@twmarkc

A Pathologist & Cytopathologist in Taiwan. Interests in Cancer biology, Cyto, Hema, Bioinformatics. Ex President of Taiwan Society Clinical Cytology.

 Taiwan
researchgate.net/profile/Chienchin_Chen/contributions
Joined September 2013
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  • Followers1.2K
Replying to @IACytology
@IACytology @AshishC97225686 Thank Ash and Gary for hosting the IAC webinar. Allison and Carmen kindly helped the recording. I'm really thankful for over 200 online participants for those two talks. Grateful for the opportunity of doing contribution. youtu.be/8v4-heveFio?si=316D…
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Cancer Cytopathology@CancerCytopath
Sep 17
🔬 Free access | Diagnostic challenges in urinary cytology: Practical insights from The Paris System for Reporting Urinary Cytology acsjournals.onlinelibrary.wi… #CytoPath #ParisSystem @cjvand
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nature
@Nature
Sep 7
Nature review: Molecular mechanisms and pathogenesis of MASH go.nature.com/4i5T1V3

Molecular mechanisms and pathogenesis of MASH

Nature - This Review highlights the state of the art of molecular and cellular mechanisms underlying MASH pathogenesis and its transition to hepatocellular carcinoma.

nature.com
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David Kalfert@DavidKalfert
Sep 8
New publication in Cancer Cytopathology! 🎉🇫🇮🇨🇿 Our Finnish–Czech collaboration on rare primary pulmonary salivary gland-type tumors: overall cytohistologic concordance 48.1%, with FNA performing best (75%). Many thanks to Henri Lagerstam & Ivana Kholová doi.org/10.1002/cncy.70153 – at Horoměřice, Česká republika

Primary pulmonary salivary gland‐type tumors in cytopathology practice: A systematic review and...

This systematic review identified 49 studies on the cytologic diagnosis of primary pulmonary salivary gland-type tumors involving 106 patients. Among cytologic sampling methods, fine-needle aspirat...

acsjournals.onlinelibrary.wiley.com
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Let's join the survey. I completed the survey right after I got the email.
Vanda Torous MD@VandaTorousMD
Aug 10
Dear cytologists/cytopathologists The American Society of Cytopathology needs to hear from you! Please fill out this important survey on the impact of the CMS memorandum on digital cytology 👉 surveymonkey.com/r/3QQJLXJ #CytoPath #Cytopathology #Pathology #Pathologists
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Dvir Aran
@dvir_a
Sep 1
Our paper is out in @Cancer_Cell! We started this project almost 5 years ago with the idea that to understand why some cancer patients respond to immunotherapy and others do not, we may need to look beyond the tumor before treatment. Immunotherapy is not just a test of a pre-existing state; it is a perturbation. It changes the tumor immune microenvironment. So the question became: can the direction of that change explain response? authors.elsevier.com/a/1niWC…
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Waggoner Lab@LabWaggoner
Aug 31
Review: Decoding T cell exhaustion in the tumour microenvironment nature.com/articles/s12276-0…
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Cancer Cytopathology@CancerCytopath
Sep 1
📢 Beyond the adult standard: Tailoring the WHO Reporting System for Lymph Node Cytopathology to pediatric diagnostics and management acsjournals.onlinelibrary.wi… #CytoPath CC: @IvanaKholova
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Mark CC Chen, M.D. FIAC retweeted
Cancer Cytopathology@CancerCytopath
Aug 28
#OpenAccess | Malignant effusions secondary to metastatic thyroid carcinomas: A review of 15 cases. Ancillary testing is extremely helpful in arriving at the correct diagnosis. acsjournals.onlinelibrary.wi… #CytoPath CC: @Sinchita_Roy
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Interobserver variability does not explain the limited predictive value of PD-L1 TPS in the neoadjuvant setting. PD-L1 has an intrinsic limitation. sciencedirect.com/science/ar…
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Syed A. Ahmad@SyedAAhmad5
Aug 26
Biomarker-Driven Management of Nonmetastatic GEJ Adenocarcinoma @annsurgoncol link.springer.com/article/10…

Biomarker-Driven Management of Nonmetastatic GEJ Adenocarcinoma

Annals of Surgical Oncology - Advances in understanding the molecular landscape of gastroesophageal junction (GEJ) adenocarcinoma underscore the need for biomarker-driven treatment approaches. The...

