Dane M. Wolf (@DaneMWolf) header
Dane M. Wolf (@DaneMWolf) profile picture

Mitochondrial scientist.

Joined October 2019
Photo by Dane M. Wolf (@DaneMWolf)Photo by Dane M. Wolf (@DaneMWolf)Photo by Dane M. Wolf (@DaneMWolf)Photo by Dane M. Wolf (@DaneMWolf)
Dane M. Wolf retweeted
A tremendously collaborative effort led by co-first authors: @molecularpepsi (our amazing former postdoc), @joevisker, @jn_velascosilva, and James Carrington (our awesome grad student)! Congrats to all authors, co-senior authors @gsducker and @StavrosDrakos, and everyone who contributed!
I'm very happy to share the final version of our paper, “MCT1-dependent mitochondrial lactate import sustains cardiac metabolism,” out in Nature! We show how lactate fuels heart mitochondria and helps protect the heart during stress. nature.com/articles/s41586-0… @UofUBiochem 1/10
9
2
76
3,982
Dane M. Wolf retweeted
Coming up in EMBO J today: Mitochondria play with lipid droplets: link.springer.com/article/10…
8
22
1,234
So grateful for the opportunity to chat about energy, mitochondria, and health with @hubermanlab. Would love to hear your thoughts and lived experiences if anything resonates particularly strongly.
The new Huberman Lab episode is out: Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard (@MitoPsychoBio) 0:00 Martin Picard 3:50 What is Energy?, Energy Flow & Transformation 7:53 Energy, Vitality, Emotions, Sensory Perception 14:18 Sponsors: Helix Sleep & Lingo 17:19 “Mito-Centric” View of World, Mitochondrial Energy & Information Patterns 25:26 Organelles, Mitochondria & Energy Transformation; Maternal Genes 31:12 Mitotypes & Differentiation, Mitochondria as “Social Organisms” 36:52 Food & Dysfunctional Energy Transformation 40:02 Lifestyle Choices & Interests, Physiological Growth 46:39 Pregnancy, Amenorrhea; Illness & Tiredness 51:07 Sponsor: AG1 52:29 Energy Transformation & Distribution; Body’s Wisdom, Feeling Sick 56:27 Tool: Feel Your Energy; Breath & Energy 1:02:31 Flow of Energy; Trade-Offs, Life Purpose & Enjoyment 1:10:15 Biology, Meaningful Experiences & Energy Flow 1:16:27 Sponsor: Function 18:15 Inflammation, Energetic Flow 1:20:43 Child Prodigies, Species Lifespan & Mitochondrial Metabolism; Aging 1:28:56 Lifestyle & Aging: Exercise, Fasting; Inflammation, Sleep, Stimulants 1:37:06 Energetic Stress Signals, GDF-15, Cancer, Heart Failure 1:42:18 Genes, Lifestyle & Aging 1:47:54 Gray Hair Reversal, Stress; Inflammation & Aging 1:57:37 Energy Recovery, Sleep & Mitochondrial Function, Stress, Meditation 2:05:16 Tools: Yoga Nidra, NSDR; Pre-Sleep Relaxation, Energy & Restorative Sleep 2:10:58 Diet & Individualization, Clinical Trials; Mitochondria & Nutrition, Keto 2:20:14 Alcohol & Energy Budget; Stress 2:25:02 Exercise, Increase Mitochondria, Overtraining; Resistance & Growth 2:33:06 Sponsor: Waking Up 2:34:41 Supplements & Mitochondria Health, Deficiencies, SS31, Methylene Blue 2:41:31 Energy Flow & Experiences, Balance 2:49:13 Transform Through Resistance, Energetic Awareness, Connection 2:56:05 Food Overconsumption & Mitochondria Disruption; Tissues & Mitochondria 3:01:02 Mitochondrial Health Test; Tool: Ways to Increase Energy; Meditation 3:06:10 Peptides; Fertility Supplements, Urolithin A; Electromagnetic Fields 3:12:16 Acknowledgements 3:14:15 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter Includes paid partnerships.
