Sara Gosline (@sargoshoe) header
Sara Gosline (@sargoshoe) profile picture

Computational biologist/data magician @pnnl focused on the interplay between chemicals and the human body. All views my own.

Unceded lands of the Duwamish
Joined October 2008
Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)Photo by Sara Gosline (@sargoshoe)
Register today!
Registration is now open for #SACB2025! Please register at web.cvent.com/event/00434ed6… to hear about the latest systems approaches to cancer biology.
3
3
418
Our team is looking for a Post Masters Research Assistant! If you're interested in doing some really cutting edge Mass Spectrometry Imaging and Method Development, please apply! @PNNLab @asmsnews @IMSSNews careers.pnnl.gov/jobs/9932?l…
7
8
1,229
Sara Gosline retweeted
Probabilistic Uncertainty xkcd.com/3007
39
492
33
6,282
179,821
There is still time to apply to be a #SACBScholar at #SACB2025! If you or someone you know is interesting in learning more about cancer systems biology please apply to our SACB Scholars program sacbmeeting.org/scholars.htm…. We extended the deadline to December 2, 2025.
4
5
423
Missed this deadline? If so you can still send in an abstract by November 8 (this Friday!). We particularly encourage submissions in the areas of Targeting Signaling Transduction, Metabolism at Scale, or Immunology & Host-Tumor Interactions. sacbmeeting.org/registration…
Abstracts are due this Friday for #SACB2025! A great meeting for those who are employing systems approaches in cancer. We have an incredible array of speakers and a fantastic new location near Denver, Colorado.
7
11
1,101
50
13,636
156
118,765
2,683,882
FYI, I'm hoping to fly in a bit early to get a day of skiing in, in case anyone wants to join me ;)
Abstracts are due this Friday for #SACB2025! A great meeting for those who are employing systems approaches in cancer. We have an incredible array of speakers and a fantastic new location near Denver, Colorado.
1
6
666
Me at 7:00 AM this morning
3
113
This meeting is a great opportunity to grow your network in cancer systems biology through presenting your work and growing your network. This community is incredibly supportive and welcomes all!
Systems approaches to cancer biology meeting (SACB2025) is coming up! The abstract deadline and application to be part of our SACB 2025 Scholar program is Friday, November 1. Check out the details at sacbmeeting.org
3
12
1,055
Choosing to leave academia is not the same as quitting science 💀
38
153
26
1,497
158,719
PNNL Linus Pauling Distinguished Postdoctoral Fellowship 2025 is now open to receive applications. Deadline is on Nov 10th at 5 pm PST. Please forward this announcement to those who may be interested in an exciting career at PNNL. careers.pnnl.gov/jobs/9425?l…
19
54
5,022
Postdoc positions available! Carpenter-Singh lab Broad Institute of Harvard and MIT Cambridge MA USA $70,000 (more with years of experience post-PhD) flexible start date See next post for project details... Pls RT! More here/apply: docs.google.com/document/d/1…
9
137
8
249
44,842
Don't forget to register for #RSGDREAM2024 happening in Madison Oct 1-3rd. Learn about key recent advances in statistical, ML and computational genomics methods to problems in gene regulation across a diversity of basic and transitional research areas!
With its smaller size compared to ISMB and RECOMB, this is a good opportunity for trainees to catch some 1-on-1 time with keynote speakers and other attendees...
1
3
5
732
The Kruskal-Wallis test is a non-parametric method used to determine if there are statistically significant differences in the distributions of three or more independent groups based on ranks. Unlike ANOVA, it does not assume a normal distribution, making it versatile for analyzing non-normally distributed data sets. Advantages of proper use: ✔️ Suitable for ordinal data or non-normally distributed data sets. ✔️ No assumption of homogeneity of variance, offering more flexibility. ✔️ Can be used with small sample sizes, increasing its applicability in various research settings. Challenges if not handled correctly: ❌ Interpretation can be complex, especially if the test is mistaken for a median comparison when specific conditions aren't met (IID samples, symmetric distributions). ❌ Less powerful than ANOVA when data is normally distributed, potentially leading to less accurate results. ❌ May require post-hoc tests to pinpoint specific group differences, adding complexity. How to apply in practice: 🔹 R: Use the kruskal.test() function from the base package to perform the Kruskal-Wallis test. 🔹 Python: Utilize the kruskal() function from the scipy.stats module for the analysis. The visualization accompanying this post compares ANOVA and the Kruskal-Wallis test by ranks. This visualization is adapted from a Wikipedia source: en.wikipedia.org/wiki/Kruska… For those interested in learning more, consider joining my online course on Statistical Methods in R, starting on September 9, 2024, where we explore this topic and related methods in greater detail. More info: statisticsglobe.com/online-c… #RStats #DataAnalytics #coding #statisticians #database #Rpackage
7
195
7
1,203
101,635
REMINDER: The Jewish High Holidays are coming up. Don't schedule meetings on these days: - Rosh Hashanah: Sundown 10/2- 10/5. - Yom Kippur: Sundown 10/11- 10/12. Other nearing major but less known holidays - Sukkot: Sundown: 10/16-19 - Shmini Atzeret: Sundown 10/23-10/26
93
4
274
17,137
Exciting day at @PNNLab- @NabaLabUIC is here to talk to all of us about extra-cellular matrix proteins and her @Matrisome work!
3
166