Giovanni E Mann (@mann_ivel) profile picture

Giovanni E Mann

@mann_ivel

Prof. Vascular Physiology, King's College London (research: redox signaling; diabetes; cardiovascular; stroke; defining physiological normoxia) views are my own

 London, UK
kcl.ac.uk/lsm/research/divisions/cardio/about/people/manng.aspx
Joined November 2015
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Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)Photo by Giovanni E Mann (@mann_ivel)
Giovanni E Mann retweeted
Nature Metabolism (@NatMetabolism) profile picture
Nature Metabolism
@NatMetabolismOct 2
Maternal obesity imprints methylation marks in oocytes to drive intergenerational metabolic dysfunction dlvr.​it/TVl8W9
Image from Nature Metabolism (@NatMetabolism)
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Giovanni E Mann retweeted
The Physiological Society (@PhySoc) profile picture
The Physiological Society
@PhySocSep 30
🌍️ Physiology Week 2026 will be taking place 16-20 November this year worldwide! Want to take part but not sure how? Contact us at [email protected] and we’ll be able to help!
Image from The Physiological Society (@PhySoc)
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Giovanni E Mann retweeted
Lucid Scientific, Inc. (@lucidsci) profile picture
Lucid Scientific, Inc.
@lucidsciSep 28
Can stem cells be pre-adapted to the low-oxygen environment of a stroke-damaged brain? At #HypoxEULive, Eva Ferro (@bmanadas lab, @UnivdeCoimbra) showed how oxygen priming reshapes the proteome of UC-MSCs from 9 donors. Resipher tracked their respiration at 24, 48 and 72 h. #CellTherapy #Resipher
Image from Lucid Scientific, Inc. (@lucidsci)
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Giovanni E Mann retweeted
Lucid Scientific, Inc. (@lucidsci) profile picture
Lucid Scientific, Inc.
@lucidsciSep 17
That is a wrap on the @SFRBM North American Redox Symposium in Burlington. Thank you to everyone who stopped by to see respiration tracked continuously through an oxidative challenge and the recovery afterward. Missed us? Request a Virtual Demo: lucidsci.com #SfRBM #RedoxBiology #Mitochondria #Resipher
Image from Lucid Scientific, Inc. (@lucidsci)
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Giovanni E Mann retweeted
Nature Metabolism (@NatMetabolism) profile picture
Nature Metabolism
@NatMetabolismSep 15
Cysteine excess triggers a mitochondrial iron-dependent cell death dlvr.it/TVV53x
Cysteine excess triggers a mitochondrial iron-dependent cell death

Cysteine excess triggers a mitochondrial iron-dependent cell death

Nature Metabolism - Using a genome-wide CRISPR screen, the authors demonstrate that excess cysteine drives mitochondrial iron accumulation and iron–sulfur cluster failure, triggering a...

nature.com
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Giovanni E Mann retweeted
The Physiological Society (@PhySoc) profile picture
The Physiological Society
@PhySocAug 28
Discover the physiological factors that drive sporting success 🏃‍➡️ Join us for the livestream of the GL Brown Annual Public Prize Lecture presented by Professor Andrew Jones. 📆 09:25 BST, Tuesday 25 August Full details on how to watch it ⬇️ buff.ly/vmJCVic
Recent Advances in Nutritional Physiology: A Muscle-centric Perspective

Recent Advances in Nutritional Physiology: A Muscle-centric Perspective

Explore recent advances in nutritional physiology as they pertain to skeletal muscle tissue. Find out more about the two-day meeting.

physoc.org
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Giovanni E Mann retweeted
The Physiological Society (@PhySoc) profile picture
The Physiological Society
@PhySocAug 27
🎉 Congratulations to the early career researcher competition winners! The awards were announced at our #NutritionalPhysiology meeting, which took place on 25-26 August. Presenting the awardees for short talks and flash talks:
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🧾 ورقة علمية مفيدة جدًا للمبتدئين في مجال البحث العلمي! تشرح بشكل مبسط ومنظم الخطوات الأساسية لكتابة ورقة علمية من الفكرة وحتى النشر، بما يشمل كتابة أقسام البحث المختلفة، اختيار المجلة المناسبة، والتعامل مع عملية المراجعة العلمية. ننصح بقراءتها لكل من يرغب في تطوير مهاراته البحثية أو يستعد لكتابة بحثه الأول 📚✨ 🔗 رابط المقال: bit.ly/4fJEsF1
Image from Researchable | ريسيرشيبل (@Researchable_SA)
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Giovanni E Mann retweeted
Physiological Reviews (@physiolrev) profile picture
Physiological Reviews@physiolrevAug 27
🔓Open access: Mechanisms of transcranial magnetic brain stimulation Marcello Massimini et al. ow.ly/xaIT50ZG8GK #animalmodels #electroencephalography
Image from Physiological Reviews (@physiolrev)
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Giovanni E Mann retweeted
Europe-SFRR (@SFRR_Europe) profile picture
Europe-SFRR@SFRR_EuropeAug 26
📣 NEW SEASON, NEW WEBINARS! 🎉 The 5th SFRR-E ECR webinar series is here! 🔬🌍 Check the lineup, save the dates & join us for cutting-edge redox research from ECRs worldwide! 👉 Webinars: tinyurl.com/SFRREWebinar 🔗 Follow us: linktr.ee/SFRRE #SFRRE #ECR #Redox
Image from Europe-SFRR (@SFRR_Europe)
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Review Article ‘Mechanistic Insights into Selenium Nanoparticles: Comparative Effects in Plant and Animal Systems’ Zhang’s et al., Free Radic Biol Med online 22 Sep 2026 (sciencedirect.com/science/ar…) @SFRR_Europe @SFRBM @SFRRAustralasia @Sciencedirect
Image from Giovanni E Mann (@mann_ivel)
Image from Giovanni E Mann (@mann_ivel)
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Giovanni E Mann retweeted
Lucid Scientific, Inc. (@lucidsci) profile picture
Lucid Scientific, Inc.
@lucidsciAug 20
Three days, one live experiment, and a lot of good questions. Last week we hosted Shinsaku, Yu, and Fumi from CosmoBio and BMBio at our Atlanta headquarters for Resipher distributor training. We ran a live experiment across the entire visit, so by Wednesday everyone was looking at real oxygen consumption data that had been collected since Monday morning. Hard to explain continuous respiration in a slide. Much easier to just point at the plate. Thank you to the @CosmoBio_JPN and BMBio team for making the trip and for the energy you brought to every session. Japan is a serious market for mitochondrial and metabolic research and I am glad we are entering it with partners who care this much about getting the science right.
Image from Lucid Scientific, Inc. (@lucidsci)
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Giovanni E Mann retweeted
Cell Metabolism (@Cell_Metabolism) profile picture
Cell Metabolism@Cell_MetabolismAug 6
Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotective effects dlvr.it/TTth3Z
Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotec...

