Total Recall is upon us. 🧊🧠
View the full proposal and vote: snapshot.org/#/s:vote.cryoda…
officially announcing the next @cryodao research project:
$259,000 for "TOTAL RECALL" 🧊🧠
setting out to prove that complex mammalian memory can survive cryopreservation with legendary cryobiologist greg fahy and principal investigator regina monaco
two complementary approaches will be pursued: testing whether learned responses survive cryopreservation in neural cultures and/or hippocampal slices, and whether the molecular changes associated with training are preserved
together, these approaches target one of the central questions for cryopreservation: can the information underlying memory survive?
Cryopreservation is hard.
Read: "Overcoming Perfusion Impairment in the Ischemic Brain: A Review"
🧊🧠
Cryopreservation is hard. Not least because perfusion under adverse conditions is difficult to do right. Ischemia is clearly the most common and most complex to handle.
We just published our thoughts here: "Overcoming Perfusion Impairment in the Ischemic Brain: A Review"
mdpi.com/2673-4087/7/4/89
Thanks to all co-authors: Andrew T. McKenzie, Aschwin de Wolf, Alexander Grotemeyer, and Alexander German
Austin Lynch retweeted
it is not enough to save the living
we must also reclaim those whom death has already taken
for there is no greater injustice than accepting death as final
this is the work to which we have been called
we undertake what no one else dares, so that one day, none shall be beyond our reach
for if no one begins, no one will ever return
Austin Lynch retweeted
still with the same guys I started it all with
nitter.cf/kaimicahmills/status/5…
Austin Lynch retweeted
Our friends are launching Fund Longevity and taking longevity advocacy to the streets.
📍 one of 16 cities or online!
📣 spread the word!
@LinusPeters @vladileshko @longevitynastya
Austin Lynch retweeted
bodyoids may be the key to extending human lifespan
beyond perfectly-matched replacement organs and tissues whenever you need them, imagine replacing everything all at once, instead of piece by piece
a head or brain transplant onto a brand new body, a clone of yourself, when your current body can no longer be repaired
scientists have both successfully cloned primates and performed head transplants on primates
in fact, the reason the primate died 9 days after the head transplant, in the 1970s, was due to the body rejecting the head - something a clone bodyoid would solve
arpa-h recently launched a program called front with hundreds of millions of dollars working on progressive replacement of the brain, the one piece we of course cannot swap out entirely
at hydradao we now have rats, rabbits, and even pigs walking days after complete transection of the spinal cord, ensuring a head transplant would not lead to quadriplegia
pieces of the puzzle are coming together to form a path towards radical life extension that doesn't require us to solve the mysteries of aging
bodyoids are at the center of it all
the ultimate solution is through technology
we engineer what has been called a bodyoid: brainless animal bodies that provide as much meat as we desire without harming any sentient beings
this would transform medicine - the same platform would allow us to grow organs on demand, eliminate transplant waiting lists, and produce perfectly matched tissues for each patient
experimental therapies could be tested on full biological systems without involving conscious animals, regenerative medicine would accelerate as entire replacement tissues become manufacturable
in the same way that agriculture turned food from a scarce resource into an abundant one, engineered bodyoids would turn biological material into infrastructure - meat without slaughter, organs without donors, and medical research without sentient suffering
Austin Lynch retweeted
the bodyoid faq:
- how would bodyoids exist without a brain?
biology already gives examples - in rare conditions like hydranencephaly, large portions of the brain, including the cerebral hemispheres, fail to develop
the body still forms, organs grow, and many basic physiological systems function, but the neural architecture required for consciousness never emerges
a bodyoid would apply the same principle intentionally: allow normal body development while preventing formation of the structures associated with sentience - development continues, tissues mature, organs grow, but the organism never forms a conscious brain
- why not just do cultured meat?
cultured meat may work for simple tissues, but biology already knows how to build vascularized muscle, fat marbling, connective tissue, skin, and bone - a bodyoid lets development do the work
we then also unlock organs on demand, blood, skin, collagen, and countless other biological materials
also, people clearly don't find it good enough
- why doesn't everyone just stop eating meat?
good luck
- are you jewish?
no
- is this science fiction?
no - we are actively funding labs with millions of $$ working on brainless clones and other steps of this process via @daohydra, some of whom have already had successes in small mammals (mouse bodyoids that lack consciousness, have no head/arms/legs, only a tail, which they are still working to remove)
- why not just print organs?
