Proud to see our international team’s work on the cover of @TheLancetNeuro!
Neurotrauma can affect health for decades. We call for regular screening and coordinated care to improve long-term outcomes.
thelancet.com/journals/laneu…
#TBI #SpinalCordInjury @MGBResearchNews @harvardmed
Saef Izzy retweeted
Our new preprint by @peowenlu @SaefIzzy @weinerlabhms and colleagues shows that nasal anti-CD3 monoclonal antibody treatment can reduce neuroinflammation in a mouse model of Long COVID, even when administered at 4 weeks after infection 🧠
biorxiv.org/content/10.64898…
Saef Izzy retweeted
New review highlights how stem cell therapies may boost stroke recovery by teaming up with the immune system to reducing inflammation, protecting brain tissue, and supporting repair.
Read more from @SaefIzzy and colleagues: pubmed.ncbi.nlm.nih.gov/4123… @BWHNeuroICU @BWHNeurology
Saef Izzy retweeted
A new study shows people with spinal cord injuries are more likely to develop chronic disorders. The study was published in @JAMANetworkOpen.
Read more: massgeneralbrigham.org/en/ab… jamanetwork.com/journals/jam…
@SaefIzzy
Saef Izzy retweeted
While part of the research team is at AAN, @SaefIzzy is presenting in Vienna at the #ADPD2025 conference on his groundbreaking research. Congrats, Saef! #Neuroscience #braininjury #neuro #mgbneurocritical #neurocritical
Saef Izzy retweeted
Congratulations to the 2024 Stepping Strong Breakthrough Award recipient, @SaefIzzy, MD, on his feature in the @BostonGlobe for his development of a nasal therapy that reduces neuroinflammation after a traumatic brain injury (TBI).
bostonglobe.com/2025/03/25/m…
Honored to speak at the National Academies of Sciences, Engineering, and Medicine workshop on TBI as a Chronic Condition. Excited to discuss long-term impacts and strategies to improve care. Join us!
Saef Izzy retweeted
Nasal anti-CD3 monoclonal antibody ameliorates traumatic brain injury (#TBI), enhances microglial phagocytosis and reduces neuroinflammation via IL-10-dependent Treg–#microglia crosstalk in mice
@saefizzy @weinerlabhms
nature.com/articles/s41593-0…
Saef Izzy retweeted
The findings of a study in @NatureNeuro suggest that nasal anti-CD3 represents a promising new therapeutic approach for treating traumatic brain injury and potentially other forms of acute brain injury. go.nature.com/3QGBpQK
ALT This is figure 3, which shows that nasal aCD3 modulates the microglial inflammatory response after TBI.
Nasal Spray Offers Hope for TBI! Our Nature Neuroscience study shows nasal anti-CD3 therapy recruits regulatory immune cells to modulate brain inflammation in mouse models of moderate-to-severe TBI—a promising non-invasive treatment on the horizon! nature.com/articles/s41593-0…
Saef Izzy retweeted
Congratulations to @SaefIzzy on his promotion to Associate Professor of Neurology at @harvardmed
Saef Izzy retweeted
Dr. Izzy’s @SaefIzzy new study confirms earlier findings published in #JAMA: Traumatic #Brain Injury raises the risk of long-term #cardiovascular and neurological issues, =critical need for early screening and prevention!
jamanetwork.com/journals/jam…
Saef Izzy retweeted
The Stepping Strong Center is pleased to announce the 2024 Stepping Strong Breakthrough Award winner:
Congratulations, Dr. @SaefIzzy!
Dr. Izzy will study a potential treatment for spinal cord injury (SCI) that nasally administers anti-CD3 monoclonal antibody.
Saef Izzy retweeted
Huge congratulations to @SaefIzzy for winning 2024 Stepping Strong Breakthrough Award for his research on neuroinflammation treatment targets for #spinalcordinjury #TBI #traumaticbraininjury #neuroscience #NIH🏆 #mgbneurocritical @BrighamWomens @BWHNeurology
Saef Izzy retweeted
Throwback to #ncs2024 - second year #mgbneurocritical fellow Sandro’s poster and faculty @SaefIzzy on the ⬆️ incidence of #cardiovascular disease after #TBI in young patients. They followed patients after TBI for 20 years and find a sig ⬆️ in ❤️ risk
Saef Izzy retweeted
Is it appropriate to share clinically relevant research results with active-duty Special Operations Forces?
We explore ethical, legal & operational perspectives, with the goal of empowering Operators who seek information about their brain health.
osf.io/preprints/psyarxiv/v6…
Saef Izzy retweeted
Congrats to faculty @SaefIzzy on an excellent presentation at @neurocriticalcaresociety regarding anti-inflammatory therapies to directly treat edema and secondary injury resulting from #TBI. #ncs2024 #neurocritical #fellowship #neuroicu #neurocriticalcare #MGBneurocritical
Saef Izzy retweeted
Congratulations @SaefIzzy after your outstanding talk highlighting breakthroughs in the field of #TBI research. We are excited to see where your work at @BrighamWomens will go in the very near future and bring groundbreaking therapies to the field!! @neurocritical #NCS2024