Oral GLP-1 receptor agonist promotes astrocyte-neuron lactate and lipid transfer with neuroprotec...

Du et al. demonstrate that the oral and brain-penetrant GLP-1RA OHP2 activates GLP-1R on astrocytes to increase aerobic glycolysis. The resulting lactate increases H3K9la levels in neurons and...

cell.com
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Giovanni E Mann retweeted
Cell Metabolism (@Cell_Metabolism) profile picture
Cell Metabolism@Cell_MetabolismAug 6
Reactive species as regulators of immune cell metabolism, tolerance, and autoimmunity dlvr.it/TTv3nQ
Reactive species as regulators of immune cell metabolism, tolerance, and autoimmunity

Reactive species as regulators of immune cell metabolism, tolerance, and autoimmunity

Reactive species, including reactive oxygen species, act as both essential signals and drivers of pathology in immune cells. Kobayashi and Brenner review how redox chemistry shapes immune cell...

cell.com
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Giovanni E Mann retweeted
The Physiological Society (@PhySoc) profile picture
The Physiological Society
@PhySocAug 7
It all started in a London townhouse on 31 March 1876, at the home of Sir John Scott Burdon-Sanderson... For our 150th anniversary, members share their stories about their life, work, & consider the next chapter for physiology. Browse the collection 🔗 buff.ly/G9hD6yZ
Image from The Physiological Society (@PhySoc)
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How can magnetic pulses change activity inside the brain? A new review in @physiolrev explains how this noninvasive technique activates nerve fibers and brain networks—insights that could lead to more targeted treatments: ow.ly/W2R950Zus6G #ArticlesInPress 📷: @istock
Image from American Physiological Society (@APSPhysiology)
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Giovanni E Mann retweeted
Giovanni E Mann (@mann_ivel) profile picture
Giovanni E Mann@mann_ivelAug 7
Review article ‘XANTHINE OXIDOREDUCTASE IN DIGESTIVE DISEASES: A CONTEXT-DEPENDENT REDOX SWITCH LINKING INFLAMMATION, METABOLISM AND CARCINOGENESIS’ Battelli et al., Free Radic Biol Med 4 Aug 2026 (sciencedirect.com/science/ar…) @SFRRAustralasia @SFRR_Europe @SFRBM @Sciencedirect
Image from Giovanni E Mann (@mann_ivel)
Image from Giovanni E Mann (@mann_ivel)
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Review article ‘XANTHINE OXIDOREDUCTASE IN DIGESTIVE DISEASES: A CONTEXT-DEPENDENT REDOX SWITCH LINKING INFLAMMATION, METABOLISM AND CARCINOGENESIS’ Battelli et al., Free Radic Biol Med 4 Aug 2026 (sciencedirect.com/science/ar…) @SFRRAustralasia @SFRR_Europe @SFRBM @Sciencedirect
Image from Giovanni E Mann (@mann_ivel)
Image from Giovanni E Mann (@mann_ivel)
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Giovanni E Mann retweeted
Physiological Reviews (@physiolrev) profile picture
Physiological Reviews@physiolrevJul 29
Dr. Sadis Matalon interviews author Dr. Sophia Karagiannis about antibody-drug conjugates, "magic bullets” that kill cancer cells with minimal damage to healthy tissue. What are the obstacles to manufacturing ADCs? 🎧 @physiolrev Podcast ow.ly/ycJw50Zuvnb
Image from Physiological Reviews (@physiolrev)
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Giovanni E Mann retweeted
Lucid Scientific, Inc. (@lucidsci) profile picture
Lucid Scientific, Inc.
@lucidsciJul 29
From round to square, V-shaped to conical, Resipher handles it all. Our innovative design ensures precise and reliable results when measuring live, long-term bioenergetics – no matter the well shape. Learn more about Resipher's capabilities on our website >>> lucidsci.com/resipher #bioenergetics #96WellPlate #cellculture #Resipher
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