Drug2Cell
github.com/Teichlab/drug2cel…
Drug target discovery using single-cell/-nucleus transcriptomics data
Parse ChEMBL database (>24 M bioactivity records) into drugs & their targets
Per-cell scoring + Marker enrichment
@kazukane @teichlab @Nature 2023
nature.com/articles/s41586-0…
Approaches to Organelle Spacing at Membrane Contact Sites - PubMed share.google/TvFDUj0tbmUKiOS…
Thanks to the editorial board and reviewers for their feedback, which helped to shape this text!
GiacomelloLab retweeted
Thanks to James, Alyssa and the whole team for getting this story out in Nature.
1/ Thrilled to share our new paper in @Nature: “CLCC1 promotes hepatic neutral lipid flux and nuclear pore complex assembly.” From our lab together with @apsarruda, led by co–first authors @alymathiowetz and @EmilyMeymand. 🥳
nature.com/articles/s41586-0…
GiacomelloLab retweeted
Throwback to our 1st Membrane Contact Sites Meeting back in 2024!
Luca, Thomas & Rosie look forward to reuniting in Mexico later this year, and welcoming our new, and returning delegates from the MCS community
Our final programme is now live, so visit the website here to check out what we have instore over the 4 day programme: bit.ly/4yynf8X
#MembraneContactSites
GiacomelloLab retweeted
The 2025 @EMBO Contact Sites meeting was extraordinary. Congratulations to @CampanellaMiche and @PaillardMel .
meetings.embo.org/event/25-m…
Marta @GiacomelloLab and I are already working to make the 2027 meeting memorable.
Keep in touch (like a contact site). It will be 🔥 🔥 🔥
GiacomelloLab retweeted
Want to predict post-translational modifications Phosphorylation/Acetylation/Ubiquitination/Acylation/Methylation... of proteins of interest?👇
PhosphoSitePlus
phosphosite.org/homeAction
@NAR_Open 2014
academic.oup.com/nar/article…
Even powered up by recent human Kinomes
An atlas of substrate specificities for the human serine/threonine kinome
@Nature 2023
nature.com/articles/s41586-0…
The intrinsic substrate specificity of the human tyrosine kinome
@Nature 2024
nature.com/articles/s41586-0…
GiacomelloLab retweeted
Il Career Service dell'Università di Padova organizza anche per l'a.a. 2024/25 i laboratori esperienziali per lo sviluppo di competenze trasversali, rivolti a studenti, studentesse e neolaureati/e.
Inizio: 6 marzo 2025. Scadenza: 7 febbraio 2025.
Info: unipd.it/laboratori-sviluppo…
GiacomelloLab retweeted
EMBO meeting on membrane contact sites - 28 September - 03 October 2025
Outstanding science, amazing scenery.
Open for business!
meetings.embo.org/event/25-m…
GiacomelloLab retweeted
Very proud to sign a letter by which IOCB Prague (together with Rega Institute Leuven and Gilead Science in Foster City) surrenders its licensing fees for the HIV drugs invented in Prague/Leuven for 136 low and middle-income countries. Merry Christmas to all.
GiacomelloLab retweeted
Thank you @TheVFoundation for this invaluable support as we establish our research program! 🙏🧬
This is who you’re supporting. 100% of the money you give is going directly to researchers like our grantee, Dr. Christina @glytsou.
Mitochondria - melanosomes contact sites: in a timely manner?!
@LEOFondet
nitter.cf/GiacomelloLab/status/1…
GiacomelloLab retweeted
🚨Exciting Opportunity!🚨
The University of Udine is recruiting researchers for a project on Spinal Muscular Atrophy (SMA), focusing on pioneering microRNA (miRNA) therapies.
📩 Reach out to Dr. Camilla Bean for details: [email protected]
Please repost!
GiacomelloLab retweeted
Amazing in situ cryo-EM imaging techniques for direct visualization of supercomplexes structures within mitochondria, preserving both the native membrane environment and the electrochemical proton gradient!
nature.com/articles/s41586-0…




















