Toronto-based Psychiatrist & Neuroscientist @CAMHnews, Professor @UofT, President @ccnp_ca. #Pharmacogenetics #PrecisionMedicine Web: https://nitter.cf/t.co/YnLO3SEqdP (He/Him)
Toronto/tkaronto, ON
Joined October 2013
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Have you finished your psychiatry residency and are interested in specialized clinical training, contributing to exciting research projects, and receiving an accredited certificate of @uoftmedicine? 🎓
Then check out our current fellowship opportunities:
psychiatry.utoronto.ca/avail…
If you reside in the GTA/Durham region, feel significantly depressed, and are looking for treatment, please contact our team at: [email protected]
Daniel J. Mueller 🧠🔬 retweeted
This meta-analysis by Lauri Tuominen, Synthia Guimon et al. found widespread reductions in muscarinic and nicotinic receptors in schizophrenia, confirmed by neuroimaging and post-mortem studies. nature.com/articles/s41380-0…
Daniel J. Mueller 🧠🔬 retweeted
The Royal Ottawa Mental Health Centre welcomes Dr. Benoit Mulsant as the incoming chief of staff. A leader in psychiatry and digital health, he brings decades of experience to guide The Royal’s strategic transformation. theroyal.ca/news/dr-benoit-m…
Do plasma levels of psychotropic medications (plus their metabolites) matter for response and side effects?
Yes, they do.
Do pharmacogenetic (PGx) tests of CYP enzymes allow to predict plasma levels/metabolites?
Yes, they do.
Do PGx tests allow to predict (and explain past) response and side effects?
Yes, they do.
It's a simple equation! 🙂
Avoid wasting too much time with trial and error approaches.
#PsychUpdate25 – at Chicago, IL
#ACNP2024 - As usual, great science, inspiration, networking, and friendship!
Routine or in selcted cases, buy: PGx testing can save lives.
Thank you for sharing, @lena_pl
Will routine pharmacogenetic testing help us get better outcomes with antipsychotic prescription?
CYP2D6 and CYP2C19 ultrarapid metabolisms are associated with suicide ... sciencedirect.com/science/ar…
Coming up next - A practical guideline on pharmacogenetics unser consideration of population diversities:
#WCP24 – at Benito Juárez, Distrito Federal
...zooming in, @WPA_Psychiatry #WPA2024 Conference.
Wonderful clinical-research fellows opportunities at the @UofTPsych.
Everyone who has completed their residency is welcomed to apply.
More info: psychiatry.utoronto.ca/avail…
Questions? Fell free to DM! – at Benito Juárez, Distrito Federal
Inauguration of the first "Pharmacogenomics Interest Group (PIG)" meeting at the #WCPG2024
Many attendants joined; great to see so much interest in translational research, aimed to improve treatment for the individual patient.
Main goals of the "PIG":
- Networking to promote collaborative discoveries and liaising with the @pgrnhub psychiatric PGx interest group
- Promote implementation of PGx testing where evidence is strong (see @cpicpgx recommendations)
- Propose / join ongoing statements and updated review articles with @ISPGnet members on PGx in psychiatry
- Enhance and provide solid mentorship (both, clinical and research)
Interested to learn more about "PIG" 🐷? Please feel free to DM! – at Central Region, Singapore
Daniel J. Mueller 🧠🔬 retweeted
Ready for my #WCPG2024 poster on the AMBER project on causal mechanisms for antidepressants. We are running #pharmacogenomic GWAS studies for antidepressant response. Have studies? Have ideas? Talk to me
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Daniel J. Mueller 🧠🔬 retweeted
@mueller_dj kicking off the @ccnp_ca #CCNP2024 meeting in Calgary! An exciting program bringing together the best of basic, translational and clinical neuropsychopharmacology research in Canada!
You know it's the Annual Medical Staff Association dinner, when the staff gets spoiled with excellent food, engages in stellar conversations, *plus* enjoy this entertaining 'silly award' ceremomy, moderated by the unique Dr. Sara Colman! @CAMHnews – at Toronto, Ontario
Daniel J. Mueller 🧠🔬 retweeted
#Pharmacogenetic Variants and Plasma Concentrations of Antiseizure Drugs
"#CYP2C9 and #CYP2C19 genotypes encoding low enzymatic capacity were associated with a clinically relevant increase in #phenytoin plasma concentrations"
jamanetwork.com/journals/jam…
Daniel J. Mueller 🧠🔬 retweeted
🚨Open #postdoc position!
Join me and @Lundberg_lab at @karolinskainst @StratNeuro on a exciting collaborative project to study the molecular mechanisms behind the antidepressant effects of psychedelic compounds.
Apply here: ki.varbi.com/what:job/jobID:…
Please RT 🙌
Grateful for this @CIHR_IRSC Award to study genomic/pharmacogenomic factors contributing risk for difficult-to-treat (or treatment-resistant) major depressive disorder (MDD).
Study participants @CAMHnews with MDD will obtain evidence-based, state-of-the-art pharmacogenetic testing to rule out drug metabolism 'abnormalities' as they are followed up in a measurement-based care program.
This elaborated strategy will provide the best possible care and advance the transition into a new era of #PrecisionMedicine for individuals affected with MDD.
CAMH is proud to announce that we have received award funding as part of the CIHR (@CIHR_IRSC) Project Grant Spring 2024 competition, for a total of $4,686,177!
🎉Congratulations to our 7 grant awardees!
Highlight of the day?
Running into @RajjiTarek while shopping on Bloor Street and testing dress shirts together - on sale! 😄 #bargain #winwin – at Toronto, Ontario
