Gerontologist, senescence aficionado and associate professor @ European Research Institute for the Biology of Ageing (ERIBA). Opinions are mine
Groningen, The Netherlands
Joined December 2013
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Marco Demaria retweeted
Online now! Cerrato et al propose a consensus roadmap towards precision senescence medicine, emerging from the SENESCENCE2030 meeting in Coimbra, Portugal earlier this year @marc_dema nature.com/articles/s43587-0…
Marco Demaria retweeted
🧬 Senescent cells accumulate as we age, can we understand them for better therapies?
@marc_dema will explore how understanding senescence could help develop new approaches to healthier ageing at #BSRA2026
🗓️ 9–11 Sept
📍 Keble College, Oxford
🔗bsra.org.uk/events/75th-annu…
Marco Demaria retweeted
Online now!✨Wang et al report a role for CDK4/6 in regulating not only cell cycle progression but also the SASP, via retinoic acid signaling and NFkB. Targeting this pathway reduces inflammation and improves function in aged mice @Marc_dema nature.com/articles/s43587-0…
Marco Demaria retweeted
We are pleased to announce the Senotherapeutics Biomarker Consortium (SBC) Inaugural Summit, taking place on December 7, 2026 at the Clark Center Auditorium, Stanford University.
Registration is now open: luma.com/k0wu72e0
#PhaedonInstitute #SBC2026 #Senescence #Longevity
Marco Demaria retweeted
Thank you, @marc_dema (@umcg) for a great #CeMMinar on heterogeneity in cellular #senescence! He shared how senescent cells can both aid tissue repair & drive aging & dysfunction, & how targeting them could support healthy #aging. Thanks to hosts @rooij_laura & André Rendeiro!
Marco Demaria retweeted
Removing p16⁺ senescent cells rejuvenates female liver profiles—boosting mitochondrial function and reducing inflammation, mimicking effects of calorie restriction, #rapamycin, and #acarbose, a new study finds. #senescence
By Yao Lin, @marc_dema, et al.
advanced.onlinelibrary.wiley…
Marco Demaria retweeted
#Comment on the accelerated aging phenotype in cancer survivors by Marc Demaria @marc_dema
Read it here: nature.com/articles/s41568-0…
Marco Demaria retweeted
We were proud to sponsor a poster prize at the ICSA Conference & Senotherapeutics Summit in Rome, co-organized by our EIC @marc_dema.
🎉 Congrats to Cheng Chen (Pasteur Institute, Paris), prize winner for her work on senescent FAPs in muscle regeneration!
#ICSA2025 #Aging
ALT 10th Annual ICSA Conference & 2nd Phaedon SenoTherapeutics Summit
ALT 10th Annual ICSA Conference & 2nd Phaedon SenoTherapeutics Summit
Marco Demaria retweeted
Aging-US supports a milestone event for the global senescence & aging research community. @marc_dema
🗓️ September 16-19, Rome:
🔹10th Annual ICSA Conference
🔹2nd Phaedon Senotherapeutics Summit
Learn more and register ⬇️
aging-us.com/news-room/aging…
#ICSA2025 #Aging #Longevity
ALT 10th Annual ICSA Conference & 2nd Phaedon SenoTherapeutics Summit
Super excited to invite you to #ICSA2025 in Rome– September 16-19!
This will be a special edition—celebrating 10 years of ICSA, and joining forces with the Phaedon Institute for a full day dedicated to senotherapeutics! icsa2025rome.com/en/summary/…
#Senescence #LongevityScience #Aging
Can aging biology reshape healthcare?
In my latest editorial for @AgingJrnl , I argue it's time to shift from reactive disease treatment to proactive, biology-driven strategies that extend healthspan.
aging-us.com/article/206262/…
#AgingResearch #Healthspan #Geroscience #Longevity
Marco Demaria retweeted
"I am committed to advancing the journal’s mission by promoting rigorous science and encouraging interdisciplinary dialogue that bridges basic biology with clinical relevance." - @marc_dema
Read the full message from our new Editor-in-Chief:
🔗 aging-us.com/statement-from-…
#aging
ALT STATEMENT FROM OUR EDITOR-IN-CHIEF
Marco Demaria retweeted
📢#CallforPapers: Aging (Aging-US) invites #submissions on cellular #senescence - its mechanisms, functions & clinical applications - in memory of Dr. Judith Campisi. @marc_dema
📅Deadline: January 15, 2026
🔗Submission Details:
aging-us.com/judith-campisi-…
#AgingResearch #oa
ALT Call for Papers: Commemorative Collection Honoring Dr. Judith Campisi
Marco Demaria retweeted
Our Longevity & Aging Series hosted by @EvgenyGalimov is a Finalist for a 2025 EPIC Award in the Video/Film category! Grateful to be recognized alongside so many talented professionals. #ScholarlyPublishing
@marc_dema @elevatemginc
sspnet.org/community/news/so…
#Aging #Longevity
Marco Demaria retweeted
📢#CallforPapers: Aging (Aging-US) is honoring @Blagosklonny with a special #collection.
Submit your #research, reviews and perspectives on mTOR, rapamycin, #aging, cancer & more.
📅Deadline: December 1, 2025
🔗Submission Details:
aging-us.com/mikhail-blagosk…
#agingresearch
ALT Call for Papers: Commemorative Collection Honoring Dr. Mikhail Blagosklonny
Check out my recent comment lnkd.in/e7KBsdSB on the accelerated aging phenotype in cancer survivors. With increasing survivorship, understanding & addressing this issue is critical to improve quality of life. Free full access: rdcu.be/ebwhr #Longevity #Aging
At aging-us.com/ we're seeking original research, reviews & perspectives on aging & age-related diseases, including:
- Biology of aging
- Translational & clinical research
- Epidemiology & multi-morbidity
Submit your best work!
#AgingResearch #Longevity #AgingUS
Excited to share our latest doi.org/10.1038/s44318-025-0… revealing a novel approach to enhance the efficacy of CDK4/6 inhibitors in breast cancer treatment based on targeting aberrant lysosomes #BreastCancer #Senescence #CDK4_6Inhibitors #EMBOJournal #Senolytics #Aging #Longevity
We show that:
CDK4/6i induces a senescent-like state in breast cancer cells but these cells resist common senolytics;
Lysosomal alterations make them vulnerable to lysosomotropic agents (LLOMe, salinomycin);
Sequential treatment reduces tumor growth in HR+ & some TNBC models