#KidneyDoctor #Researcher Member of @goKDIGO ExCom Member @SLANH #AKI committee Views do not represent those of my employer #NephroRunner #StopAKI
Joined March 2015
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Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
#ASNCJASN: Only 24% of older adults with advanced CKD accurately perceived their kidney failure risk. Fatalism, caregiver burnout, and knowledge gaps remained key barriers, highlighting the need for better risk communication. kidney.pub/CJASN1220
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
There is still time to share your feedback! The focused update of the KDIGO 2027 CKD Guideline is available for public review through November 4, 2026.
Visit the KDIGO CKD Guideline website to download the draft and share your comments via the feedback survey: kdigo.org/guidelines/ckd-evaโฆ
The focused update addresses new evidence since publication of the KDIGO 2024 CKD Guideline on SGLT2 inhibitors, GLP-1-based therapies, and nsMRAs in people with CKD, excluding those receiving dialysis or who have received a kidney transplant.
ALT KDIGO 2027 CKD Guideline Public Review Draft
๐ ๐ from Vietnam ๐ป๐ณ supports the Renal Angina Index for early prediction of severe AKI in critically ill ๐ง๐ผ.
In 314 patients, RAI โฅ8 showed 78.6% sensitivity and 70.5% specificity, with 7.4-fold higher odds of severe AKI.
#AKI #PedsNephrology
๐ link.springer.com/article/10โฆ
A multicenter study evaluated ML to predict KRT or in-๐ฅ death in critically ill patients with rhabdomyolysis.
External validation showed good discrimination (AUROC 0.89), outperforming McMahon score.
Findings support further prospective validation before clinical use.
๐ฌ Beyond creatinine: Rethinking kidney recovery after AKI
Emerging biomarkers may reveal persistent injury, inflammation, adaptive repair & fibrosisโoffering new insights into long-term kidney outcomes.
Is it time to redefine AKI recovery?
๐ ovid.com/jnls/co-nephrolhypeโฆ
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
๐ก #KidneyWk 2026 offered a valuable opportunity for ERA to strengthen international collaborations and explore new ways to advance nephrology worldwide.
๐ ERA leadership held fruitful meetings with the Japanese Society of Nephrology (JSN), KDIGO, and the Latin American Society of Nephrology and Hypertension (SLANH), reaffirming a shared commitment to scientific exchange, education and international cooperation.
โ๏ธ A key milestone was the signing of a new Memorandum of Understanding with JSN, marking an important step forward in our partnership.
๐ค These exchanges highlight the importance of working across borders, sharing knowledge and strengthening connections within the global nephrology community.
@jsnorjp
@goKDIGO
@SLANH_
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
#ASNCJASN: A small, early eGFR dip may be a sign treatment is working. In MIRO-CKD, balcinrenone plus dapagliflozin produced modest, reversible eGFR reductions associated with greater lowering of blood pressure and albuminuria, with no increase in serious safety events. kidney.pub/CJASN1202
๐ซ Empagliflozin in ADPKD: A pilot RCT (JASN; n=50) showed good tolerability and an early eGFR dip followed by stabilization, but greater kidney volume increase vs placebo.
๐ฌ Larger trials needed.
๐ ovid.com/jnls/jasn/fulltext/โฆ
๐ Drug dosing in post-dilution HDF: Are standard HD doses appropriate? A review highlights the impact of drug properties, convection volume, & post-dialysis rebound on drug clearance. Individualized dosing & therapeutic drug monitoring are essential.
๐ journals.lww.com/cjasn/fulltโฆ
Promising advances in kidney transplant desensitization!
A phase 1 study reports that dual CD19/BCMA CAR-T therapy induced profound but transient B-cell depletion, โฌ๏ธHLA sensitization, & enabled kidney transplantation in 2 highly sensitized patients
๐DOI: 10.1056/NEJMoa2513428
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
Resistant hypertension remains a major global challenge. Better BP monitoring, optimized multidrug therapy, and emerging precision treatments are improving how we diagnose and manage this high-risk condition. #Review in #ASNCJASN. kidney.pub/CJASN1266
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
Congratulations to Robert G. Narins Award recipient Ravindra L. Mehta, MBBS, MD, DM, FASN. His work has helped shape modern acute kidney injury care through advances in AKI classification, fluid management, and continuous kidney replacement therapy. kidney.pub/KN1810-24 #ASNKidneyNews
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
#kidneywk Day 3 of simultaneous publications covered by #nephjc
Until the next time ๐
โ๏ธ@CristinaDeReins @dra_miliflores @DrAkshayaJ @hswapnil @brian_rifkin @kidney_boy
nephjc.com/news/denver-day3
Rolando Claure, MD, FASN, FISN ๐ง๐ด retweeted
Late Breaking Clinical Trial #LBCT #KidneyWk: Empagliflozin at 25mg once daily was well-tolerated by ADPKD patients from @asnpublications
#Nephpearls
๐ Empagliflozin induced an expected acute decline in eGFR by 1 month, followed by stable eGFR.
๐ However, those treated with empagliflozin had a greater increase in kidney volume.
#KidneyWk ๐๐ปRethinking post-AKI care!
๐ฅ COPE-AKI trial: Can multidisciplinary care improve recovery after severe AKI?
๐ฉโโ๏ธ Nurse navigator + pharmacist + nephrologist + remote monitoring
๐ฏ: hospital-free days at 90 days.
Kidney recovery needs team-based care beyond discharge!
#KidneyWk 2026 | Post-AKI care: One size does NOT fit all!
KAMPS provides a framework:
๐ฉบ Kidney function
๐ข Advocacy
๐ Medications
๐ฉธ Pressure
โ ๏ธ Sick-day rules
๐ก Recovery care must be individualized by AKI etiology, comorbidities & medication needs.
#KidneyWk 2026 | Closing the post-AKI care gap
๐ AKI documentation at discharge improved from 22% to 92% with bundled intervention.
โ ๏ธ Yet fewer than 25% receive๐ซ function testing within 90 days.
AKI recovery requires structured follow-up, better โน๏ธ & multidisciplinary care!
#KidneyWk 2026 | Moving from AKI recognition to prevention!
๐ Tackling AKI: Better care, shorter hospital stays, but no mortality benefit.
๐ NINJA: 23.8% reduction in nephrotoxic AKI across centers.
๐ก The future of AKI prevention lies in system-level interventions!
#KidneyWk 2026 | AKI care gaps
โ ๏ธ Patient education and post-AKI follow-up remain inadequate.
4๏ธโฃ priorities:
1๏ธโฃ Early recognition
2๏ธโฃ Better discharge communication
3๏ธโฃ Structured follow-up
4๏ธโฃ Global implementation (ISN 0by25 & 5R)
AKI care must extend beyond hospital discharge
