04/27/healt… @ginakolata
Medicine Spares Cancer Patients From Grisly Surgeries and Harsh Therapies (Published 2025)

Medicine Spares Cancer Patients From Grisly Surgeries and Harsh Therapies (Published 2025)

For a limited group of cancer patients who have solid tumors in the stomach, rectum, esophagus and other organs, an immunotherapy trial offered stunning results.

nytimes.com
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Great piece from @Atul_Gawande newyorker.com/news/the-lede/…
The Cost of Defunding Harvard

The Cost of Defunding Harvard

If you or someone you love has cancer, cardiovascular disease, dementia, Parkinson’s disease, or diabetes, you have likely benefitted from the university’s federally funded discoveries in care and...

newyorker.com
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In a new study, researchers from @MGHPsychiatry used machine learning to enhance the accuracy of predicting suicide risk. The study was published in @JAMAPsych. Read more: jamanetwork.com/journals/jam… @drkatebentley @c3k @TaylorABurkePhD @jorsmo
Image from Mass General Brigham Research (@MGBResearchNews)
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