bioprinting is promising but extremely difficult at full scale - organs are dense vascular systems with billions of cells arranged precisely, a bodyoid grows them naturally
- are human bodyoids next?
hopefully! the bottleneck in modern medicine is biological material
right now, people die waiting for organs - kidneys, hearts, livers, lungs, skin grafts, bone, blood products - demand vastly exceeds supply
a human bodyoid platform would mean organs on demand - clones would mean perfectly matched tissues grown for each patient - no waiting lists, no rejection, no need to rely on deceased donors
it would also transform trauma care and surgery where severe burns could receive unlimited skin grafts, damaged organs could be replaced rather than managed, experimental therapies could be tested on full biological systems without involving conscious humans, and the list goes on
so, yes, you should want your own personal bodyoid
- this is evil/an abomination/going against god/etc/you should be burned at the stake
you should see what we do to the real pigs - ethically speaking, this is essentially a meaty plant
bodyoids are coming :)
btw, I have enjoyed many hours reading hundreds of very funny comments, thank you
the ultimate solution is through technology
we engineer what has been called a bodyoid: brainless animal bodies that provide as much meat as we desire without harming any sentient beings
this would transform medicine - the same platform would allow us to grow organs on demand, eliminate transplant waiting lists, and produce perfectly matched tissues for each patient
experimental therapies could be tested on full biological systems without involving conscious animals, regenerative medicine would accelerate as entire replacement tissues become manufacturable
in the same way that agriculture turned food from a scarce resource into an abundant one, engineered bodyoids would turn biological material into infrastructure - meat without slaughter, organs without donors, and medical research without sentient suffering
There are no good arguments against this beyond aesthetics. All the quotes are unable to explain themselves beyond it "being obvious". Humans already do this shit with animals that have a pre-frontal cortex and that's like infinity times worse.
the ultimate solution is through technology
we engineer what has been called a bodyoid: brainless animal bodies that provide as much meat as we desire without harming any sentient beings
this would transform medicine - the same platform would allow us to grow organs on demand, eliminate transplant waiting lists, and produce perfectly matched tissues for each patient
experimental therapies could be tested on full biological systems without involving conscious animals, regenerative medicine would accelerate as entire replacement tissues become manufacturable
in the same way that agriculture turned food from a scarce resource into an abundant one, engineered bodyoids would turn biological material into infrastructure - meat without slaughter, organs without donors, and medical research without sentient suffering
Austin Lynch retweeted
those of us who played SOMA growing up learned this lesson early on
transhumanism's mistake was making identity abstract - it was no longer continuity that mattered, no longer *you*, but rather a pattern or data
I attended an event a few weeks back where a speaker advocated that for immortality we did not need to keep continuity, and in fact we did not even need brain preservation at all - we simply needed a robust enough collection of our social media posts, pictures, etc, and we could recreate a convincing enough version of ourselves
this is the culmination of this way of thinking - you no longer matter; a crude puppet with similar enough features will suffice, and in fact that is you in every way that matters
there is an entire subset of the cryo field focused on fixation due to their belief that biological viability does not matter
it is fundamentally anti-human and deathist - this was one of the first dangerous ideals that detached us from cosmism, the last true anti-death ideology, and thus began the slippery slope that lead us to a deathist culture in the longevity field today
Austin Lynch retweeted
one thing that makes me sad about the I Am Sober app is that i can see how many people are on this journey with me, awaiting their next milestone.
when i first joined, it was about 12,000 people. at 6 months, it was 6,000. and now...
Big man Darth gets up to very important CryoPets business in his new office. He's our most efficient hire.
Austin Lynch retweeted
decentralized science has the opportunity to fund and advance frontier life extension technologies that would otherwise be neglected for decades
but desci is a deeply broken field
"agentic science" nonsense, grifters, useless tokens, memecoins, fake research...
we spent the week in argentina with the real builders, scientists and investors who want to see this space work and create true impact
we've been building our ecosystem of cryo, hydra, and more for years now, and soon we will release an engine that enables us to 1000x our speed and reach
what is coming is inevitable, not because it always was, but because we will make it so

































