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Science Magazine

@ScienceMagazine

Cutting-edge research, news, commentary, and visuals from the Science family of journals. Follow @NewsfromScience for stories from our News team.

 Washington, DC & Cambridge, UK
science.org/
Joined April 2009
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Freshwater species face widespread human pressures, but where those pressures affect biodiversity has remained poorly understood. New Science research maps 45 threats across more than 21,000 freshwater species, revealing hotspots of impact and helping guide conservation and management efforts where they are most urgently needed. Learn more in this week’s issue: scim.ag/4jH5Vtm
A fire salamander (Salamandra salamandra) rests beside a forest stream in Bratsigovo, Bulgaria. Freshwater species face widespread human pressures, but where those pressures affect biodiversity has remained poorly understood. Research mapping 45 threats across 21,490 freshwater species reveals hotspots of impact, helping guide conservation and management efforts where they are most urgently needed. Photo: Guy Edwardes/NPL/Minden Pictures

ALT A fire salamander (Salamandra salamandra) rests beside a forest stream in Bratsigovo, Bulgaria. Freshwater species face widespread human pressures, but where those pressures affect biodiversity has remained poorly understood. Research mapping 45 threats across 21,490 freshwater species reveals hotspots of impact, helping guide conservation and management efforts where they are most urgently needed. Photo: Guy Edwardes/NPL/Minden Pictures

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A newly resurfaced photo taken by Rosalind Franklin—photo 49—shows she was aware of the helical structure of DNA and explains why her published image—photo 51—does not have indications of her understanding of its shape. Learn more in the latest episode of the #SciencePodcast🎙️: scim.ag/4BpAwly
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The NOSTER & Science Magazine Microbiome Prize rewards innovative research by early-career investigators on the functional roles of the microbiota in human or veterinary health and disease. Apply by 14 February 2027: bit.ly/4yHVbii
The image shows a blue rectangular logo with the words "Noster Science Microbiome Prize" in bold, white letters.

ALT The image shows a blue rectangular logo with the words "Noster Science Microbiome Prize" in bold, white letters.

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Lisa L. Ouellette@PatentScholar8h
New article in @ScienceMagazine, with Janet Freilich, Kasper Dinkla & Ingmar Meijer, quantifying the gap between claims & disclosure in drug patents & suggesting broad claims are used as strategic "moats" science.org/doi/10.1126/scie…
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🎉 Congratulations to Gioele La Manno, winner of the 2026 Eppendorf & Science Prize for Neurobiology for his innovative experiments that have uncovered intricate layers of organization in the brain’s lipids—and have deciphered how these fatty molecules shape the diversity of brain cells. Learn more: scim.ag/4yQ0tIv
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Bird songs share surprising similarities with human music and speech, according to a large-scale study comparing vocalizations across hundreds of bird species and dozens of human languages. The findings in Science suggest that these similarities may arise partly from shared biological mechanisms, rather than vocal learning ability alone. Learn more: scim.ag/4ikVRUr
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Two proteins that permeabilize mitochondria promote cell death through distinct mechanisms. Learn more in a new #SciencePerspective: scim.ag/4iHh5gH
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In a unique human challenge study, researchers interrogate how preexisting immunity and antibodies against the four serotypes of #dengue influence viremia, T cell responses, and immune activation in a safe and controlled setting. @ScienceTM scim.ag/4yPtDHV
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Although cancer is a common cause of death in domestic cats, little is known about the range of cancer genes in cat tumors, and how this range might compare with the oncogenome in people. Researchers in Science have sequenced cancer genes in 493 samples from 13 different types of feline cancer and matched healthy control tissue, gaining a clearer picture of the cat oncogenome and comparing the genes to known cancer-causing mutations in humans. Learn more on #NationalCatDay: scim.ag/4yK4cHD
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Japan’s MMX mission aims to retrieve samples from Mars’s mysterious moon. They could reveal how it formed—and hold pieces of Mars itself. Learn more: scim.ag/4sgWWRI @NewsfromScience
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A @ScienceTM analysis of trial data from stem cell transplant recipients shows how immune suppression with either cyclophosphamide or tacrolimus shapes T cell reconstitution—and has opposing effects on the risk of graft-versus-host disease or infection post-transplant. scim.ag/47xj5BT
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New in @SciRobotics: The Ultra Mobility Vehicle bicycle robot leverages its own inertia and momentum to perform jumps, track stands, wheelies and other athletic moves. scim.ag/4yyunAT
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How should an underwater exoskeleton be designed to help divers move more efficiently, and are there lessons we can apply from exoskeleton-assisted walking and running? Learn more in this @SciRobotics Focus article: scim.ag/4BcQEa9
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"AI safety needs to be addressed at the level of the human–AI system, not the AI model alone," writes Pietro Michelucci in a new #ScienceEditorial. scim.ag/4zSzwEV
A quote in bold text reads: "... a kill switch cannot by itself serve as a viable or sustainable safety feature." Attributed to Pietro Michelucci from the Human Computation Institute.

