Cell Biology meets Immunology and Virology, spiced up with nanobodies
Bonn, Germany
Joined May 2018
- Tweets549
- Following462
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FISchmidtLab retweeted
How could we identify key genes involved in any biological process and cell type? Please read on about Nuclear In-Situ Sequencing (NIS-Seq)
nature.com/articles/s41587-0…
FISchmidtLab retweeted
and so it begins.....science needs to start getting serious about how how to deal with this type of attacks, sowing distrust.
FISchmidtLab retweeted
It is out! #NanoPlex is the universal strategy for multiplexing any immunofluorescence using erasable #nanobodies from @_NanoTag_. We showcase easy multiplexed STED, STORM, and 21-plex Confocal #Microscopy. Published in @NatureComms here: rdcu.be/dWvzO
FISchmidtLab retweeted
😯😯
It is out! #NanoPlex is the universal strategy for multiplexing any immunofluorescence using erasable #nanobodies from @_NanoTag_. We showcase easy multiplexed STED, STORM, and 21-plex Confocal #Microscopy. Published in @NatureComms here: rdcu.be/dWvzO
FISchmidtLab retweeted
Teaching the next generation of scientists all about what we do in the lab #TürenaufmitderMaus – big thank you to my whole lab and, in particular, Fabian @IIIBonn @for5547 #sfb1454 @ImmunoSens
FISchmidtLab retweeted
Epic effort from Flo & first author Lisa Schiffelers of @FISchmidtLab .
Antagonistic camelid #nanobodies are small enough to traverse early #GSDMD pores to inhibit further #pore #formation.
Monomers target the membrane, suggesting #monomer to #oligomer transition on #membrane.
Ever wondered why there is so little #microscopy of #GSDMD pores? Check out how Lisa Schiffelers used #Nanobodies to stabilize monomeric GSDMD in the plasma membrane, to dissect the steps of pore formation, and to develop some new ideas for therapy.
nature.com/articles/s41467-0…
FISchmidtLab retweeted
✨Today officially marks 10 years of @TheDohertyInst. From pioneering research on the immune system to our response to COVID-19, we’re incredibly proud of our staff and students and their achievements in infection and immunity. And a huge thank you to our supporters. Here’s to another 10 years and beyond! go.unimelb.edu.au/2cc8 @UniMelbMDHS @TheRMH @UniMelb
FISchmidtLab retweeted
Honored to win the Alessandro Moretta Memorial Award.
Fantastic science in a wonderful setting in Greece.
@ragoninstitute @harvardmed @AegeanConf
Congratulations to colleague and friend Charles Evavold (pictured on the right) on winning the Alessandro Moretta award at the 19th Innate Immunity @AegeanConf!
FISchmidtLab retweeted
The #Evavold lab @ragoninstitute is hiring a new #technician.
Please retweet & share the link below.
Ideal for recent grads looking for a couple years of research experience prior to MD or PhD.
partners.taleo.net/careersec…
FISchmidtLab retweeted
Thrilled that our huge team effort with @Kornfeld_JanW is out in @NatMetabolism 🥳 supported by @TRR_BATenergy A huge thank you to all collaborators! If you want to know how a truncated AC3 isoform regulates #BAT function, have a look here nature.com/articles/s42255-0…
FISchmidtLab retweeted
.@Miriam_Pinilla_ @INFLAME_IPBS et al. address the ability of human NLRP1 #inflammasome-forming sensor to detect translation inactivation by bacterial toxins. hubs.la/Q02t0QSG0
In our collection on Innate Immune Signaling: hubs.la/Q02t0SLh0
#TOLL2024
FISchmidtLab retweeted
Check out the preprint of our new method to determine individual proteinuria of all glomeruli in a whole murine kidney, which is based on a navigation software-like approach kidney-international.org/art… @IMMEI_Bonn @UniklinikBonn @UniBonn @HCM_Bonn
FISchmidtLab retweeted
We are looking for a postdoc to join our team @WWIEM_QUB - this is a 3 year MRC funded position to investigate ferritin and inflammasome activation in ARDS in collaboration with @ceciliaokane and @dfmcauley Please apply at shorturl.at/jvPRW DM me for more info! Please RT!
FISchmidtLab retweeted
Rapid protection against viral infections by chemokine-accelerated post-exposure vaccination frontiersin.org/articles/10.…
Happy to share our latest publication showing how chemokines accelerate vaccination success.
FISchmidtLab retweeted
Prof. Radosław P. Nowak hat die neue #Professur für „Immune Engineering and Drug Discovery“ am Institut für #Strukturbiologie des Universitätsklinikums #Bonn (UKB) angetreten. #ukbonn
ukbnewsroom.de/experte-fuer-…
FISchmidtLab retweeted
Our sybody selection toolbox has reached a milestone with 100+ requests on @Addgene! We're thrilled to receive a Blue Flame Award!🔥
Get to know some published sybodies: nitter.cf/seegerlab/status/16377…
Discover #sybodies 🔬: Powerful synthetic nanobodies for tough targets like membrane proteins & complexes! Open access selection protocol at @naturemethods & free library shipping for research groups🌍. nature.com/articles/s41596-0…
FISchmidtLab retweeted
Ever wonder how an uninfected cell is protected from damage during infection and inflammation? 🚫☠️ And how does the infected cell catch its intruder? 👽 Tune in next Monday 20th Nov 4pm GMT, 11am EST, 8am PT for my talk 👇
InflammaZoomers! Don't miss our effector triggered immunity seminar on 20th November featuring @FrickelLab and @psmitchej and hosted by @COdendall NB you will need to re-register as we have moved to a new hosting platform!!!
events.abcam.com/event/d09ed… #InflammaZoom @InflammaZoom
FISchmidtLab retweeted
Very excited to see this out in press. An effort led by @saimamaysidik and Dylan Valleau to understand the function of the CLAMP complex in apicomplexan parasites!
A conserved complex of microneme proteins mediates rhoptry discharge in #Toxoplasma:
@LouridoLab @WhiteheadInst @MITBiology show that three #apicomplexan-specific #microneme proteins form a complex essential for #rhoptry discharge and invasion
embopress.org/doi/full/10.15…
FISchmidtLab retweeted
I am super happy for having the opportunity to present our recent work on vascularized lung organoids at the 2nd Niche-epithelial Stem Cell Interactions in Lung Health and Disease Conference in Dubrovnik #FusionLung2023
