CEO @Ligandal 🧬: Tissue-specific targeting with AI + peptides (LigandForge). On a mission to enable precision personalized predictive medicine. Forbes 30U30.
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Joined March 2016
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You can design the next Ozempic for free on challenge.ligandai.com and get your designs submitted for wet lab validation via the @adaptyvbio x @AnthropicAI @proteinbase competition.
This will give a new meaning to mouthing off at someone
We’ve raised $1.3M from YC & Afore Capital so you never have to type or speak again.
Typing is slow. Talking into your computer is awkward. Subvocal fixes both
Our glasses give you the speed of speech without you making a sound or touching a keyboard.
It tracks your internal speech muscles with non-contact sensing and decodes silent, almost invisible mouthing into text at more than 200 words/min.
Pre-orders are now live at:
subvocal.co/preorder?utm_sou…
We’ve also launched a new classifier that predicts signaling state of GPCRs based on folded structures. Get more than a binder - this competition will measure signaling and activity of the GLP1R.
Live and free to try on challenge.ligandai.com
We are giving away 1 MILLION LigandForge designs as part of the Adaptyv Proteinbase + Anthropic protein design competition.
challenge.ligandai.com
Love this competition, but @AnthropicAI, are y’all aware that your models give [bio] classifier rejections to users trying to run your models for your own competition?
The only way we’ve been able to even query through this is with open models and @OpenAI
Announcing Challenge 2 of the Anthropic x Adaptyv Protein Design Competition!
Humira, the best-selling drug ever, blocks TNF-α, an inflammation marker protein that’s overexpressed in rheumatoid arthritis and Crohn’s disease. In this challenge, the goal is to make a better binder for TNF-α that also releases selectively at pH 6.0 in the endosome of cells to improve drug half-life.
The protein must also bind both human and mouse TNF-α, making it easier to test the same design in preclinical models.
The community will get to vote on which targets we should go after!
openlabs.bio.xyz/post/4e3c96… #openlabs
1.7 billion tokens processed (10.5M output) in 24h on a single RTX PRO 6000. Local intelligence has reached a point of being an actual production flow, not a toy. Opus 4.6 Max level intelligence, with additional intelligence served by Opus 5.5/5 & GPT Astra & local as workhorse.
