A consulting, collaborative organisation focussed on secondary uses for existing drugs, or drug repurposing. Four clinical stage development projects
Cambridge, UK
Joined February 2011
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Do new medicinal products need commercial exclusivity based on patent(s)? Conventional wisdom is 'yes', but for a recent new repurposed product for a rare disease, commercial exclusivity is actually derived mainly from the orphan designation, not patents. drugrepurposing.info/2022/09…
Natural Language Processing capability added to DrugRepurposingOnline - mailchi.mp/af0a87eb96f5/natu…, sign up for AI capabilities added to human expertise in drug repurposing. A true first.
Various new 'pull' incentives have been proposed by FDA to deal with the emerging antibiotic resistance crisis. In a new blog post, I ask if there are issues here with relevance for drug repurposing R&D? numedicus.co.uk/blog/what-yo…
Chem_ID 165 (drugrepurposing.info) could be a good treatment for preventing weight loss. #drugrepurposing #drugrepositioning #drugrescue
David Cavalla retweeted
An actual minister said this. Can we read this again? A member of govt admits Brexit's a fantasy they can't deliver. What. Are. We. Doing?
Not the first time that this old drug has shown promise in AD, but getting the money to follow is difficult!
Pilot CT for metformin improves cognition in Alzheimer disease drugrepurposing.info/index_t… #drugrepurposing #drugrepositioning #drugrescue
Clinical benefit of PPAR gamma agonist adjunctively in Schizophrenia drugrepurposing.info/index_t… #drugrepurposing #drugrepositioning #drugrescue
OBR figures show #Brexit will cost UK £300m a week (AFTER reduction in EU contribs), in ADDITION to £50bn Brexit divorce bill. #StopBrexit nitter.cf/ChukaUmunna/status/910…
Boris said Brexit would reclaim £350m a week, in reality it will cost us £300m a week. Per year, Vote Leave's figures were out by £33.8bn. nitter.cf/georgeeaton/status/910…
Pharmacological in vivo evidence harmine Glutamate transporter activator GLT-1 drugrepurposing.info/index_t… #drugrepurposing #drugrepositioning
Pharmacological in vivo evidence for antifibrotic effect of celiprolol drugrepurposing.info/index_t… #drugrepurposing #drugrepositioning
Pharmacological in vitro and in vivo evidence for Epo agonist in Hearing loss drugrepurposing.info/index_t… #drugrepurposing #drugrepositioning
Congratulations! There is one from me too. nitter.cf/hmpharmacon/status/908…
Solution: reimbursement price sh'd depend on indication and restrict generic competition for repurposed use. Simple. amazon.com/Off-label-Prescri…
#drugrepurposing hindered by off label generic use: no commercial model for most opportunities
FDA want to cut drug development costs: #drugrepurposing can help with that but need 2 change reimbursement model fiercebiotech.com/biotech/fd…
David Cavalla retweeted
Asthma drugs (β2AR agonists) may reduce #Parkinson’s risk via regulation of α-synuclein
cen.acs.org/articles/95/i35/…
science.sciencemag.org/conte…
Both @theresa_may and @UKLabour set 2 keep current relationship w EU until 2021, & prob beyond. #Brexit 2 difficult! bloomberg.com/view/articles/…
David Cavalla retweeted
New data: It was the Remain vote that drove Labour's surge during GE2017 pscp.tv/w/bFA9DTFtTUVQdllZZE…