31
34
2
372
77,320
Thrilled to see @MitoPsychoBio bringing mitochondrial biology into focus on the @hubermanlab podcast! Check out this great discussion, which highlights the central role of mitochondria in health and longevity: youtube.com/watch?v=nMkQUlBt…
2
806
Dane M. Wolf retweeted
Massive thank you to our reviewers for improving the manuscript, our funders @The_MRC and @wellcometrust Academy of medical Sciences and the editors @NatureComms
1
4
462
An elegant new study shows that remodeling of mitochondrial morphology and energy metabolism enables cancer cells to survive in acidic tumor microenvironments--more evidence that mitochondria play crucial roles in both health and disease. science.org/doi/10.1126/scie…
3
390
In his 1890 monograph, Richard Altmann described “bioblasts” (now known as mitochondria) as elementary organisms living within the cell. Their social lives are never more apparent than when directly observing their dynamic behaviors, as seen here in a primary liver cell.
1
2
326
Welcome to the Mitoverse 😀 Great introductory piece on mitochondria from @mitoworld_org stemmagazine.com/gOCT25/view…
4
70
4
321
12,759
Mitochondria in liver cells often look like a sunburst, radiating from two nuclei at the cellular center. Read more about the vital role that mitochondria play in our health: stemmagazine.com/gOCT25/view…
288
How does energy keep us alive? Our bodies are resistive energetic circuits where electrons flow from food→oxygen in our mitochondria. It's only through energy resistance (éR) - like electrical resistance - that transformation of energy into life is possible. The Energy Resistance Principle ⎸ ERP explains how this happens. In this paper, we cover the implications of fine-tuning éR for health, disease, aging, and the human experiences make up the mind. authors.elsevier.com/a/1luVK…
33
214
21
847
155,248
We spend so much money to kick the can down the road. Our model of what health is and how to foster it is deeply broken. In 50 years, new generations will look back at 2000-2025 and feel sorry for our science and policies that had things so backwards. Now is a time of change.
Robert F. Kennedy Jr.: "Today, over 100 members of Congress support a bill to fund Ozempic with Medicare at $1,500 a month. Most of these members have taken money from the manufacturer of that product, a European company called Novo Nordisk. As everyone knows, once a drug is approved for Medicare, it goes to Medicaid." "And there is a push to recommend Ozempic for Americans as young as six over a condition, obesity, that is completely preventable and barely even existed 100 years ago. Since 74% of Americans are obese, the cost of all of them, if they take their Ozempic prescriptions, will be $3 trillion a year. This is a drug that has made Novo Nordisk the biggest company in Europe." "It's a Danish company, but the Danish government does not recommend it. It recommends a change in diet to treat obesity and exercise. Virtually Novo Nordisk's entire value is based upon its projections of what Ozempic is going to sell to Americans." "For half the price of Ozempic, we could purchase regeneratively raised organic agriculture, organic food for every American three meals a day and gym membership for every obese American. Why are members of Congress doing the bidding of this Danish company instead of standing up for American farmers and children? Because Novo Nordisk is one of the largest funders of medical research, the media and politicians and the medical schools all go along with them."
11
11
2
55
8,394
Map of functional diversity in mitochondria across the human brain -- very cool! Congratulations @MitoPsychoBio on a groundbreaking study! nature.com/articles/s41586-0…
3
12
653
Dane M. Wolf retweeted
Massive congratulations to @AlvaCasey3 on her first author paper from her PhD: 'Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation' #immunometabolism nature.com/articles/s42255-0…
3
7
1
37
2,534
Textbook oxidative phosphorylation needs to be rewritten with Fernando Abdulkader sciencedirect.com/science/ar… Free for 50 days here: sciencedirect.com/science/ar…
5
43
2
111
8,596
Dane M. Wolf retweeted
For those who missed our recent publication, have a look!
Multi-omics study combined with functional assays reveal mitochondrial apolipoprotein MIC26 located in the inner membrane regulates central cellular fuel pathways in a MICOS-independent manner @KondadiLab @ReichertLab @HHU_de @UniklinikDUS @ReviewCommons hubs.la/Q02TcQVG0
5
17
1,846
Dane M. Wolf retweeted
Thrilled to share the last review of the lab led by @Tabara_LC and @MayukoSegawa on the mechanisms regulating mitochondrial morphology!!! @MRC_MBU Just out in @NatRevMCB. Thanks @lisa_heinke for the smooth editorial process!
Now Online: Molecular mechanisms of mitochondrial dynamics go.nature.com/405NTaf
5
42
2
128
17,906