Systems Medicine @ SciLifeLab (@sysmedicine) header
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Systems Medicine Group at @scilifelab and @KTHuniversity, Sweden. Group Leader: Dr. Adil @Mardinoglu

Stockholm, Sweden
Joined July 2018
2021 has been a really good year for our group. Thanks to our amazing group members and collaborators!
2021 was a fantastic year for us and our collaborators. In 2021, we published >52 papers (one per week), filed 3 patent applications and our previous publications were cited >5700 times. Many thanks to our team members and collaborators.@SaeedShoaie @HasanTurkez @mujdatzeybel
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Systems Medicine @ SciLifeLab retweeted
Our multi-omics paper on the analysis of CMA supplementation clinical trial is out! Comprehensive application of systems biology and network analysis in the integration of 4 different omics and clinical variables.
Oral administration of Combined Metabolic Activators (CMA) reduces liver fat in nonalcoholic fatty liver disease patients --> bit.ly/3vHr9fv @Mardinoglu @KTHuniversity @kingsdentistry J Boren @goteborgsuni #NAFLD
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Systems Medicine @ SciLifeLab retweeted
hey twitter, we'll have a really cool open seminar tomorrow (8th Sep) at 3PM CET on Zoom and Youtube! "Network based analysis of 1002 GWAS study defines a pleiotropy map of human cell biology" Dr. Pedro Beltrao, EMBL-EBI @scilifelab @NBISwe @emblebi
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Systems Medicine @ SciLifeLab retweeted
Our study about the use of combined #metabolicactivators in #Alzheimers Disease patients has been published in a preprint server @medrxivpreprint
Combined Metabolic Activators Improves Cognitive Functions in Alzheimer's Disease medrxiv.org/cgi/content/shor… #medRxiv
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We used a wide range of systems biology tools to analyze multi-omics data from the clinical trials (Phase 2 and 3), complemented with detailed clinical variables of the patients. This study suggested a role for such a therapeutic regime in complex diseases, including COVID-19.
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Today, one of the PhD students in our group has successfully defended his thesis. Congratulations, Dr. @muharif !!
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The comprehensive summary of his thesis can be found on this link: kth.diva-portal.org/smash/re…
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Systems Medicine @ SciLifeLab retweeted
Plus, I have also attempted to make accompanying popular science summary of my latest paper about "what is happening during a heart attack?" based on our latest paper on multi-tissue transcriptomics analysis after myocardial infarction. blog.muharif.net/WhatIsHappe…
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We were able to identify global and tissue-specific gene clusters that showed an important response to MI. We were also able to identify dysregulation in multiple biological processes also tissue-specific dysregulation in biological processes in the liver and heart.
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We hope that this study can contribute significantly to the field of systems biology and cardiovascular disease research. Lastly, we would like to thank all contributors and collaborators for their supports in this study.
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