Open Science Education on Longevity. Non-profit & open-source platform to democratise and centralise information on Aging. Search for a longevity topic👇
Joined April 2021
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Longevity Wiki retweeted
this (@longevitywiki) is well-written and deserves many more eyes and scientists contributing!
en.longevitywiki.org/wiki/Lo…
Longevity Wiki retweeted
Our Aging Fly Cell Atlas is out. Do different cell types age at the same rate? No. Which cell types age faster? Fat, liver and muscle. Which cell types age slower? Neurons. Great collaboration with @StephenQuake @HenriJasper @mariabrbic @TzuChiaoLu
Longevity Wiki retweeted
🔥🔥🔥Our new ground breaking #preprint is out: ➡️Accurate aging clocks based on accumulating stochastic variation. Read now @researchsquare and 🧵below. Congrats to @Meyer_DH! @CGA_age @CECAD_ @UniCologne @UKKoeln researchsquare.com/article/r…
Longevity Wiki retweeted
Learned today that a nicotinamide riboside supplement maker (not Chromadex) is targeting authors of a recent paper suggesting possible increased cancer risk from NR. This is bad news for science 1/6
Longevity Wiki retweeted
A really big thanks from us all to you for all the great work you do in the longevity field 🙏
@Blagosklonny @mkaeberlein @KaeberleinTammi @kapahi_pankaj @RossPelton @KillenMd @robertlufkinmd @PeterAttiaMD @DrBradleyRosen1 @AtillaOzmumcu @AndreeaNRD
nitter.cf/KristerKauppi/status/1…
Longevity Wiki retweeted
Thank you to Prof. Kaeberlein (@mkaeberlein) for doing a podcast on my channel!
We discussed:
- The Dog Aging Project (@DogAgingProject)
- Intermittent Fasting
- Protein Intakes
- Rapamycin & mTOR
- Combination Therapies
- Metformin
- SGLT2i
- Creatine
youtu.be/y8pnyRsEoEI
Longevity Wiki retweeted
For those unfamiliar with both the potential benefits and risks of rapamycin: preprints.org/manuscript/202… - and hopefully a comprehensive new article on this subject coming out next year!
Longevity Wiki retweeted
Our recent work "A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis" made it to the Cover of @NatureAging August issue!
Volume 2 Issue 8, August 2022 - nature.com/nataging/volumes/…
Longevity Wiki retweeted
Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: [RCT]
academic.oup.com/biomedgeron…
⬇️ “age-associated declines” eg’s @ ~2-weeks
Longevity Wiki retweeted
Congratulations to the authors of this important research completed by @salkinstitute and @KAUST_News, including five outstanding scientists who have joined the Altos team. Remarkable work by all involved identifying this promising rejuvenation target science.org/doi/10.1126/scit…
Longevity Wiki retweeted
As billionaires race to fund anti-aging projects, a much-discussed trial goes overlooked statnews.com/2022/08/09/anti… via @MeganMolteni
Longevity Wiki retweeted
How much extra healthy longevity can lifestyle alone get you? Studies seem to suggest ~7 years. I'd guess up to 10. You absolutely should focus on this - it's well worth it and very doable. But without geroscience interventions, lifestyle alone will only get you so far
Longevity Wiki retweeted
Many have questioned whether some of these companies still work on aging.
I think many companies start by trying to understand aging, but once they realize how hard this is, they pivot to a low-hanging fruit, eg age-related disease.
This is why we still need blue skies research
Top 15 longevity companies in 2022 by $
Even excluding Altos Labs, the top 15 companies have 2x the median funding and 28% more total funding than in 2021.
Longevity biotech continues to grow 🚀
Full list of longevity companies:
whoswho.senescence.info/comp…
Longevity Wiki retweeted
We need good open wiki data and knowledge. Longevity field is made of shiny nonsense. GDF11, Telomeres, Senescent Cells, Epigenetic clocks, Transposons are not the issue. These are a marketing gimmick. When you get to shallow bottom, we know nothing. Yes I have citations backup.
Longevity Wiki retweeted
How An Anti-Inflammatory Diet Might Improve Your Health 🙌
"In a population study, scientists have found that consuming foods associated with a low Diet Inflammatory Index substantially lowers the risk of dementia..."
lifespan.io/news/anti-inflam…
Longevity Wiki retweeted
How Much Ginger Do You Consume? 🧐
"Gingerenone A, a component of ginger extract, is a natural senolytic that is potentially more powerful and less toxic than the combination of dasatinib and quercetin"
lifespan.io/news/ginger-extr…
Longevity Wiki retweeted
How Critical Do You Think CD38 Is? 🤔
"Significantly extended lifespan in male mice by inhibiting the enzyme CD38, which lowers NAD levels"
lifespan.io/news/new-candida…
Longevity Wiki retweeted
How Much Might This Help In The Fight Against Cancer? 🤔
"Chemotherapy has proven to be a valuable tool in treating cancers... but it has a big downside... it can also kill healthy cells... causing baldness; and... causing nausea."
medicalxpress.com/news/2022-…
Longevity Wiki retweeted
How Excited Are You About The Potential Of Calorie Restriction? 🧐
"Caloric restriction shapes the gut microbiome which can improve metabolic health and may induce a shift towards the naïve T and B cell compartment and, thus, delay immune senescence."
microbiomejournal.biomedcent…
Longevity Wiki retweeted
How Much Do You Know About The Potential Of Corylin? 🧐
"Corylin, which is derived from the Chinese herb Psoralea corylifolia, increases the lifespan of model organisms through well-known pathways of aging."
lifespan.io/news/corylin-sho…