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Latest trending medical research, guidelines and news

Joined July 2020
Medical Mnemonics is FREE to download: 38 chapters, 7 parts and 654 searchable pages, with a clickable index and PDF bookmarks. Get the book and explore more clinical learning at updatesinmedicine.com/books
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🏃‍♂️ Exercise as Medicine! The 2026 ACC Scientific Statement highlights practical exercise prescriptions for cardiovascular prevention and management, including CAD, heart failure and hypertension. 📖 Read the full clinical article at UpdatesInMedicine.com
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KDIGO 2027 CKD update: proposed changes to SGLT2 inhibitors, nsMRAs and GLP-1-based therapies, alongside established CKD treatment. October 2026 public review draft. Read the summary: UpdatesInMedicine.com
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Download the latest medical guidelines—all in one place. Visit UpdatesInMedicine.com
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🧠 Light became a switch for the brain. The 2026 Nobel Prize in Physiology or Medicine honours Karl Deisseroth, Peter Hegemann and Georg Nagel for discoveries concerning light-gated ion channels and optogenetics.
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Retatrutide, a GIP–GLP-1–glucagon triple agonist, delivered up to 25% mean weight reduction at 80 weeks in TRIUMPH-1, with additional improvements in knee osteoarthritis pain and obstructive sleep apnoea. Read the full Research in Practice article at UpdatesInMedicine.com
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🚀 UpdatesInMedicine.com is now live! A new clinical update hub created for medical professionals. • Latest clinical guidelines • Important new research • Practical clinical reviews • Conferences, webinars & professional opportunities From evidence to everyday practice.
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2026 obesity pharmacotherapy: treatment is increasingly guided by clinical goals and obesity-related comorbidities—not weight loss alone. This update covers targets, drug selection, treatment intensification, follow-up, and muscle preservation.
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Iron deficiency diagnosis in 2026: • Ferritin ≤20 ng/mL: children 9 mo–4 y • ≤30 ng/mL: most adults • ≤50 ng/mL: selected higher-risk patients • In inflammation: use ferritin + TSAT; consider TSAT <20% or ferritin <100 ng/mL Normal Hb/MCV does not exclude iron deficiency
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Sodium bicarbonate corrected acidemia, but did not reduce 30-day major adverse kidney events in critically ill patients with metabolic acidosis on vasopressors. SODa-BIC Trial | NEJM 2026
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Glucose- Centric Glycemic Control Algorithm
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Comorbidity-Centric Type 2 Diabetes Treatment Algorithm
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Prediabetes is a chance to intervene early. The 2026 AACE algorithm emphasizes lifestyle, cardiometabolic risk reduction, and 7–10% weight loss in those with overweight/obesity to help prevent or delay T2D. Ref: Samson SL, et al. Endocrine Practice. 2026;32:473–518.
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Diagnosis, severity assessment and the right treatment remain central to malaria care in 2026. Key updates from the WHO Guidelines for Malaria — 10 September 2026.
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Cardiogenic Shock: 2026 definition
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Top 3 medical studies from August 2026 🔬 💊 STAREE: Statins ↓ CV events by 30% in adults ≥70 🫀 TARGET-CTCA: Routine CTCA showed no outcome benefit after MI was ruled out 💉 REIMAGINE 1: CagriSema delivered major HbA1c + weight reductions
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Met-HeFT found no significant cardiovascular benefit with metformin in HFrEF. Metformin remained safe and effective for glucose lowering, but did not reduce major cardiovascular events versus placebo.
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2026 definition of cardiogenic shock
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The 2026 ESC Heart Failure Guidelines bring major practice updates — from a new EF classification to faster treatment optimization, broader foundational therapy, and obesity-targeted care.
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The 2026 AHA/ASA stroke rehabilitation guideline reinforces a simple message: recovery is long-term, multidisciplinary, and focused on returning patients to life—not just discharge.
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