ALT A quote in bold text reads: "... a kill switch cannot by itself serve as a viable or sustainable safety feature." Attributed to Pietro Michelucci from the Human Computation Institute.

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A unique human challenge study illuminates how dengue immunity shapes the nature of repeated infections, researchers identify a targetable molecular driver of skin inflammation in psoriasis, and more this week in #ScienceTranslationalMedicine. scim.ag/4zgXqds
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Science Advances@ScienceAdvancesOct 28
New research reveals how structural remodeling can alter the spatio-temporal organization of neurotransmission. Learn more in this week’s issue of Science Advances: scim.ag/4e5NHyd
Presynaptic filopodia, protrusions sprouting from nerve cell endings, promote membrane flow to help brain cells release neurotransmitters more closely timed to incoming electrical signals. Synaptic plasticity allows neural circuits to compute and adapt, but just how the structural remodeling of neurons affects their overall communication remains unclear. Jain et al. investigate how these tiny extensions influence the transmission of signals between nerve cells. They found that these extensions create temporary contact with nearby cells and cause the cell membrane to move, resulting in more precisely timed neurotransmitter release. These results reveal how structural remodeling can alter the spatio-temporal organization of neurotransmission. Credit: Jon Moss (Roslin Institute 3D Electron Microscopy Facility, University of Edinburgh) and Daniela Ivanova (University of Edinburgh)

ALT Presynaptic filopodia, protrusions sprouting from nerve cell endings, promote membrane flow to help brain cells release neurotransmitters more closely timed to incoming electrical signals. Synaptic plasticity allows neural circuits to compute and adapt, but just how the structural remodeling of neurons affects their overall communication remains unclear. Jain et al. investigate how these tiny extensions influence the transmission of signals between nerve cells. They found that these extensions create temporary contact with nearby cells and cause the cell membrane to move, resulting in more precisely timed neurotransmitter release. These results reveal how structural remodeling can alter the spatio-temporal organization of neurotransmission. Credit: Jon Moss (Roslin Institute 3D Electron Microscopy Facility, University of Edinburgh) and Daniela Ivanova (University of Edinburgh)

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A new @ScienceAdvances study proposes the Bacillus Calmette-Guérin vaccine as a preventative measure against dementia. The vaccine reduces Alzheimer’s-associated phospho-tau proteins, reprograms myeloid immune cells and limits neuroinflammation. scim.ag/47Dk9nR
A comparative illustration of neuroinflammation in PS19 FTLD-tauopathy versus BCG-treated PS19 conditions. On the left, PS19 FTLD-tauopathy features reactive astrocytes, activated microglia, and proinflammatory cytokines, leading to neuronal degeneration, tau protein tangles, and cognitive decline as shown by a distressed mouse icon. On the right, BCG-treated PS19 shows resting microglia, healthy neurons, and a stabilized environment with reduced neuroinflammation and improved cognitive function, represented by a healthier mouse icon.

ALT A comparative illustration of neuroinflammation in PS19 FTLD-tauopathy versus BCG-treated PS19 conditions. On the left, PS19 FTLD-tauopathy features reactive astrocytes, activated microglia, and proinflammatory cytokines, leading to neuronal degeneration, tau protein tangles, and cognitive decline as shown by a distressed mouse icon. On the right, BCG-treated PS19 shows resting microglia, healthy neurons, and a stabilized environment with reduced neuroinflammation and improved cognitive function, represented by a healthier mouse icon.

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Carrion crows make decisions faster than monkeys and humans. Learn more in a new #SciencePerspective: scim.ag/4zmOF1i
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By studying sea slugs in the lab, researchers have determined how structural changes in molecules called transfer RNAs accompany behavioral habituation, an elemental form of learning. @SciSignal scim.ag/3UiULAO
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Poetry and other art forms can play a vital role in conservation by giving emotional and cultural meaning to scientific evidence, argue Phillip Levin and David Hassler in a new #ScienceBooks essay. Learn more: scim.ag/4yMAwtk
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