IMPRS PhD student at the MPI of Biochemistry (@labs_mann)
Joined October 2020
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Excited to share that I successfully defended my PhD this week 👩🏼🎓🎉 Thanks to everyone at @labs_mann and beyond that was involved over the last years for all the great collaborations and support!!
Congratulations on earning your #PhD @ssteigerwald13!
Wishing you all the best as you continue your research journey and pursue new projects in the future.
Sophia Steigerwald retweeted
We just release alphaDIA 1.8.2 including some new step-by-step guides for #Proteomics.
Learn how to:
• Run DIA searches from the GUI
• Create custom PTM models with DIA transfer learning
• Evaluate model performance with detailed metrics
alphadia.readthedocs.io/en/l…
#TeamMasSpec
Interested in learning more about how we utilized our DVP pipeline to study Alpha-1 antitrypsin deficiency? Preprint and and a fantastic Tweetorial from @labs_mann and @metaboflo are out now 🔬🎉#Alpha1Awareness
AATD affects thousands, causing liver & lung disease via protein aggregation. Our new preprint used #DeepVisualProteomics to study liver cells and reveals key AATD insights with clinical implications . Video and tweetorial @metaboflo #Alpha1Awareness
bit.ly/4hzl64o
Very honored to have won the ECR poster competition for our work on single cell DVP of alpha-1 antitrypsin deficiency 🥳Special shoutout to @metaboflo for letting me lead the scDVP efforts in this project and for everyone interested, keep your eyes peeled 👀 #Alpha1Awareness
Fantastic time at #HUPO2024 in Dresden! Proud of our @labs_mann team - @ssteigerwald13, @NordmannThierry and Ericka Itang for sweeping up awards with best poster prizes in grad & postdoc categories, plus the 3-minute thesis competition! #ScientificExchanges #NewCollaborations
Sophia Steigerwald retweeted
We are excited to invite you to this networking event at @hupo_org World Congress 2024!
📅 22nd of October, 12-14 PM
📍 Seminar Room 1, International HUPO, Dresden, Germany
Please, register here: docs.google.com/forms/d/e/1F…
Let's meet and discuss the following important topics! 👩🏫
Sophia Steigerwald retweeted
Published today! Spatial proteomics reveals JAK/STAT as a target for Toxic Epidermal Necrolysis, an often fatal skin reaction to common medication. We validated our findings in pre-clinical models & successfully treated the first patients worldwide.🧵⬇️ nature.com/articles/s41586-0…
Sophia Steigerwald retweeted
If you are at #hupo2024 in Dresden, do catch up with our lab-mates to know more about some of our exciting research in @labs_mann
👇
Sophia Steigerwald retweeted
❗ Registration for the Round 5 Mentorship Pods is OPEN!
More information: femalesinms.com/mentorship-p…
Registration: airtable.com/appiw25tkvnETe5…
🔆Everyone is welcome and encouraged to participate🔆
Sophia Steigerwald retweeted
One patient, four organs, many insights: We applied Deep Visual Proteomics to track protein changes in Signet Ring Cell Carcinoma. This spatial analysis could pave the way for more targeted therapies in rare tumors #PrecisionOncology #DeepVisualProteomics
doi.org/10.1101/2024.08.07.6…
Sophia Steigerwald retweeted
Incredibly proud of Matthias Mann for winning this year's Dr. H.P. Heineken Prize for Biochemistry and Biophysics together with Ruedi Aebersold! Their pioneering work has transformed protein research and is reshaping the future of biomedicine! #proteomics
heinekenprizes.org/2024/06/1…
Congratulations to Matthias Mann who receives the prestigious #HeinekenPrize for Biochemistry and Biophysics with Ruedi Aebersold for ‘revolutionizing the way proteins are studied’.
❕heinekenprizes.org/2024/06/1…
❕biochem.mpg.de/mann
@labs_mann #proteomics
Sophia Steigerwald retweeted
How does space affect #skeletalmuscle in #astronauts aboard the #InternationalSpaceStation? Our #proteomics study shows significant changes in the mitochondria -and more- pre and post mission. Dive deeper into our findings here 👉 rdcu.be/dJZ9G #SpaceBiology #myotwitter
Sophia Steigerwald retweeted
My lab @MCF_UoM is #hiring a Research Technician. I'm looking for someone with experience in #iPSC & #microscopy. You will be trained in #proteomics and the project will tackle the mechanisms underlying rare neurological diseases.
Apply now!
jobs.manchester.ac.uk/Job/Jo…
#pleaseshare
Sophia Steigerwald retweeted
AlphaDIA enables End-to-End Transfer Learning for Feature-Free Proteomics biorxiv.org/cgi/content/shor… #biorxiv_bioinfo
Sophia Steigerwald retweeted
7/7 We encourage everybody to install and use it (should be easy). Check out the Github page at github.com/MannLabs/alphadia
Sophia Steigerwald retweeted
1/7 @labs_mann and Georg Wallmann @GeorgWa are proud to announce alphaDIA, our open source, next generation DIA search engine. Check out the preprint @biorxivpreprint
biorxiv.org/content/10.1101/…
Sophia Steigerwald retweeted
In collaboration with @JensenLab_UCPH, we drastically improved the sensitivity of our Deep Visual Proteomics workflow, examined the proteome of human colon mucosa & organoids, which revealed a switch to an in vivo-like phenotype upon xenotransplantation.
biorxiv.org/content/10.1101/…
Sophia Steigerwald retweeted
I am thrilled to share that I have successfully defended my PhD thesis! A heartfelt thank you to everyone at @labs_mann, @MPI_Biochem and @BrukerMassSpec for their amazing support along this unique journey. Excited for what’s next! #Grateful #phdlife
Congratulations on earning your #PhD!
Wishing you all the best as you continue your research journey and pursue new projects in the future.
@labs_mann @patiskowronek
Sophia Steigerwald retweeted
Congratulations on earning your #PhD!
Wishing you all the best as you continue your research journey and pursue new projects in the future.
@labs_mann @patiskowronek
Sophia Steigerwald retweeted
Tenure-track Group Leader positions available at the Max Planck Institute of Biochemistry @MPI_Biochem. Open to researchers from all fields with potential to synergize with our ongoing research. Female candidates are strongly encouraged to apply. Deadline: April 11th.
We are seeking outstanding researchers for group leader positions, including through the tenure track Lise Meitner Excellence Program!
Contact us to discuss a potential fit with our ongoing research at:
❕[email protected]
❕biochem.mpg.de/Research
Sophia Steigerwald retweeted
Thrilled to announce our AlphaPept paper out in @NatureComms: doi.org/10.1038/s41467-024-4…. It's the cornerstone of our AlphaX-ecosystem: #proteomics, #opensource , #Python, notebooks and GPU. A big shout out to an amazing collaboration!
@numba_jit
@nvidia
@streamlit
@jeremyphoward