link.springer.com
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Mark CC Chen, M.D. FIAC retweeted
Cytopathology@CytopathologyJ
Aug 25
🤔 Once in a career, you may encounter a pleural effusion case like this. When that moment comes, you'll be glad you've seen it before in the literature. #Cytopath #CytoJ ⬇️ doi.org/10.1111/cyt.70108

Unique Presentation of Metastatic Malignant Germ Cell Tumour Diagnosed on Pleural Effusion Cytology

Click on the article title to read more.

onlinelibrary.wiley.com
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Cancer Cytopathology@CancerCytopath
Aug 26
#OpenAccess! Scrape cytology showed significantly higher diagnostic performance than imprint cytology, particularly after patients received neoadjuvant therapy. acsjournals.onlinelibrary.wi… #CytoPath @glinglerimek
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Lola Lozano@mdlozanoe
Aug 19
Signet-ring cell gastric carcinoma in peritoneal fluid. In effusions, malignant cells may change their morphology to fool us -😎🧐🕵️‍♀️- but not this time! Bottom right: CDX2 nuclear positivity (smear) @IACytology @CytologyEFCS @cytopathology @SEAP_IAP
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NEJM
@NEJM
Aug 19
A new review summarizes the pathogenesis and treatment of myeloproliferative neoplasms, highlighting the role of driver mutations, inflammation, and emerging targeted therapies that may achieve durable disease modification. Read the Review Article “Myeloproliferative Neoplasms” by Isabelle Plo, PhD, and William Vainchenker, MD, PhD: nej.md/4wD0AWG
An illustrated diagram from the Review Article "Myeloproliferative Neoplasms" that shows the main structures and functions of the myeloproliferative neoplasm driver mutations. Panel A shows a schematic representation of Janus kinase 2 (JAK2) in its inactive state on the thrombopoietin receptor (MPL) and in the active conformation induced by the MPL mutations or calreticulin (CALR) mutations. Panel B shows the mechanisms of oncogenic signaling activation. Mutant CALR binds to MPL monomers in the endoplasmic reticulum and travels through the canonical secretory pathway to the cell surface.

ALT An illustrated diagram from the Review Article "Myeloproliferative Neoplasms" that shows the main structures and functions of the myeloproliferative neoplasm driver mutations. Panel A shows a schematic representation of Janus kinase 2 (JAK2) in its inactive state on the thrombopoietin receptor (MPL) and in the active conformation induced by the MPL mutations or calreticulin (CALR) mutations. Panel B shows the mechanisms of oncogenic signaling activation. Mutant CALR binds to MPL monomers in the endoplasmic reticulum and travels through the canonical secretory pathway to the cell surface.

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Syed Z. Ali
@sza_jhcyto
Aug 19
Textbook cytomorphology of Hepatocellular Carcinoma, Fibrolamellar type in a teenage boy, with malignant cells presenting a sharp contrast with the trapped biliary epithelium. (Liver, FNA)
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Cancer Cytopathology@CancerCytopath
Aug 19
New this week and #OpenAccess! 🔬 Cytodiagnostic features of angiofibroma of soft tissue: A review of 16 cases to identify characteristic findings and their diagnostic significance acsjournals.onlinelibrary.wi… #CytoPath CC: @MichiyaNishino
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Moderna cancer vaccine stops melanoma returning: what’s next for personalized treatments? nature.com/articles/d41586-0… It is still a long way from proving the efficacy of personalized cancer vaccines. But this phase III result in melanoma provides new insights into cancer immunity.

Moderna cancer vaccine stops melanoma returning: what’s next for personalized treatments?

Nature - Promising trial results suggest cancer vaccines work and could be used to target other tumours.

nature.com
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Cancer Cell@Cancer_Cell
Aug 12
Subclinical cholestasis is a hallmark of gut dysbiosis causing resistance to cancer immunotherapy dlvr.it/TTzjlT
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International Academy Cytology@IACytology
Aug 13
#IACwebinar Friday, 14 August 2026 Doing more with less: Immunohistochemistry / Immunocytochemistry in Small Biopsies / Cytology Specimens Prof. AndrewBellizzi @IHC_guy Time: 2:00 PM CEST / 8AM EDT(USA) Access is limited to #IACmembers, available in our website members area!
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Cancer Cytopathology@CancerCytopath
Aug 11
New this week 🔬 Diagnostic performance of artificial intelligence models trained on scattered single-cell images is not preserved for hyperchromatic crowded cell groups in cervical cytology acsjournals.onlinelibrary.wi… #CytoPath #GynPath CC: @MichiyaNishino
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